Academic Journals Database
Disseminating quality controlled scientific knowledge

Search Articles for "Drug discovery"

ADD TO MY LIST
 
Modeling Natural Anti-Inflammatory Compounds by Molecular Topology

Author(s): María Galvez-Llompart | Riccardo Zanni | Ramón García-Domenech
Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of ADAMTS1 Inhibitors

Author(s): Jianhao Peng | Lili Gong | Kun Si | Xiaoyu Bai | Guanhua Du
IN SILICO MODELLING AND DRUG DESIGN – A REVIEW

Author(s): Gupta Praveen kumar | Agrawal Pushpa | Shivakumar Neeta | Hiremath Suhasini.B
Is combinatorial chemistry on the right track for drug discovery?

Author(s): Richard A. Wildonger | Tracy L. Deegan | John W. Lee
Beyond Range: Innovating Fluorescence Microscopy

Author(s): Alessandro Esposito
QUINAZOLINONE: AN OVERVIEW

Author(s): Arora Rashmi | Kapoor Ashish | Gill N.S | Rana A.C
Serendipity in anticancer drug discovery

Author(s): Emily Hargrave-Thomas | Bo Yu | Jóhannes Reynisson
MiRNAs and LincRNAs: Could They Be Considered as Biomarkers in Colorectal Cancer?

Author(s): Ruth Zarate | Valentina Boni | Eva Bandres | Jesús Garcia-Foncillas
Harungana madagascariensis in acute and repeated acetaminophen hepatotoxic rats

Author(s): A A Adeneye | J A Olagunju | S O Elias | D O Olatunbosun | A O Mustafa | O I Adeshile | A O Ashaolu | T A Laoye | A O Bamigboye | A O Adeoye
PLANT PRODUCTS POTENTIAL AS ANTI-ANGIOGENIC AND IN CANCER MANAGEMENT

Author(s): Patil Kalpana S. | Bhardwaj Lokesh K | Juvatkar P.V. | Shukla V.K. | Manvi F.V.
MICRONEEDLE: AS A FUTURE PROSPECTIVE TOOL

Author(s): Arora Neha | Singh Kamaljit | Bilandi Ajay | Garg Tarun
Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation

Author(s): Lee P | Zhang R | Li V | Liu X | Sun RWY | Che CM | Wong KKY
Analog based pharmacophore strategy to identify novel leukotriene a4 hydrolase (LTA4H) inhibitors

Author(s): Kranthi Raj K, Pathak LP, Muttineni Ravikumar, Ramachandrana D
THE CHALLENGES OF OPHTHALMIC DRUG DELIVERY: A REVIEW

Author(s): SINGH V, AHMAD R, HEMING T
A LINEAR QSAR AND DOCKING APPROACH TO MODEL INHIBITORY ACTIVITY OF 2-ARYLBENZOXAZOLE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITORS

Author(s): MUKESH YADAV, ANURAJ NAYARISSERI, SHOBHA JOSHI, ANKITA GUPTA, PURVA HOLKAR, ASHISH RAJPUT, RISHABH JAIN
AN INVESTIGATION ON CYTOTOXIC AND ANTIOXIDANT PROPERTIES OF CLITORIA TERNATEA L

Author(s): VIDHYA RAMASWAMY, NEETHU VARGHESE, ANCY SIMON
Regulation of colon cancer recurrence and development of therapeutic strategies

Author(s): Shailender Singh Kanwar | Anuradha Poolla | Adhip PN Majumdar
Novel Technology for Protein-Protein Interaction-based Targeted Drug Discovery

Author(s): Jung Me Hwang | Kyung-Bok Lee | Jong-Soon Choi | Jaerang Rho | Gun-Hwa Kim | Seung Il Kim | Soohyun Kim | Zee-Won Lee
Changes in A2A adenosine receptor parameters in patients affected by bipolar disorders: Correlation with antipsychotic dosage and severity of illness

Author(s): Donatella Marazziti | Gabriele Massimetti | Claudia Martini | Liliana Dell’Osso | Simona Daniele | Maria Letizia Trincavelli | Mario Catena Dell’Osso | Antonio Ciapparelli
Dynamic Structure-Based Pharmacophore Model Development: A New and Effective Addition in the Histone Deacetylase 8 (HDAC8) Inhibitor Discovery

Author(s): Sundarapandian Thangapandian | Shalini John | Yuno Lee | Songmi Kim | Keun Woo Lee
Transdermal Drug Delivery Enhancement by Compounds of Natural Origin

Author(s): Lizelle T. Fox | Minja Gerber | Jeanetta Du Plessis | Josias H. Hamman
Phase 0 clinical trial- an overview

Author(s): Aanchal Satija
Drug-resistant tuberculosis: emerging treatment options

Author(s): Adhvaryu MR | Vakharia BC
The Story of Azithromycin

Author(s): Banić Tomišić, Z.
Ionic Channels as Targets for Drug Design: A Review on Computational Methods

Author(s): Gregorio Fernández-Ballester | Asia Fernández-Carvajal | José Manuel González-Ros | Antonio Ferrer-Montiel
Discovery of Potential M2 Channel Inhibitors Based on the Amantadine Scaffold via Virtual Screening and Pharmacophore Modeling

Author(s): Linh Tran | Sy Bing Choi | Belal O. Al-Najjar | Muhammad Yusuf | Habibah A. Wahab | Ly Le
Treatment of Huntington's disease Using Medieval Iranian Practice

Author(s): Mohammad Reza Sailani | Zohreh Hojati | Maryam Amiri | Liana Lachinani
Advancement into the Arctic Region for Bioactive Sponge Secondary Metabolites

Author(s): Samuel Abbas | Michelle Kelly | John Bowling | James Sims | Amanda Waters | Mark Hamann
Spleen transcriptome response to infection with avian pathogenic Escherichia coli in broiler chickens

Author(s): Sandford Erin | Orr Megan | Balfanz Emma | Bowerman Nate | Li Xianyao | Zhou Huaijun | Johnson Timothy | Kariyawasam Subhashinie | Liu Peng | Nolan Lisa | Lamont Susan
In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling

Author(s): Becker John | van der Merwe Marina | van Brummelen Anna | Pillay Pamisha | Crampton Bridget | Mmutlane Edwin | Parkinson Chris | van Heerden Fanie | Crouch Neil | Smith Peter | Mancama Dalu | Maharaj Vinesh
Non-invasive muscle contraction assay to study rodent models of sarcopenia

Author(s): Chiu Chi-Sung | Weber Hans | Adamski Sharon | Rauch Albert | Gentile Michael | Alves Stephen | Kath Gary | Flores Osvaldo | Wilkinson Hilary
Rigid Molecule Docking: FPGA Reconfiguration for Alternative Force Laws

Author(s): VanCourt Tom | Gu Yongfeng | Mundada Vikas | Herbordt Martin
New directions in migraine

Author(s): Weir Greg | Cader M Zameel
In Silico Identification of Structure Requirement for Novel Thiazole and Oxazole Derivatives as Potent Fructose 1,6-Bisphosphatase Inhibitors

Author(s): Ming Hao | Xiaole Zhang | Hong Ren | Yan Li | Shuwei Zhang | Fang Luo | Mingjuan Ji | Guohui Li | Ling Yang
DOCKING STUDIES ON NOVEL HUMAN CARBONIC ANHYDRASE II

Author(s): M. Vinoth | G. Jhansi Rani | P. Anitha
Applications of Next-Generation Sequencing Technologies to Diagnostic Virology

Author(s): Luisa Barzon | Enrico Lavezzo | Valentina Militello | Stefano Toppo | Giorgio Palù
MAOS and Medicinal Chemistry: Some Important Examples from the Last Years

Author(s): Nailton M. Nascimento-Júnior | Arthur E. Kümmerle | Eliezer J. Barreiro | Carlos A. M. Fraga
In silico prioritization of some quinazolinone for anticonvulsant activity

Author(s): K. S. Lade*, A. G. Nerkar, and S.D.Sawant
Pharmacotherapy of schizophrenia

Author(s): Shahin Akhondzadeh | Khosro Afkham
In-silico docking studies on anticancerous polyphenolic phytocompounds targeting the BH3 domain of Bcl-xL receptor in apoptotic pathway

Author(s): Daisy Pitchai*, Rajalakshmi Manikkam, Suveena Sukumaran,SaiPriya Kandhasamy, Vijayalakshmi Periyasamy
Synthesis of some new 1,3,4-thiadiazoles as antimicrobial agents

Author(s): N. Venu Madhav1*, A. Srinivas Nayak4, J. Venkateswar Rao3 and M. Sarangapani2
Stem Cells in Drug Discovery: Current trends and Emerging Challenges

Author(s): Senthil Kumar Pazhanisamy | Vinu Jyothi
Corrigendum

Author(s): Skibinski G | Finkbeiner S
Marine algae: An Introduction, Food value and Medicinal uses

Author(s): Ajit Kandale1, A K Meena1*, M M Rao1, P Panda1, AK Mangal1 G Reddy3 and Ramesh Babu2
Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering

Author(s): Karim Senni | Jessica Pereira | Farida Gueniche | Christine Delbarre-Ladrat | Corinne Sinquin | Jacqueline Ratiskol | Gaston Godeau | Anne-Marie Fischer | Dominique Helley | Sylvia Colliec-Jouault
High-Density Real-Time PCR-Based in Vivo Toxicogenomic Screen to Predict Organ-Specific Toxicity

Author(s): Gabriella Fabian | Nora Farago | Liliana Z. Feher | Lajos I. Nagy | Sandor Kulin | Klara Kitajka | Tamas Bito | Vilmos Tubak | Robert L. Katona | Laszlo Tiszlavicz | Laszlo G. Puskas
DDTRP: Database of Drug Targets for Resistant Pathogens

Author(s): Jagadish Chandrabose Sundaramurthi | Prabhakaran Ramanandan | Sridharan Brindha | Chelladurai Ramarathnam Subhasree | Abhimanyu Prasad | Vasanthapuram Kumaraswamy | Luke Elizabeth Hanna*
New inhibitors of VEGFR-2 targeting the extracellular domain dimerization process

Author(s): Mohammad Amine ElGamacy | Raed Ahmed Shalaby | Ahmad Tawfik Elkodsh | Amr Fawzy Kamel | Mohamed Saad Abdullah Elsayed* | Dalal Abd El Rahman Abou-El-Ella
Lobohedleolide induces interleukin-8 production in LPS-stimulated human monocytic cell line THP-1

Author(s): T Oda | WS Wewengkang | M M Kapojos | RE P Mangindaan | J-S Lee | M Namikoshi
Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine

Author(s): Holbrook Joanna | Parker Joel | Gallagher Kathleen | Halsey Wendy | Hughes Ashley | Weigman Victor | Lebowitz Peter | Kumar Rakesh
The Budding Yeast “Saccharomyces cerevisiae” as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties

Author(s): Bouchra Qaddouri | Abdelkarim Guaadaoui | Ahmed Bellirou | Abdellah Hamal | Ahmed Melhaoui | Grant W. Brown | Mohammed Bellaoui
Structural Library of Natural Compounds

Author(s): Subhash Chandra Bose Kotte | K V T S Pavan Kumar | T Ravi Kumar | Shriram Raghavan | P K Dubey | P M Murali
Les projectiles toxiques antipersonnel modernes

Author(s): Gaillard Yvan | Regenstreif Philippe | Fanton Laurent
COMBINATORIAL CHEMISTRY: AN OVERVIEW

Author(s): V.S. Tegeli*, G.B. Gajeli, G.K. Chougule, Y.S. Thorat, U.S. Shivsharan, S.T. Kumbhar,
Electronic Nose: A New Artificial Olfactory Sensor

Author(s): Hitesh Jain*1, Shweta Gediya1, Monica Padaria1, T. Y. Pasha2
DIVERSITY, DISTRIBUTION AND BIOLOGICAL ACTIVITY OF SOFT CORALS (OCTOCORALLIA, ALCYONACEA) IN SINGAPORE

Author(s): Beverly Pi Lee Goh*, Grace Enhui Tan, and Lik Tong Tan*
Crystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroate

Author(s): Morgan Rachel | Batot Gaëlle | Dement Jennifer | Rao Vincenzo | Eadsforth Thomas | Hunter William
Stem cell biology and drug discovery

Author(s): Rubin Lee | Haston Kelly
Development of a novel DDS for site-specific PEGylated proteins

Author(s): Yoshioka Yasuo | Tsunoda Shin-ichi | Tsutsumi Yasuo
A review of health system infection control measures in developing countries: what can be learned to reduce maternal mortality

Author(s): Hussein Julia | Mavalankar Dileep | Sharma Sheetal | D'Ambruoso Lucia
Exploring NMR ensembles of calcium binding proteins: Perspectives to design inhibitors of protein-protein interactions

Author(s): Isvoran Adriana | Badel Anne | Craescu Constantin | Miron Simona | Miteva Maria
Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades

Author(s): Andersen Finn | Douglas Nick | Bustos Dorina | Galappaththy Gawrie | Qi Gao | Hsiang Michelle | Kusriastuti Rita | Mendis Kamini | Taleo George | Whittaker Maxine | Price Ric | von Seidlein Lorenz
Two-stage flux balance analysis of metabolic networks for drug target identification

Author(s): Li Zhenping | Wang Rui-Sheng | Zhang Xiang-Sun
Discrimination of approved drugs from experimental drugs by learning methods

Author(s): Tang Kailin | Zhu Ruixin | Li Yixue | Cao Zhiwei
Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope

Author(s): Hesketh Andy | Hill Chris | Mokhtar Jehan | Novotna Gabriela | Tran Ngat | Bibb Mervyn | Hong Hee-Jeon
Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus

Author(s): Overton Ian | Graham Shirley | Gould Katherine | Hinds Jason | Botting Catherine | Shirran Sally | Barton Geoffrey | Coote Peter
Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction

Author(s): Fang Kechi | Zhao Hansheng | Sun Changyue | Lam Carolyn | Chang Suhua | Zhang Kunlin | Panda Gurudutta | Godinho Miguel | Martins dos Santos Vítor | Wang Jing
Predicting drug side-effect profiles: a chemical fragment-based approach

Author(s): Pauwels Edouard | Stoven Véronique | Yamanishi Yoshihiro
Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer

Author(s): Toyokawa Gouji | Masuda Ken | Daigo Yataro | Cho Hyun-Soo | Yoshimatsu Masanori | Takawa Masashi | Hayami Shinya | Maejima Kazuhiro | Chino Makoto | Field Helen | Neal David | Tsuchiya Eiju | Ponder Bruce | Maehara Yoshihiko | Nakamura Yusuke | Hamamoto Ryuji
Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing

Author(s): Durban Jordi | Juárez Paula | Angulo Yamileth | Lomonte Bruno | Flores-Diaz Marietta | Alape-Girón Alberto | Sasa Mahmood | Sanz Libia | Gutiérrez José | Dopazo Joaquín | Conesa Ana | Calvete Juan
Untapped ethical resources for neurodegeneration research

Author(s): Robillard Julie | Federico Carole | Tairyan Kate | Ivinson Adrian | Illes Judy
Semantic inference using chemogenomics data for drug discovery

Author(s): Zhu Qian | Sun Yuyin | Challa Sashikiran | Ding Ying | Lajiness Michael | Wild David
Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)

Author(s): Bachstetter Adam | Xing Bin | de Almeida Lucia | Dimayuga Edgardo | Watterson D Martin | Van Eldik Linda
The BioAssay network and its implications to future therapeutic discovery

Author(s): Zhang Jintao | Lushington Gerald | Huan Jun
Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment

Author(s): Wahlstrom Jan | Chiang Po-Chang | Ghosh Sarbani | Warren Chad | Wene Steve | Albin Lesley | Smith Mark | Roberds Steven
Review and application of group theory to molecular systems biology

Author(s): Rietman Edward | Karp Robert | Tuszynski Jack
MTB-PCDB: Mycobacterium tuberculosis proteome comparison database

Author(s): Lingaraja Jena | Satish Kumar | Bhaskar Chinnaiah Harinath | Gauri Wankhade
Variability analyses of functional domains within glucosamine-6-phosphate synthase of mycosescausing fungi

Author(s): Utkarsh Gupta | Reema Gabrani | Sanjay Gupta | Sanjeev Kumar Sharma | Chakresh Kumar Jain | Kamalika Banerjee
Docking study of HIV-1 reverse transcriptase with phytochemicals

Author(s): Abhik Seal | Riju Aykkal | Mriganka Ghosh
Database on pharmacophore analysis of active principles, from medicinal plants

Author(s): Daisy Pitchai | Rajalakshmi Manikkam | Gnanamani Pitchai | Sasikala R. Rajendran
Health and Gross National Happiness: review of current status in Bhutan

Author(s): Tobgay T | Dophu U | Torres CE | Na-Bangchang K
A model for the evaluation of domain based classification of GPCR

Author(s): Tannu Kumari | Bhaskar Pant | Kamalraj R. Pardasani
Insight to pyrazinamide resistance in Mycobacterium tuberculosis by molecular docking

Author(s): A. Nusrath Unissa | N. Selvakumar | Sameer Hassan
Identification of potential apicoplast associated therapeutic targets in human and animal pathogen Toxoplasma gondii ME49

Author(s): Sadegh Saremy | Biplab Bhattacharjee* | Mahdi Eskandarian Boroujeni | Jhinuk Chatterjee | Viditi Mittal
Hidden markov model for the prediction of transmembrane proteins using MATLAB

Author(s): Navaneet Chaturvedi* | Vinay Kumar Singh3 | Sudhanshu Shanker2 | Dhiraj Sinha4 | Paras Nath Pandey5
Save time & money - Smart Internet Solutions      Why do you need a reservation system?