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Scaffolding proteins in G-protein signaling

Author(s): Andreeva Alexandra | Kutuzov Mikhail | Voyno-Yasenetskaya Tatyana
Fungal GPCR signaling in pheromone response

Author(s): Kothe E | Erdmann S | Knabe N | Jung E-M
Frequent substructure mining of GPCR ligands

Author(s): Horst E | Bender A | IJzerman AP
The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

Author(s): Pickering Chris | Hägglund Maria | Szmydynger-Chodobska Joanna | Marques Fernanda | Palha Joana | Waller Linn | Chodobski Adam | Fredriksson Robert | Lagerström Malin | Schiöth Helgi
Protean Agonists: A looking glass for GPCR and G Protein function

Author(s): Mr Mahip Kalyan Verma | Dr. Anantha Naik Nagappa
Illuminating the life of GPCRs

Author(s): Böhme Ilka | Beck-Sickinger Annette
Chemical genetics reveals an RGS/G-protein role in the action of a compound.

Author(s): Fitzgerald Kevin | Tertyshnikova Svetlana | Moore Lisa | Bjerke Lynn | Burley Ben | Cao Jian | Carroll Pamela | Choy Robert | Doberstein Steve | Dubaquie Yves | Franke Yvonne | Kopczynski Jenny | Korswagen Hendrik | Krystek Stanley R | Lodge Nicholas J | Plasterk Ronald | Starrett John | Stouch Terry | Thalody George | Wayne Honey | van der Linden Alexander | Zhang Yongmei | Walker Stephen G | Cockett Mark | Wardwell-Swanson Judi | Ross-Macdonald Petra | Kindt Rachel M
On the origins of arrestin and rhodopsin

Author(s): Alvarez Carlos
Homology modeling and docking studies of human G-Protein coupled receptor involved in taste perception

Author(s): Padmavathi G. V. | Nataraj Sekhar P. | Kavi Kishor P. B. | Vishal Kumar Shah A. | Saralakumari D.
GPCRTree: online hierarchical classification of GPCR function

Author(s): Davies Matthew | Secker Andrew | Halling-Brown Mark | Moss David | Freitas Alex | Timmis Jon | Clark Edward | Flower Darren
Endothelin-1, an Endogenous Irreversible Agonist in Search of an Allosteric Inhibitor

Author(s): Jo G.R. De Mey | Matthijs G. Compeer | Merlijn J. Meens
Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists Toward Downsizing

Author(s): Hirokazu Tamamura | Hiroshi Tsutsumi | Wataru Nomura | Nobutaka Fujii
GPCR Conformations: Implications for Rational Drug Design

Author(s): Abby L. Parrill | Debra L. Bautista
Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening

Author(s): Martin Cottet | Orestis Faklaris | Jurriaan M. Zwier | Eric Trinquet | Jean-Philippe Pin | Thierry Durroux
A cell spot microarray method for production of high density siRNA transfection microarrays

Author(s): Rantala Juha | Mäkelä Rami | Aaltola Anna-Riina | Laasola Petra | Mpindi John-Patrick | Nees Matthias | Saviranta Petri | Kallioniemi Olli
Virtual screening of GPCRs: An in silico chemogenomics approach

Author(s): Jacob Laurent | Hoffmann Brice | Stoven Véronique | Vert Jean-Philippe
Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit

Author(s): Di Certo Maria | Batassa Enrico | Casella Ida | Serafino Annalucia | Floridi Aristide | Passananti Claudio | Molinari Paola | Mattei Elisabetta
Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates

Author(s): Klutz Athena | Gao Zhan-Guo | Lloyd John | Shainberg Asher | Jacobson Kenneth
The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Author(s): Haitina Tatjana | Fredriksson Robert | Foord Steven | Schiöth Helgi | Gloriam David
Differential role of beta-arrestin ubiquitination in agonist-promoted down-regulation of M1 vs M2 muscarinic acetylcholine receptors

Author(s): Mosser Valerie | Jones Kymry | Hoffman Katie | McCarty Nael | Jackson Darrell
Evolution of the class C GPCR Venus flytrap modules involved positive selected functional divergence

Author(s): Cao Jianhua | Huang Siluo | Qian Ji | Huang Jinlin | Jin Li | Su Zhixi | Yang Ji | Liu Jianfeng
The repertoire of G-protein-coupled receptors in Xenopus tropicalis

Author(s): Ji Yanping | Zhang Zhen | Hu Yinghe
Luciferase activity under direct ligand-dependent control of a muscarinic acetylcholine receptor

Author(s): Thor Doreen | Le Duc Diana | Strotmann Rainer | Schöneberg Torsten
Gene Expression and Serum Cytokine Profiling of Low Stage CLL Identify WNT/PCP, Flt-3L/Flt-3 and CXCL9/CXCR3 as Regulators of Cell Proliferation, Survival and Migration

Author(s): Daruka Mahadevan | James Choi | Laurence Cooke | Bram Simons | Christopher Riley | Thomas Klinkhammer | Rohit Sud | Sirisha Maddipoti | Sean Hehn | Harinder Garewal | Catherine Spier
7TMRmine: a Web server for hierarchical mining of 7TMR proteins

Author(s): Lu Guoqing | Wang Zhifang | Jones Alan | Moriyama Etsuko
Expression and function of proton-sensing G-protein-coupled receptors in inflammatory pain

Author(s): Chen Ying-Ju | Huang Chia-Wei | Lin Chih-Shin | Chang Wen-Han | Sun Wei-Hsin
Production and characterisation of monoclonal antibodies against RAI3 and its expression in human breast cancer

Author(s): Jörißen Hannah | Bektas Nuran | Dahl Edgar | Hartmann Arndt | ten Haaf Anette | Di Fiore Stefano | Kiefer Hans | Thess Andreas | Barth Stefan | Klockenbring Torsten
Prolonged somatostatin therapy may cause down–regulation of SSTR–like GPCRs on Schistosoma mansoni

Author(s): Shyama Chatterjee | Jeff Op De Beeck | Archana V. Rao | Dattatraya V. Desai | Gunther Vrolix | Frank Rylanta | Thomas Panis | Amit Bernat | Jonathan Van Bergen | Dieter Peeters | Eric Van Marck
Dynamic imaging of cannabinoid receptor 1 vesicular trafficking in cultured astrocytes

Author(s): Kyle D Osborne | William Lee | Erik B Malarkey | Andrew J Irving | Vladimir Parpura
Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid

Author(s): Oyesanya Regina | Greenbaum Susie | Dang David | Lee Zendra | Mukherjee Abir | Wu Jinhua | Dent Paul | Fang Xianjun
Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach

Author(s): Parravicini Chiara | Abbracchio Maria | Fantucci Piercarlo | Ranghino Graziella
Nucleoside conjugates of quantum dots for characterization of G protein-coupled receptors: strategies for immobilizing A2A adenosine receptor agonists

Author(s): Das Arijit | Sanjayan Gangadhar | Kecskés Miklós | Yoo Lena | Gao Zhan-Guo | Jacobson Kenneth
The serendipitous origin of chordate secretin peptide family members

Author(s): Cardoso João | Vieira Florbela | Gomes Ana | Power Deborah
N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

Author(s): McHugh Douglas | Hu Sherry | Rimmerman Neta | Juknat Ana | Vogel Zvi | Walker J Michael | Bradshaw Heather
A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization

Author(s): van der Horst Eelke | Peironcely Julio | IJzerman Adriaan | Beukers Margot | Lane Jonathan | van Vlijmen Herman | Emmerich Michael | Okuno Yasushi | Bender Andreas
A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism

Author(s): Gris Pavel | Gauthier Josee | Cheng Philip | Gibson Dustin | Gris Denis | Laur Oskar | Pierson John | Wentworth Sean | Nackley Andrea | Maixner William | Diatchenko Luda
Role of the G Protein-Coupled Receptor, mGlu1, in Melanoma Development

Author(s): Janet Wangari-Talbot | James Goydos | Suzie Chen
Incidence of Childhood Cancers in Golestan Province of Iran

Author(s): Abdolvahab Moradi | Shahryar Semnani | Gholamreza Roshandel | Narges Mirbehbehani | Abbasali Keshtkar | Mohsen Aarabi | Abbas Moghaddami | Fatemeh Cheraghali
Protein Based Drug Discovery

Author(s): Joshi B. | Gupta G. | Gupta N. | Gupta M. | Trivedi S. | Patil P. | Jhadav A. | Vamsi K.K. | Khairnar Y. | Boraste A. | Mujapara A.
Differential expression of Gs in a murine model of homocysteinemic heart failure

Author(s): Thomas P Vacek | Utpal Sen | Neetu Tyagi | Jonathan C Vacek | Munish Kumar | et al
Dominant negative effect of the extracellular domain of CASR

Author(s): Min Pi | Junhui Chen | Wenyu Zhu | et al
GPCRs Revisited: New Insights Lead to Novel Drugs

Author(s): Richard M. Eglen | Terry Reisine
The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis

Author(s): Braun Benedikt | Slowik Alexander | Leib Stephen | Lucius Ralph | Varoga Deike | Wruck Christoph | Jansen Sandra | Podschun Rainer | Pufe Thomas | Brandenburg Lars-Ove
The G protein-coupled receptors in the pufferfish Takifugu rubripes

Author(s): Sarkar Anita | Kumar Sonu | Sundar Durai
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis

Author(s): Atwood Brady | Lopez Jacqueline | Wager-Miller James | Mackie Ken | Straiker Alex
Soft X-ray Laser Microscopy of Lipid Rafts towards GPCR-Based Drug Discovery Using Time-Resolved FRET Spectroscopy

Author(s): Motoyoshi Baba | Tohru Kozasa | Takao Hamakubo | Hiroto Kuroda | Kazuyuki Masuda | Shin Yoneya | Tatsuhiko Kodama
Molecular Approaches To Target GPCRs in Cancer Therapy

Author(s): Giulio Innamorati | Maria Teresa Valenti | Francesco Giovinazzo | Luca Dalle Carbonare | Marco Parenti | Claudio Bassi
Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase

Author(s): Hurley Joyce | Zhang Shengwen | Bye Leighan | Marshall Mark | DePaoli-Roach Anna | Guan Kunliang | Fox Aaron | Yu Lei
Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils

Author(s): Bylund Johan | Pellmé Sara | Fu Huamei | Mellqvist Ulf-Henrik | Hellstrand Kristoffer | Karlsson Anna | Dahlgren Claes
A database for G proteins and their interaction with GPCRs

Author(s): Elefsinioti Antigoni | Bagos Pantelis | Spyropoulos Ioannis | Hamodrakas Stavros
Identification of functional SNPs in the 5-prime flanking sequences of human genes

Author(s): Mottagui-Tabar Salim | Faghihi Mohammad | Mizuno Yosuke | Engström Pär | Lenhard Boris | Wasserman Wyeth | Wahlestedt Claes
Tre1, a G Protein-Coupled Receptor, Directs Transepithelial Migration of Drosophila Germ Cells

Author(s): Kunwar Prabhat S | Starz-Gaiano Michelle | Bainton Roland J | Heberlein Ulrike | Lehmann Ruth
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models

Author(s): Sgourakis Nikolaos | Bagos Pantelis | Papasaikas Panagiotis | Hamodrakas Stavros
S-Nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner

Author(s): Kokkola Tarja | Savinainen Juha | Mönkkönen Kati | Retamal Montse | Laitinen Jarmo
Genome wide survey of G protein-coupled receptors in Tetraodon nigroviridis

Author(s): Metpally Raghu | Sowdhamini Ramanathan
Human Latrophilin-2 is Expressed in the Cytotrophoblast and Syncytiotrophoblast of Placenta and in Endothelial Cells

Author(s): Gunda Herberth, | Anke Stein, | Stefan Taudien, | Irina Klaman, | Alexander Herr | Jens Glienke, Karl-Heinz Thierauch and Anette Sommer
Expression of mammalian GPCRs in C. elegans generates novel behavioural responses to human ligands

Author(s): Teng Michelle | Dekkers Martijn | Ng Bee | Rademakers Suzanne | Jansen Gert | Fraser Andrew | McCafferty John
RINGdb: An integrated database for G protein-coupled receptors and regulators of G protein signaling

Author(s): Fang Yu-Ching | Sun Wei-Hsin | Wu Li-Cheng | Huang Hsien-Da | Juan Hsueh-Fen | Horng Jorng-Tzong
Evolution of secretin family GPCR members in the metazoa

Author(s): Cardoso João | Pinto Vanda | Vieira Florbela | Clark Melody | Power Deborah
GrlJ, a Dictyostelium GABAB-like receptor with roles in post-aggregation development

Author(s): Prabhu Yogikala | Müller Rolf | Anjard Christophe | Noegel Angelika
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base

Author(s): Skrabanek Lucy | Murcia Marta | Bouvier Michel | Devi Lakshmi | George Susan | Lohse Martin | Milligan Graeme | Neubig Richard | Palczewski Krzysztof | Parmentier Marc | Pin Jean-Philippe | Vriend Gerrit | Javitch Jonathan | Campagne Fabien | Filizola Marta
R7-binding protein targets the G protein β5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain

Author(s): Nini Lylia | Waheed Abdul | Panicker Leelamma | Czapiga Meggan | Zhang Jian-Hua | Simonds William
The G protein-coupled receptor subset of the rat genome

Author(s): Gloriam David | Fredriksson Robert | Schiöth Helgi
The effect of deletion of the orphan G – protein coupled receptor (GPCR) gene MrgE on pain-like behaviours in mice

Author(s): Cox Peter | Pitcher Tom | Trim Steven | Bell Christine | Qin Wenning | Kinloch Ross
Modelling the structures of G protein-coupled receptors aided by three-dimensional validation

Author(s): Dastmalchi Siavoush | Church W Bret | Morris Michael
Receptor-Drug Interaction: Europium Employment for Studying the Biochemical Pathway of G-Protein-Coupled Receptor Activation

Author(s): Colabufo Nicola Antonio | Perrone Maria Grazia | Contino Marialessandra | Berardi Francesco | Perrone Roberto
The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis

Author(s): Kamesh N | Aradhyam Gopala | Manoj Narayanan
Expression analysis of G Protein-Coupled Receptors in mouse macrophages

Author(s): Lattin Jane | Schroder Kate | Su Andrew | Walker John | Zhang Jie | Wiltshire Tim | Saijo Kaoru | Glass Christopher | Hume David | Kellie Stuart | Sweet Matthew
Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

Author(s): Haitina Tatjana | Olsson Fredrik | Stephansson Olga | Alsiö Johan | Roman Erika | Ebendal Ted | Schiöth Helgi | Fredriksson Robert
A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus

Author(s): Shimizu Nobuaki | Tanaka Atsushi | Mori Takahisa | Ohtsuki Takahiro | Hoque Aliful | Jinno-Oue Atsushi | Apichartpiyakul Chatchawann | Kusagawa Shigeru | Takebe Yutaka | Hoshino Hiroo
Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium

Author(s): Sillo Alessio | Bloomfield Gareth | Balest Alessandra | Balbo Alessandra | Pergolizzi Barbara | Peracino Barbara | Skelton Jason | Ivens Alasdair | Bozzaro Salvatore
GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice

Author(s): Li Longxuan | Liu Jun | Suo William
The GHS-R Blocker D-[Lys3] GHRP-6 Serves as CCR5 Chemokine Receptor Antagonist

Author(s): Kalpesh Patel, Vishwa Deep Dixit, Jun Ho Lee, Jie Wan Kim, Eric M. Schaffer, Dzung Nguyen, Dennis D. Taub
Incidence of Childhood Cancers in Golestan Province of Iran

Author(s): Abdolvahab Moradi | Shahryar Semnani | Gholamreza Roshandel | Narges Mirbehbehani | Abbasali Keshtkar | Mohsen Aarabi | Abbas Moghaddami | Fatemeh Cheraghali
G-protein Coupled Receptor Dimerization

Author(s): Nikzad Nikbin | Christine Edwards | Christopher A Reynolds
Molecular evolution of a chordate specific family of G protein-coupled receptors

Author(s): Kurtenbach Stefan | Mayer Christoph | Pelz Thomas | Hatt Hanns | Leese Florian | Neuhaus Eva
Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

Author(s): Aslan Joseph | Spencer Alex | Loren Cassandra | Pang Jiaqing | Welch Heidi | Greenberg Daniel | McCarty Owen
Integrating GPCR-specific information with full text articles

Author(s): Vroling Bas | Thorne David | McDermott Philip | Attwood Teresa | Vriend Gert | Pettifer Steve
Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells

Author(s): Jennen Danyel | Ruiz-Aracama Ainhoa | Magkoufopoulou Christina | Peijnenburg Ad | Lommen Arjen | van Delft Joost | Kleinjans Jos
TM-MOTIF: an alignment viewer to annotate predicted transmembrane helices and conserved motifs in aligned set of sequences

Author(s): Balasubramanian Nagarathnam | Kannan Sankar | Varadhan Dharnidharka | Veluchamy Balakrishnan | Govindaraju Archunan | Ramanathan Sowdhamini*
Mutation of the histidin residue of the DRH motif in vasopressin V2 receptor expression and function

Author(s): H Mir Mohammad Sadeghi | M Rabbani | A Jafarian | H Najafzadeh | L Safaeian
RFamide Peptides: Structure, Function, Mechanisms and Pharmaceutical Potential

Author(s): Maria Findeisen | Daniel Rathmann | Annette G. Beck-Sickinger
In Silico Veritas: The Pitfalls and Challenges of Predicting GPCR-Ligand Interactions

Author(s): Luc Roumen | Marijn P.A. Sanders | Bas Vroling | Iwan J.P. De Esch | Jacob De Vlieg | Rob Leurs | Jan P.G. Klomp | Sander B. Nabuurs | Chris De Graaf
Insights from the analysis of conserved motifs and permitted amino acid exchanges in the human, the fly and the worm GPCR clusters

Author(s): Balasubramanian Nagarathnam | Sankar Kannan | Varadhan Dharnidharka | Veluchamy Balakrishnan | Govindaraju Archunan | Ramanathan Sowdhamini*
Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2

Author(s): Lam Hoa | Maga Matthew | Pradhan Amynah | Evans Christopher | Maidment Nigel | Hales Tim | Walwyn Wendy
Differential regulation of diacylglycerol kinase isoform in human failing hearts

Author(s): Bilim Olga | Shishido Tetsuro | Toyama Shuji | Suzuki Satoshi | Sasaki Toshiki | Kitahara Tatsuro | Sadahiro Mitsuaki | Takeishi Yasuchika | Kubota Isao
Genome-wide profiling of G protein-coupled receptors in cerebellar granule neurons using high-throughput, real-time PCR

Author(s): Maurel Benjamin | Le Digarcher Anne | Dantec Christelle | Journot Laurent
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models

Author(s): Worth Catherine | Kreuchwig Annika | Kleinau Gunnar | Krause Gerd
Cell-free synthesis of a functional G protein-coupled receptor complexed with nanometer scale bilayer discs

Author(s): Yang Jian-Ping | Cirico Tatiana | Katzen Federico | Peterson Todd | Kudlicki Wieslaw
A model for the evaluation of domain based classification of GPCR

Author(s): Tannu Kumari | Bhaskar Pant | Kamalraj R. Pardasani
Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer

Author(s): Carmen Berasain | María Ujue Latasa | Raquel Urtasun | Saioa Goñi | María Elizalde | Oihane Garcia-Irigoyen | María Azcona | Jesús Prieto | Matías A. Ávila
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