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Evaluation of Efficacy of Gefitinib on Advanced non-small-cell Lung Cancer (NSCLC) Resisted to Chemotherapy

Author(s): Mafei KANG | Zhengxu YANG | Ying LIU | Zhaolin MENG | Meiqing LUO | Jiangjiang TU
EGFR Mutations Detection in Non-small Cell Lung Cancer Tissues by Real-time PCR and DNA Sequencing

Author(s): Yongwen LI | Hongyu LIU | Ying LI | Yuli WANG | Jing WANG | Jun CHEN | Qinghua ZHOU
Association between gefitinib and hemorrhagic cystitis and severely contracted bladder: a case report

Author(s): Arakawa Maki | Nakamura Kogenta | Yamada Yoshiaki | Rosser Charles | Tobiume Motoi | Saito Hiroko | Hasegawa Takaaki | Honda Nobuaki
In-silico Interaction Studies of Quinazoline Derivatives for their Inhibitory Action on Both Wild and Mutant EGFRs

Author(s): Kaushik S. Hatti | V. Chandregowda | G.Venkateswara Rao | Anil Kush | G.Chandrasekara Reddy
Analysis of Prognostic Factors of 80 Advanced NSCLC Patients Treated with Gefitinib for more than 6 Months

Author(s): Ling DAI | Jian FANG | Jun NIE | Weiheng HU | Xiaoling CHEN | Jindi HAN | Guangming TIAN | Sen HAN | Xuyi LIU
Good Response to Gefitinib for Lung Adenocarcinoma with Hyperamylasemia: A Case Report

Author(s): How-Wen Ko | Ying-Huang Tsai | Chih-Teng Yu | Chun-Yao Huang | Chih-Hung Chen
Anaplastic thyroid carcinoma: A comprehensive review of current and future therapeutic options

Author(s): Francesco Perri, Giuseppe Di Lorenzo, Giuseppina Della Vittoria Scarpati, Carlo Buonerba
Optimizing response to gefitinib in the treatment of non-small-cell lung cancer

Author(s): Pietro Carotenuto | Cristin Roma | Anna Maria Rachiglio | et al
KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib

Author(s): Pao William | Wang Theresa Y | Riely Gregory J | Miller Vincent A | Pan Qiulu | Ladanyi Marc | Zakowski Maureen F | Heelan Robert T | Kris Mark G | Varmus Harold E
Synthesis of Gefitinibfrom Methyl 3-Hydroxy-4-methoxy-benzoate

Author(s): Ming Dong Li | You Guang Zheng | Min Ji
Relationship between Mutations of the Epidermal Growth Factor Receptor Gene and Drug-Resistance to Gefitinib in Human Lung Cancer in vitro

Author(s): Wei WEI | Yu FAN | Hongyu LIU | Zhihao WU | Haisu WAN | Zhiqin YAN | Ke XU | Qinghua ZHOU
Gefitinib in Advanced Non-small-cell Lung Cancer

Author(s): Lina ZHU | Zhenjun YANG | Shiyong WANG
Synthesis of Gefitinibfrom Methyl 3-Hydroxy-4-methoxy-benzoate

Author(s): Ming Dong Li | You Guang Zheng | Min Ji
Emerging role of gefitinib in the treatment of non-small-cell lung cancer (NSCLC)

Author(s): M Tiseo | M Bartolotti | F Gelsomino | et al
Management of patients with advanced non-small cell lung cancer: role of gefitinib

Author(s): Vamsidhar Velcheti | Daniel Morgensztern | Ramaswamy Govindan
Screening for EGFR Mutations in Patients with Head and Neck Cancer Treated with Gefitinib on a Compassionate-Use Program: A Hellenic Cooperative Oncology Group Study

Author(s): Samuel Murray | Mattheos Bobos | Nikolaos Angouridakis | Angelos Nikolaou | Helena Linardou | Evangelia Razis | George Fountzilas
The effects of DNA formulation and administration route on cancer therapeutic efficacy with xenogenic EGFR DNA vaccine in a lung cancer animal model

Author(s): Lai Ming-Derg | Yen Meng-Chi | Lin Chiu-Mei | Tu Cheng-Fen | Wang Chun-Chin | Lin Pei-Shan | Yang Huei-Jiun | Lin Chi-Chen
Radical cyberknife radiosurgery with tumor tracking: an effective treatment for inoperable small peripheral stage I non-small cell lung cancer

Author(s): Collins Brian | Vahdat Saloomeh | Erickson Kelly | Collins Sean | Suy Simeng | Yu Xia | Zhang Ying | Subramaniam Deepa | Reichner Cristina | Sarikaya Ismet | Esposito Giuseppe | Yousefi Shadi | Jamis-Dow Carlos | Banovac Filip | Anderson Eric
Analysis of Differentially Expressed Proteins in Self-Paired Sera of Advanced Non-small Cell Lung Cancer Patients Responsive to Gefin

Author(s): Xuening YANG | Xuchao ZHANG | Jinji YANG | Yujuan HUANG | Ailin GUO | Jiaying LIN | Shejuan AN | Hongyan TANG | Shiliang CHEN | Ying HUANG | Yilong WU
Interstitial lung disease in gefitinib-treated Japanese patients with non-small cell lung cancer – a retrospective analysis: JMTO LC03-02

Author(s): Nakagawa Masatsugu | Nishimura Tsutomu | Teramukai Satoshi | Tada Harue | Tanaka Fumihiro | Yanagihara Kazuhiro | Furuse Kiyoyuki | Wada Hiromi | Fukushima Masanori
Response to gefitinib and erlotinib in Non-small cell lung cancer: a retrospective study

Author(s): Emery Ivette | Battelli Chiara | Auclair Paul | Carrier Kathleen | Hayes Daniel
The drug-resistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro

Author(s): Zhuang Hong-Qing | Wang Jun | Yuan Zhi-Yong | Zhao Lu-Jun | Wang Ping | Wang Chang-Li
Application of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor as the First-line Therapy in Patients with Advanced Non-small Cell Lung Cancer

Author(s): Yang XU | Liang’an CHEN | Qing TIAN | Zhen YANG | Wei ZHAO | Ping WANG | Xingchen LIU | Chunsun LI
Synergistic effect of gefitinib and rofecoxib in mesothelioma cells

Author(s): Stoppoloni Daniela | Canino Claudia | Cardillo Irene | Verdina Alessandra | Baldi Alfonso | Sacchi Ada | Galati Rossella
Hemorrhage of brain metastasis from non-small cell lung cancer post gefitinib therapy: two case reports and review of the literature

Author(s): Yan Dan-Fang | Yan Sen-Xiang | Yang Jing-Song | Wang Yi-Xiang | Sun Xiao-Li | Liao Xin-Biao | Liu Jun-Qing
Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer model

Author(s): Diaz Roque | Nguewa Paul | Parrondo Ricardo | Perez-Stable Carlos | Manrique Irene | Redrado Miriam | Catena Raul | Collantes Maria | Peñuelas Ivan | Díaz-González Juan | Calvo Alfonso
EGFR isoforms and gene regulation in human endometrial cancer cells

Author(s): Albitar Lina | Pickett Gavin | Morgan Marilee | Wilken Jason | Maihle Nita | Leslie Kimberly
First-line single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer

Author(s): Yin Yong-Mei | Geng Yi-Ting | Shao Yong-Feng | Hu Xiao-Li | Li Wei | Shu Yong-Qian | Wang Zhao-Xia
Targeting of Both the c-Met and EGFR Pathways Results in Additive Inhibition of Lung Tumorigenesis in Transgenic Mice

Author(s): Laura P. Stabile | Mary E. Rothstein | Phouthone Keohavong | Diana Lenzner | Stephanie R. Land | Autumn L. Gaither-Davis | K. Jin Kim | Naftali Kaminski | Jill M. Siegfried
Erlotinib-associated Near-fatal Interstitial Pneumonitis in A Patient with Relapsed Lung Adenocarcinoma

Author(s): Chun-Liang Chou | How-Wen Ko | Chih-Wei Wang | Chih-Teng Yu | Han-Pin Kuo | Chien-Da Huang
Geftinib

Author(s): Gupta Ajay | Raina Vinod
Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer

Author(s): Peraldo-Neia Caterina | Migliardi Giorgia | Mello-Grand Maurizia | Montemurro Filippo | Segir Raffaella | Pignochino Ymera | Cavalloni Giuliana | Torchio Bruno | Mosso Luciano | Chiorino Giovanna | Aglietta Massimo
Molecular mechanism of the schedule-dependent synergistic interaction in EGFR-mutant non-small cell lung cancer cell lines treated with paclitaxel and gefitinib

Author(s): Cheng Hua | An She-Juan | Dong Song | Zhang Yi-Fang | Zhang Xu-Chao | Chen Zhi-Hong | Jian-Su | Wu Yi-Long
Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysis

Author(s): Watanabe Satoshi | Tanaka Junta | Ota Takeshi | Kondo Rie | Tanaka Hiroshi | Kagamu Hiroshi | Ichikawa Kosuke | Koshio Jun | Baba Junko | Miyabayashi Takao | Narita Ichiei | Yoshizawa Hirohisa
Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

Author(s): Pignochino Ymera | Sarotto Ivana | Peraldo-Neia Caterina | Penachioni Junia | Cavalloni Giuliana | Migliardi Giorgia | Casorzo Laura | Chiorino Giovanna | Risio Mauro | Bardelli Alberto | Aglietta Massimo | Leone Francesco
Current approach in the treatment of hepatocellular carcinoma

Author(s): Luigi Rossi | Federica Zoratto | Anselmo Papa | Francesca Iodice | Marina Minozzi | Luigi Frati | Silverio Tomao
Epidermal Growth Factor Receptor Mutations in Cells from Non-Small Cell Lung Cancer Malignant Pleural Effusions

Author(s): Ming-Szu Hung | Chin-Kuo Lin | Shaw-Wei Leu | Mei-Yi Wu | Ying-Huang Tsai | Cheng-Ta Yang
Retreatment with Epidermal Growth Factor Receptor Inhibitor After Initial Failure in Advanced Non-small Cell Lung Cancer

Author(s): Tongtong AN | Zhen HUANG | Yuyan WANG | Zhijie WANG | Hua BAI | Jie WANG
Gefitinib for Non-small Cell Lung Cancer: A meta Analysis

Author(s): Jiwu GUO | Bin MA | Huiyin ZHOU | Yao WANG | Yuan ZHANG
Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity

Author(s): Naruo Yoshimi | Nagashima Takeshi | Ushikoshi-Nakayama Ryoko | Saeki Yuko | Nakakuki Takashi | Naka Takashi | Tanaka Hiroshi | Tsai Shih-Feng | Okada-Hatakeyama Mariko
Successful treatment of persistent bronchorrhea by gefitinib in a case with Recurrent Bronchioloalveolar Carcinoma: a case report

Author(s): Takao Motoshi | Inoue Kentarou | Watanabe Fumiaki | Onoda Koji | Shimono Takatsugu | Shimpo Hideto | Yada Isao
Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain

Author(s): Pao William | Miller Vincent A | Politi Katerina A | Riely Gregory J | Somwar Romel | Zakowski Maureen F | Kris Mark G | Varmus Harold
A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma

Author(s): Bekaii-Saab Tanios | Williams Nita | Plass Christoph | Calero Miguel | Eng Charis
Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulation

Author(s): Noro Rintaro | Gemma Akihiko | Kosaihira Seiji | Kokubo Yutaka | Chen Mingwei | Seike Masahiro | Kataoka Kiyoko | Matsuda Kuniko | Okano Tetsuya | Minegishi Yuji | Yoshimura Akinobu | Kudoh Shoji
Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer

Author(s): Yokouchi Hiroshi | Yamazaki Koichi | Kinoshita Ichiro | Konishi Jun | Asahina Hajime | Sukoh Noriaki | Harada Masao | Akie Kenji | Ogura Shigeaki | Ishida Takashi | Munakata Mitsuru | Dosaka-Akita Hirotoshi | Isobe Hiroshi | Nishimura Masaharu
Correlations of EGFR mutations and increases in EGFR and HER2 copy number to gefitinib response in a retrospective analysis of lung cancer patients

Author(s): Pugh Trevor | Bebb Gwyn | Barclay Lorena | Sutcliffe Margaret | Fee John | Salski Chris | O'Connor Robert | Ho Cheryl | Murray Nevin | Melosky Barbara | English John | Vielkind Jeurgen | Horsman Doug | Laskin Janessa | Marra Marco
Functional analysis of cancer-associated EGFR mutants using a cellular assay with YFP-tagged EGFR intracellular domain

Author(s): de Gunst Matheus | Gallegos-Ruiz Marielle | Giaccone Giuseppe | Rodriguez Jose
Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral lung tumors

Author(s): Collins Brian | Erickson Kelly | Reichner Cristina | Collins Sean | Gagnon Gregory | Dieterich Sonja | McRae Don | Zhang Ying | Yousefi Shadi | Levy Elliot | Chang Thomas | Jamis-Dow Carlos | Banovac Filip | Anderson Eric
Defective Differentiation of Myeloid and Plasmacytoid Dendritic Cells in Advanced Cancer Patients is not Normalized by Tyrosine Kinase Inhibition of the Vascular Endothelial Growth Factor Receptor

Author(s): H. van Cruijsen | K. Hoekman | A. G. M. Stam | A. J. M. van den Eertwegh | B. C. Kuenen | R. J. Scheper | G. Giaccone | T. D. de Gruijl
Gefitinib for patients with advanced non-small cell lung cancer treated on the expanded access program: a single institution experience

Author(s): Marcelo Rocha de Souza Cruz | Artur Katz | Rene Claudio Gansl | Jacques Tabacoff | Oren Smaletz | Sergio Daniel Simon
Clinic outcome of gefitinib in sixty-nine elderly patients with lung adenocarcinoma

Author(s): Yan WANG | Xiangru ZHANG | Bin WANG | Ziping WANG | Datong CHU | Yan SUN
The Relationship between EGFR Mutations and Response and Prognosis of Tyrosine Kinase Inhibitors in Advanced Non-small-cell Lung Cancer

Author(s): Xinyong ZHANG | Liyan XU | Hui WANG | Yunzhong ZHU | Zhe LIU | Wentao YUE | Junfang TANG | Wei WU | Zan LIU | Yuhua WU | Chunyan ZHANG | Yuankai SHI | Mengzhao WANG | Heling SHI | Mingzhi LI | Qiyi MENG | Lili GUO | Jinghui WANG | Xuebing LI
Clinical Response of Gefitinib on Malignant Pleural Effusions in Patients with Non-Small Cell Lung Cancer

Author(s): Chi-Hsien Chen | Chien-Hung Gow | Chong-Jen Yu | Jin-Yuan Shih | Ya-Chieh Hsu | Wen-Yu Lee | Pan-Chyr Yang | Sow-Hsong Kuo
Analysis of Cytotoxic Effects of Chemotherapeutic Agents on Lung and Small Intestinal Neuroendocrine Cell Lines

Author(s): Jan Bornschein | Mark Kidd | Maximilian V. Malfertheiner | Ignat Drozdov | Roswitha Pfragner | Irvin M. Modlin
Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines

Author(s): Solmi Rossella | Lauriola Mattia | Francesconi Mirko | Martini Désirée | Voltattorni Manuela | Ceccarelli Claudio | Ugolini Giampaolo | Rosati Giancarlo | Zanotti Simone | Montroni Isacco | Mattei Gabriella | Taffurelli Mario | Santini Donatella | Pezzetti Furio | Ruggeri Alessandro | Castellani Gastone | Guidotti Lia | Coppola Domenico | Strippoli Pierluigi
Successful Erlotinib Treatment for a Patient with Gefitinib-Related Hepatotoxicity and Lung Adenocarcinoma Refractory to Intermittently Administered Gefitinib

Author(s): Tatsuya Nagano | Yoshikazu Kotani | Kazuyuki Kobayashi | Masahiro Katsurada | Yukihisa Hatakeyama | Suya Hori | Daisuke Tamura | Daisuke Kasai | Yasuhiro Funada | Yoshihiro Nishimura
EGFR as a therapeutic target in glioblastoma

Author(s): David M Siebert | Sophia F Shakur | Peter Pytel | Lukas Rimas
Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing

Author(s): Borràs Emma | Jurado Ismael | Hernan Imma | Gamundi María | Dias Miguel | Martí Isabel | Mañé Begoña | Arcusa Àngels | Agúndez José | Blanca Miguel | Carballo Miguel
Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells

Author(s): Müller Kristin | Tveteraas Ingun | Aasrum Monica | Ødegård John | Dawood Mona | Dajani Olav | Christoffersen Thoralf | Sandnes Dagny
The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity

Author(s): Dragowska Wieslawa | Weppler Sherry | Qadir Mohammed | Wong Ling | Franssen Yannick | Baker Jennifer | Kapanen Anita | Kierkels Guido | Masin Dana | Minchinton Andrew | Gelmon Karen | Bally Marcel
Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies

Author(s): Ramon Andrade de Mello | Dânia Sofia Marques | Rui Medeiros | António MF Araújo
Pemetrexed Alone versus Pemetrexed Combined with Oxaliplatin as Salvage Therapy 
in Stage IV Lung Adenocarcinoma

Author(s): Youru LIU | Yinling JIANG | Zhiqiang GAO | Xiangying WANG | Baohui HAN | Liyan JIANG
Gefitinib in Non Small Cell Lung Cancer

Author(s): Raffaele Costanzo | Maria Carmela Piccirillo | Claudia Sandomenico | Guido Carillio | Agnese Montanino | Gennaro Daniele | Pasqualina Giordano | Jane Bryce | Gianfranco De Feo | Massimo Di Maio | Gaetano Rocco | Nicola Normanno | Francesco Perrone | Alessandro Morabito
Pyrosequencing, a method approved to detect the two major EGFR mutations for anti EGFR therapy in NSCLC

Author(s): Dufort Sandrine | Richard Marie-Jeanne | Lantuejoul Sylvie | de Fraipont Florence
Identification of Degradant Impurity in Gefitinib by Using Validated RRLC Method

Author(s): Madireddy Venkataramanna | Indukuri Venkata Somaraju | Kondra Sudhakar Babu
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