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Synthesis and Antimalarial Activity of Novel Dihydro-Artemisinin Derivatives

Author(s): Yang Liu | Kunqiang Cui | Weiqiang Lu | Wei Luo | Jian Wang | Jin Huang | Chun Guo
IN SILICO MODELLING AND DRUG DESIGN – A REVIEW

Author(s): Gupta Praveen kumar | Agrawal Pushpa | Shivakumar Neeta | Hiremath Suhasini.B
A Review of Antisense Therapeutic Interventions for Molecular Biological Targets in Various Diseases

Author(s): Jasbir Singh | Harmeet Kaur | Aditi Kaushik | Sapna Peer
Novel ocular antihypertensive compounds in clinical trials

Author(s): Chen J | Runyan SA | Robinson MR
Cytochrome P450 mRNA expressions along with in vitro differentiation of hepatocyte precursor cells from fetal, young and old rats.

Author(s): Piotr Czekaj | Aleksandra Bryzek | Tomasz M Czekaj | Halina Koryciak-Komarska | Anna Wiaderkiewicz | Danuta Plewka | Aleksander L Sieroń
DAPAGLIFLOZIN: SELECTIVE SODIUM-GLUCOSE CO-TRANSPORTER-2 INHIBITOR IN TYPE 2 DIABETES

Author(s): Sudhakar Pemminati | Ashok K Shenoy | Yugandhar B | Ullal SD | Ratnakar UP | Gopalakrishna HN | Preethi G Pai | Rajeshwari S
Early Biventricular Molecular Responses to an Acute Myocardial Infarction

Author(s): Cenk Erdal, Gökhan Karakülah, Emel Fermancı, İmge Kunter, Erdem Silistreli, Tülay Canda, Esra Erdal, Hasan Hepaguslar
The Complementarity Effect for Cdc25 Phosphatase Inhibitors

Author(s): Wassila Soufi | Meriem Merad | Faïza Boukli | Saïd Ghalem
Adaptation of High-Throughput Screening in Drug Discovery—Toxicological Screening Tests

Author(s): Paweł Szymański | Magdalena Markowicz | Elżbieta Mikiciuk-Olasik
MiRNAs and LincRNAs: Could They Be Considered as Biomarkers in Colorectal Cancer?

Author(s): Ruth Zarate | Valentina Boni | Eva Bandres | Jesús Garcia-Foncillas
HIV/AIDS Situation in Economic Cooperation Countries; Achievement and Gaps toward Millennium Development Goals

Author(s): Ghobad Moradi | Hossein Malekafzali | Kourosh Holakouie Naieni | Arash Rashidian | Parviz Vazirian | Ali Mirzazadeh | Hojjat Allah Barati
NEW DRUG REGIMENS FOR OLD DISEASE TUBERCULOSIS: A REVIEW

Author(s): Gupta Sandeep | Sharma Mona | Gupta Mahesh Kumar | Nagla Kapil | Gupta Raman
Metabolic pathway analysis and molecular docking analysis for identification of putative drug targets in Toxoplasma gondii: novel approach

Author(s): Budhayash Gautam1 | Gurmit Singh | Gulshan Wadhwa | Rohit Farmer | Satendra Singh | Atul Kumar Singh | Prashant Ankur Jain | Pramod Kumar Yadav
Insight into trichomonas vaginalis genome evolution through metabolic pathways comparison

Author(s): Satendra Singh | Gurmit Singh | Nitin Sagar | Pramod Kumar Yadav | Prashant A Jain | Budhayash Gautam | Gulshan Wadhwa
Indolin-2-Ones in Clinical Trials as Potential Kinase Inhibitors: A Review

Author(s): Sundararajan Raja | Panneerselvam Theivendren | Chinnasamy Rajaram Prakash
α-Mangostin Enhances Betulinic Acid Cytotoxicity and Inhibits Cisplatin Cytotoxicity on HCT 116 Colorectal Carcinoma Cells

Author(s): Abdalrahim F. A. Aisha | Khalid M. Abu-Salah | Zhari Ismail | Amin Malik Shah Abdul Majid
Drug-resistant tuberculosis: emerging treatment options

Author(s): Adhvaryu MR | Vakharia BC
PUTATIVE DRUG TARGET IDENTIFICATION FOR CHLAMYDIA TRACHOMATIS: AN INSILICO PROTEOME ANALYSIS

Author(s): Praveena A. | R. Sindhuja | Anuradha V. | S.K.M. Habeeb
Ionic Channels as Targets for Drug Design: A Review on Computational Methods

Author(s): Gregorio Fernández-Ballester | Asia Fernández-Carvajal | José Manuel González-Ros | Antonio Ferrer-Montiel
Protein Databases

Author(s): Zarrin Minuchehr | Bahram Goliaei
Study of Celastrol on Akt Signaling Pathway and Its Roles in the Apoptosis of K562 Cells

Author(s): Xiaonan Wang | Qing Wu | Xu Yang | Liansheng Zhang | Yiping Wu | Yanwen Shu
Mitocans as Novel Agents for Anticancer Therapy: An Overview

Author(s): Vandana Panda | Prashant Khambat | Sachin Patil
Molecular docking of glucosamine-6-phosphate synthase in Rhizopus oryzae

Author(s): Kamalika Banerjee | Utkarsh Gupta | Sanjay Gupta | Gulshan Wadhwa | Reema Gabrani | Sanjeev Kumar Sharma | Chakresh Kumar Jain
Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer

Author(s): Elfiky Aymen | Aziz Saadia | Conrad Patricia | Siddiqui Summar | Hackl Wolfgang | Maira Michel | Robert Camp | Kluger Harriet
Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

Author(s): Yang Lei | Rau Martin | Yang Liang | Høiby Niels | Molin Søren | Jelsbak Lars
The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases

Author(s): Cadavid-Restrepo Gloria | Gastardelo Thiago | Faudry Eric | de Almeida Hugo | Bastos Izabela | Negreiros Raquel | Lima Meire | Assumpção Teresa | Almeida Keyla | Ragno Michel | Ebel Christine | Ribeiro Bergmann | Felix Carlos | Santana Jaime
Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism

Author(s): Sureban Sripathi | May Randal | Mondalek Fadee | Qu Dongfeng | Ponnurangam Sivapriya | Pantazis Panayotis | Anant Shrikant | Ramanujam Rama | Houchen Courtney
Spleen transcriptome response to infection with avian pathogenic Escherichia coli in broiler chickens

Author(s): Sandford Erin | Orr Megan | Balfanz Emma | Bowerman Nate | Li Xianyao | Zhou Huaijun | Johnson Timothy | Kariyawasam Subhashinie | Liu Peng | Nolan Lisa | Lamont Susan
Transgenic Plasmodium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in vivo models for antifolate screening

Author(s): Somsak Voravuth | Uthaipibull Chairat | Prommana Parichat | Srichairatanakool Somdet | Yuthavong Yongyuth | Kamchonwongpaisan Sumalee
Removing bias against membrane proteins in interaction networks

Author(s): Brito Glauber | Andrews David
VIP and endothelin receptor antagonist: An effective combination against experimental pulmonary arterial hypertension

Author(s): Hamidi Sayyed | Lin Richard | Szema Anthony | Lyubsky Sergey | Jiang Ya | Said Sami
Tumour macrophages as potential targets of bisphosphonates

Author(s): Rogers Thea | Holen Ingunn
Time-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation

Author(s): Wangorsch Gaby | Butt Elke | Mark Regina | Hubertus Katharina | Geiger Jörg | Dandekar Thomas | Dittrich Marcus
New directions in migraine

Author(s): Weir Greg | Cader M Zameel
BACE-1 inhibition prevents the γ-secretase inhibitor evoked Aβ rise in human neuroblastoma SH-SY5Y cells

Author(s): Jämsä Anne | Belda Oscar | Edlund Michael | Lindström Erik
Neoamphimedine Circumvents Metnase-Enhanced DNA Topoisomerase IIα Activity Through ATP-Competitive Inhibition

Author(s): Jessica Ponder | Byong Hoon Yoo | Adedoyin D. Abraham | Qun Li | Amanda K. Ashley | Courtney L. Amerin | Qiong Zhou | Brian G. Reid | Philip Reigan | Robert Hromas | Jac A. Nickoloff | Daniel V. LaBarbera
DRUG DELIVERY BY NANODIAMONDS

Author(s): Prajapati Parimal M1 | Patel Krunal R | Ganatra Maulik H | Solanki Anil S | Sen Dhrubo Jyoti
Computer aided screening and evaluation of herbal therapeutics against MRSA infections

Author(s): Sinosh Skariyachan* | Rao Shruti Krishnan | Snehapriya Bangalore Siddapa | Chithra Salian | Prerana Bhora | Denoj Sebastian
"Flexible Ligand Docking Studies of Matrix Metalloproteinase Inhibitors Using Lamarckian Genetic Algorithm "

Author(s): lOrkideh Ghorban Dadrass | Armin Madadkar Sobhani | Abbas Shafiee | Massoud Mahmoudian
Anti-Inflammatory Drug Design Using a Molecular Hybridization Approach

Author(s): Priscila Longhin Bosquesi | Thais Regina Ferreira Melo | Ednir Oliveira Vizioli | Jean Leandro dos Santos | Man Chin Chung
Use of proteasome inhibitors in anticancer therapy

Author(s): Sara M. Schmitt | Lillian Lu | Q. Ping Dou
Molecular network topology and reliability for multipurpose diagnosis

Author(s): Jalil MA | Moongfangklang N | Innate K | Mitatha S | Ali J, Yupapin PP
Plasmodium falciparum spermidine synthase

Author(s): Anup V. Patwa, Amit G. Nerkar*, Sanjay D. Sawant
The using of «argenate» application in the treatment of caries of deciduous teeth in children at the age from 2 to 6

Author(s): Kolesova O.V. | Kosyuga S.Y. | Balabina T.S. | Volodyashkina M.A. | Veselov D.V.
Nanoemulsions for drug delivery through different routes

Author(s): Ravi Theaj Prakash U. | Padma Thiagarajan
Selection of an improved HDAC8 inhibitor through structure-based drug design

Author(s): Balakrishnan Vijayakumar | Ayarivan Puratchikody | Appavoo Umamaheswari | Devadasan Velmurugan
Target Profile Prediction and Practical Evaluation of a Biginelli-Type Dihydropyrimidine Compound Library

Author(s): Petra Schneider | Katharina Stutz | Ladina Kasper | Sarah Haller | Michael Reutlinger | Felix Reisen | Tim Geppert | Gisbert Schneider
DDTRP: Database of Drug Targets for Resistant Pathogens

Author(s): Jagadish Chandrabose Sundaramurthi | Prabhakaran Ramanandan | Sridharan Brindha | Chelladurai Ramarathnam Subhasree | Abhimanyu Prasad | Vasanthapuram Kumaraswamy | Luke Elizabeth Hanna*
Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine

Author(s): Holbrook Joanna | Parker Joel | Gallagher Kathleen | Halsey Wendy | Hughes Ashley | Weigman Victor | Lebowitz Peter | Kumar Rakesh
The differential disease regulome

Author(s): Sandve Geir | Gundersen Sveinung | Rydbeck Halfdan | Glad Ingrid | Holden Lars | Holden Marit | Liestøl Knut | Clancy Trevor | Drabløs Finn | Ferkingstad Egil | Johansen Morten | Nygaard Vegard | Tøstesen Eivind | Frigessi Arnoldo | Hovig Eivind
A Systems Biology Strategy for Predicting Similarities and Differences of Drug Effects: Evidence for Drug-specific Modulation of Inflammation in Atherosclerosis

Author(s): Kleemann Robert | Bureeva Svetlana | Perlina Ally | Kaput Jim | Verschuren Lars | Wielinga Peter | Hurt-Camejo Eva | Nikolsky Yuri | van Ommen Ben | Kooistra Teake
Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures

Author(s): Spradling Kimberly | Lumley Lucille | Robison Christopher | Meyerhoff James | Dillman James
Involvement of Cox-2 in the metastatic potential of chemotherapy-resistant breast cancer cells

Author(s): Kang Ju-Hee | Song Ki-Hoon | Jeong Kyung-Chae | Kim Sunshin | Choi Changsun | Lee Chang | Oh Seung
The Bone Niche of Chondrosarcoma: A Sanctuary for Drug Resistance, Tumour Growth and also a Source of New Therapeutic Targets

Author(s): E. David | F. Blanchard | M. F. Heymann | G. De Pinieux | F. Gouin | F. Rédini | D. Heymann
A survey on herbal management of hepatocellular carcinoma

Author(s): Nabil Mohie Abdel-Hamid | Maiiada Hasan Nazmy | Ahmed Wahid Mahmoud | Michael Atef Fawzy | Marco Youssof
Functional co-evolutionary study of glucosamine-6-phosphate synthase in mycoses causing fungi

Author(s): Kamalika Banerjee | Sanjay Gupta | Sanjeev Kumar Sharma | Utkarsh Gupta | Chakresh Kumar Jain*
Multi-access drug delivery network and stability

Author(s): Mitatha S | Moongfangklang N | Jalil MA | Suwanpayak N | Ali J | Yupapin PP
ANTIDIABETIC, ANTIHYPERLIPIDEMIC AND ANTIOXIDANT ACTIVITY OF POLYHERBAL FORMULATION

Author(s): Md. Shafiuddin1, Jaspalsinh Parmar1, D.K.Suresh1, Shaikh Azhar Hussain1, Mahesh Shinde1
Unravelling the story of protein misfolding in diabetes mellitus

Author(s): Sally E Thomas | Lucy Dalton | Elke Malzer | Stefan J Marciniak
Aptamer-Gated Nanoparticles for Smart Drug Delivery

Author(s): Veli Cengiz Ozalp | Fusun Eyidogan | Huseyin Avni Oktem
MODELLING OF INFECTIOUS IMMUNOLOGICAL PATHWAY PROTEIN RELATED TO SYSTEMIC LUPUS ERYTHEMATOUS (SLE) ACTING AS DRUG TARGETS

Author(s): G.Shashikanth, James Abraham, Sachidanand Singh*, Atul Kumar, J.Jannet Vennila
Loss of aquaporin-4 expression and putative function in non-small cell lung cancer

Author(s): Warth Arne | Muley Thomas | Meister Michael | Herpel Esther | Pathil Anita | Hoffmann Hans | Schnabel Philipp | Bender Christian | Buness Andreas | Schirmacher Peter | Kuner Ruprecht
Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes

Author(s): Li Yi | Ren Gang | Wang Yan-Xiang | Kong Wei-Jia | Yang Peng | Wang Yue-Ming | Li Ying-Hong | Yi Hong | Li Zhuo-Rong | Song Dan-Qing | Jiang Jian-Dong
IκB kinases increase Myc protein stability and enhance progression of breast cancer cells

Author(s): Yeh Pei-Yen | Lu Yen-Shen | Ou Da-Liang | Cheng Ann-Lii
Do methadone and buprenorphine have the same impact on psychopathological symptoms of heroin addicts?

Author(s): Maremmani Angelo | Rovai Luca | Pani Pier | Pacini Matteo | Lamanna Francesco | Rugani Fabio | Schiavi Elisa | Dell'Osso Liliana | Maremmani Icro
Antiviral activity of Acacia nilotica against Hepatitis C Virus in liver infected cells

Author(s): Rehman Sidra | Ashfaq Usman | Riaz Sana | Javed Tariq | Riazuddin Sheikh
Exploring NMR ensembles of calcium binding proteins: Perspectives to design inhibitors of protein-protein interactions

Author(s): Isvoran Adriana | Badel Anne | Craescu Constantin | Miron Simona | Miteva Maria
Eukaryotic Protein Kinases (ePKs) of the Helminth Parasite Schistosoma mansoni

Author(s): Andrade Luiza | Nahum Laila | Avelar Lívia | Silva Larissa | Zerlotini Adhemar | Ruiz Jerônimo | Oliveira Guilherme
Two-stage flux balance analysis of metabolic networks for drug target identification

Author(s): Li Zhenping | Wang Rui-Sheng | Zhang Xiang-Sun
Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction

Author(s): Fang Kechi | Zhao Hansheng | Sun Changyue | Lam Carolyn | Chang Suhua | Zhang Kunlin | Panda Gurudutta | Godinho Miguel | Martins dos Santos Vítor | Wang Jing
Clinical and Technical Phosphoproteomic Research

Author(s): López Elena | López Isabel | Ferreira Antonio | Sequí Julia
Plasmodial sugar transporters as anti-malarial drug targets and comparisons with other protozoa

Author(s): Slavic Ksenija | Krishna Sanjeev | Derbyshire Elvira | Staines Henry
Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics

Author(s): Feehan Michael | Hartman John | Durante Richard | Morrison Margaux | Miller Joan | Kim Ivana | DeAngelis Margaret
The BioAssay network and its implications to future therapeutic discovery

Author(s): Zhang Jintao | Lushington Gerald | Huan Jun
Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment

Author(s): Wahlstrom Jan | Chiang Po-Chang | Ghosh Sarbani | Warren Chad | Wene Steve | Albin Lesley | Smith Mark | Roberds Steven
Identification of membrane associated drug targets in Borrelia burgdorferi ZS7- subtractive genomics approach

Author(s): Shivkumar Madagi | Vijayakumari Mali Patil | Saremy Sadegh | Abhishek Kumar Singh | Bhavana Garwal | Atreyi Banerjee | Usha Talambedu | Biplab Bhattacharjee
In silico studies on marine actinomycetes as potential inhibitors for Glioblastoma multiforme

Author(s): Palani Kirubakaran | Roopa Kothapalli | Kh. Dhanachandra Singh | Selvaraman Nagamani | Subramanian Arjunan | Karthikeyan Muthusamy
Prediction and analysis of paralogous proteins in Trichomonas vaginalis genome

Author(s): Satendra Singh | Gurmit Singh | Atul Kumar Singh | Budhayash Gautam | Rohit Farmer | Sharad S Lodhi | Gulshan Wadhwa
Database on pharmacophore analysis of active principles, from medicinal plants

Author(s): Daisy Pitchai | Rajalakshmi Manikkam | Gnanamani Pitchai | Sasikala R. Rajendran
Identification and modeling of a drug target for Clostridium perfringens SM101

Author(s): Gagan Chhabra | Avishek Anant | Sachin Deshmukh | Himani Kaushik | Pramila Sharma | Keshav Gopal | Nutan Srivastava | Lalit C. Garg
Genome subtraction for novel target definition in Salmonella typhi

Author(s): Bhawna Rathi | Nidhi Trivedi | Aditya N. Sarangi
Genomic target database (GTD): A database of potential targets in human pathogenic bacteria

Author(s): Debmalya Barh | Anil Kumar | Amarendra Narayana Misra
Putative Biomarkers and Targets of Estrogen Receptor Negative Human Breast Cancer

Author(s): Ziad J. Sahab | Yan-Gao Man | Stephen W. Byers | Qing-Xiang A. Sang
Epigenetic Therapy for Breast Cancer

Author(s): Feng-Feng Cai | Corina Kohler | Bei Zhang | Ming-Hong Wang | Wei-Jie Chen | Xiao-Yan Zhong
A Role for Sigma Receptors in Stimulant Self Administration and Addiction

Author(s): Jonathan L. Katz | Tsung-Ping Su | Takato Hiranita | Teruo Hayashi | Gianluigi Tanda | Theresa Kopajtic | Shang-Yi Tsai
Systematic Approaches towards the Development of Host-Directed Antiviral Therapeutics

Author(s): Andrew Prussia | Pahk Thepchatri | James P. Snyder | Richard K. Plemper
New Generation Novel Drugs Designed For Type 2 Diabetes By Insilico Computational Methods which block IRS4

Author(s): Thanigaivelan 1 | Sampoornam Balakrishnan 2 | Karpagam Veerappan 3 | Rasappan Periannan 4 | Shila Samuel*5
Identification of potential apicoplast associated therapeutic targets in human and animal pathogen Toxoplasma gondii ME49

Author(s): Sadegh Saremy | Biplab Bhattacharjee* | Mahdi Eskandarian Boroujeni | Jhinuk Chatterjee | Viditi Mittal
Inhibition of U6 snRNA Transcription by PTEN

Author(s): Stephanie Cabarcas | Kounosuke Watabe | Laura Schramm
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