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Design, Synthesis and Anti-HIV Integrase Evaluation of 4-Oxo-4H-quinolizine-3-carboxylic Acid Derivatives

Author(s): Yi-Sheng Xu | Cheng-Chu Zeng | Zi-Guo Jiao | Li-Ming Hu | Ru-gang Zhong
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Author(s): Serrao Erik | Odde Srinivas | Ramkumar Kavya | Neamati Nouri
Comparative biochemical analysis of wildtype and drug resistant HIV-1 integrase subtypes B and C

Author(s): Bar-Magen Tamara | Sloan Richard | McDonough Emily | Faltenbacher Verena | Donahue D Aaron | Kuhl Bjorn | Xu Hongtao | Wainberg Mark
Design, Synthesis and Anti-HIV Integrase Evaluation of N-(5-Chloro-8-Hydroxy-2-Styrylquinolin-7-yl)Benzenesulfonamide Derivatives

Author(s): Zi-Guo Jiao | Hong-Qiu He | Cheng-Chu Zeng | Jian-Jun Tan | Li-Ming Hu | Cun-Xin Wang
Anti - HIV-1 integrase activity of Thai Medicinal Plants

Author(s): Kingkan Bunluepuech | Supinya Tewtrakul
Raltegravir in the management of HIV-infected patients

Author(s): Hans-Jürgen Stellbrink
Patterns of resistance development with integrase inhibitors in HIV

Author(s): Jean L Mbisa | Supang A Martin | Patricia A Cane
Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors

Author(s): I. Kostova | S. Raleva | P. Genova | R. Argirova
Inibidores da HIV-integrase: potencial abordagem farmacológica para tratamento da AIDS

Author(s): Melo Eduardo Borges de | Bruni Aline Thaís | Ferreira Márcia Miguel Castro
The integrase interactor 1 (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription

Author(s): Ariumi Yasuo | Serhan Fatima | Turelli Priscilla | Telenti Amalio | Trono Didier
AIDS: A review of targets and approaches for treatment

Author(s): Gupta S | Ramteke Suman | Gupta A | Moorthy N.S.H.N
Anti-HIV-1 integrase activity of medicinal plants used as self medication by AIDS patients

Author(s): Supinya Tewtrakul | Sanan Subhadhirasakul | Sopa Kummee
6th International Symposium on Retroviral Nucleocapsid

Author(s): Berkhout Ben | Gorelick Robert | Summers Michael | Mély Yves | Darlix Jean-Luc
Natural variation of HIV-1 group M integrase: Implications for a new class of antiretroviral inhibitors

Author(s): Rhee Soo-Yon | Liu Tommy | Kiuchi Mark | Zioni Rafael | Gifford Robert | Holmes Susan | Shafer Robert
Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid

Author(s): Mario Sechi | Fabio Casu | Ilaria Campesi | Stefano Fiori | Alberto Mariani
Design and Synthesis of Bis-amide and Hydrazide-containing Derivatives of Malonic Acid as Potential HIV-1 Integrase Inhibitors

Author(s): Mario Sechi | Ugo Azzena | Maria Paola Delussu | Roberto Dallocchio | Alessandro Dessì | Alessia Cosseddu | Nicolino Pala | Nouri Neamati
Drug Profile Of Raltegravir - An Integrase Iinhibitor

Author(s): M.Sathish | P.G. Sunitha | R.Priyadharsini
HIV-1 integrase polymorphisms are associated with prior antiretroviral drug exposure

Author(s): van Hal Sebastiaan | Herring Belinda | Deris Zaquan | Wang Bin | Saksena Nitin | Dwyer Dominic
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Author(s): Serrao Erik | Odde Srinivas | Ramkumar Kavya | Neamati Nouri
Synthesis, antiinflammatory and HIV-1 integrase inhibitory activities of 1,2-bis[5-thiazolyl]ethane-1,2-dione derivatives

Author(s): Franklin P | Yerande S | Thakar H | Inamdar G | Giri R | Padh H | Sudarsanam V | Vasu Kamala
HIV-1 acetylated integrase is targeted by KAP1 (TRIM28) to inhibit viral integration

Author(s): Allouch Awatef | Liverani Vania | Arosio Daniele | Gutierrez Maria | Lusic Marina | Galli Alvaro | Giacca Mauro | Cereseto Anna
GCN5-dependent acetylation of HIV-1 integrase enhances viral integration

Author(s): Terreni Mariaelena | Liverani Vania | Gutierrez Maria | Di Primio Cristina | Di Fenza Armida | Tozzini Valentina | Albanese Alberto | Arosio Daniele | Giacca Mauro | Cereseto Anna
P09-11. Reduced replication capacity of NL4-3 chimeric viruses encoding RT-Integrase sequences from HIV-1 elite controllers

Author(s): Li C | Brumme ZL | Miura T | Rosato PC | Sela J | Brumme CJ | Heckerman D | Pereyra F | Walker BD | Brockman MA
Reverse Transcriptase and Cellular Factors: Regulators of HIV-1 Reverse Transcription

Author(s): Kylie Warren | David Warrilow | Luke Meredith | David Harrich
HIV-1 Integrase-DNA Recognition Mechanisms

Author(s): Jacques J. Kessl | Christopher J. McKee | Jocelyn O. Eidahl | Nikolozi Shkriabai | Ari Katz | Mamuka Kvaratskhelia
Comparative biochemical analysis of HIV-1 subtype B and C integrase enzymes

Author(s): Bar-Magen Tamara | Sloan Richard | Faltenbacher Verena | Donahue Daniel | Kuhl Björn | Oliveira Maureen | Xu Hongtao | Wainberg Mark
Changes in the accessibility of the HIV-1 Integrase C-terminus in the presence of cellular proteins

Author(s): Benkhelifa-Ziyyat Sofia | Bucher Stéphanie | Zanta-Boussif Maria-Antonietta | Pasquet Julie | Danos Olivier
Resistance to Integrase Inhibitors

Author(s): Mathieu Métifiot | Christophe Marchand | Kasthuraiah Maddali | Yves Pommier
A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors

Author(s): Smith Johanna | Yeung Jennifer | Kao Gary | Daniel René
Raltegravir: first in class HIV integrase inhibitor

Author(s): Zelalem Temesgen | Dawd S Siraj
Genomic insertion of lentiviral DNA circles directed by the yeast Flp recombinase

Author(s): Moldt Brian | Staunstrup Nicklas | Jakobsen Maria | Yáñez-Muñoz Rafael | Mikkelsen Jacob
Contribution of the C-terminal region within the catalytic core domain of HIV-1 integrase to yeast lethality, chromatin binding and viral replication

Author(s): Xu Zaikun | Zheng Yingfeng | Ao Zhujun | Clement Martin | Mouland Andrew | Kalpana Ganjam | Belhumeur Pierre | Cohen Éric | Yao XiaoJian
Integrase and integration: biochemical activities of HIV-1 integrase

Author(s): Delelis Olivier | Carayon Kevin | Saïb Ali | Deprez Eric | Mouscadet Jean-François
Design, synthesis and antiHIV activity of novel isatine-sulphonamides

Author(s): Murugesh N | Chandramohan M | Debyser Z | Witvrouw M | Selvam P
HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome

Author(s): Zaitseva Lyubov | Cherepanov Peter | Leyens Lada | Wilson Sam | Rasaiyaah Jane | Fassati Ariberto
Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

Author(s): Dar Mohd | Monel Blandine | Krishnan Lavanya | Shun Ming-Chieh | Di Nunzio Francesca | Helland Dag | Engelman Alan
DNA double strand break repair enzymes function at multiple steps in retroviral infection

Author(s): Sakurai Yasuteru | Komatsu Kenshi | Agematsu Kazunaga | Matsuoka Masao
Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal

Author(s): Levin Aviad | Armon-Omer Ayelet | Rosenbluh Joseph | Melamed-Book Naomi | Graessmann Adolf | Waigmann Elisabeth | Loyter Abraham
Modelación molecular y variación estructural de las integrasas de dos retrovirus humanos: HTLV-I y VIH-1 / Molecular Modeling and Structural Variation of two Human Retrovirus Integrases: HTLV-I and HIV-1

Author(s): Felipe García Vallejo | Yesid Cuesta Astroz | Martha C. Domínguez | Adalberto Sánchez | Mercedes Salcedo Cifuentes | Diane María Díaz | Milton Quintana
Retroviral Integration Site Selection

Author(s): Sébastien Desfarges | Angela Ciuffi
The Anti-HIV Actions of 7- and 10-Substituted Camptothecins

Author(s): Yu-Ye Li | Shi-Wu Chen | Liu-Meng Yang | Rui-Rui Wang | Wei Pang | Yong-Tang Zheng
Designing a non-virulent HIV-1 strain: potential implications for vaccine

Author(s): Abbas Rezaei | Rezvan Zabihollahi | Mansoor Salehi | Sharareh Moghim | Hasan Tamizifar | Nasrin Yazdanpanahi | Gilda Amini
Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptases

Author(s): Hartl Maximilian | Mayr Florian | Rethwilm Axel | Wöhrl Birgitta
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

Author(s): Lewis Mark | Norelli Sandro | Collins Matt | Barreca Maria | Iraci Nunzio | Chirullo Barbara | Yalley-Ogunro Jake | Greenhouse Jack | Titti Fausto | Garaci Enrico | Savarino Andrea
GCN5-dependent acetylation of HIV-1 integrase enhances viral integration

Author(s): Terreni Mariaelena | Valentini Paola | Liverani Vania | Gutierrez Maria | Di Primio Cristina | Di Fenza Armida | Tozzini Valentina | Allouch Awatef | Albanese Alberto | Giacca Mauro | Cereseto Anna
Expression of Nef from unintegrated HIV-1 DNA downregulates cell surface CXCR4 and CCR5 on T-lymphocytes

Author(s): Sloan Richard | Donahue Daniel | Kuhl Björn | Bar-Magen Tamara | Wainberg Mark
Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice

Author(s): Donatella R. M. Negri | Zuleika Michelini | Silvia Baroncelli | Massimo Spada | Silvia Vendetti | Roberta Bona | Pasqualina Leone | Mary E. Klotman | Andrea Cara
Anticipating and blocking HIV-1 escape by second generation antiviral shRNAs

Author(s): Schopman Nick | ter Brake Olivier | Berkhout Ben
Design, Synthesis and Structure-activity Studies of Rhodanine Derivatives as HIV-1 Integrase Inhibitors

Author(s): Kavya Ramkumar | Vladimir N. Yarovenko | Alexandra S. Nikitina | Igor V. Zavarzin | Mikhail M. Krayushkin | Leonid V. Kovalenko | Adrian Esqueda | Srinivas Odde | Nouri Neamati
Characterization of Anti-HIV Activity Mediated by HIV-1 Integrase C-terminal Domain Polypeptides Expressed in Susceptible Cells

Author(s): Zhujun Ao | Kallesh Danappa Jayappa | Meaghan Labine | Yingfeng Zheng | Chris Matthews | Gary Kobinger | Xiaojian Yao
Subtype-associated differences in HIV-1 reverse transcription affect the viral replication

Author(s): Iordanskiy Sergey | Waltke Mackenzie | Feng Yanjun | Wood Charles
Bioactive Dehydrotyrosyl and Dehydrodopyl Compounds of Marine Origin

Author(s): Manickam Sugumaran | William E. Robinson
Role of tipranavir in treatment of patients with multidrug-resistant HIV

Author(s): Joshua D Courter | Colleen J Teevan | Michael H Li | et al
Role of darunavir in the management of HIV infection

Author(s): R Monica Lascar | Paul Benn
Interplay between HIV Entry and Transportin-SR2 Dependency

Author(s): Thys Wannes | De Houwer Stéphanie | Demeulemeester Jonas | Taltynov Oliver | Vancraenenbroeck Renée | Gérard Melanie | De Rijck Jan | Gijsbers Rik | Christ Frauke | Debyser Zeger
Two distinct variants of simian foamy virus in naturally infected mandrills (Mandrillus sphinx) and cross-species transmission to humans

Author(s): Mouinga-Ondémé Augustin | Betsem Edouard | Caron Mélanie | Makuwa Maria | Sallé Bettina | Renault Noemie | Saib Ali | Telfer Paul | Marx Preston | Gessain Antoine | Kazanji Mirdad
Polymorphisms of HIV-2 integrase and selection of resistance to raltegravir

Author(s): Bercoff Danielle | Triqueneaux Perrine | Lambert Christine | Oumar Aboubacar | Ternes Anne-Marie | Dao Sounkalo | Goubau Patrick | Schmit Jean-Claude | Ruelle Jean
HIV integrase variability and genetic barrier in antiretroviral naïve and experienced patients

Author(s): Piralla Antonio | Paolucci Stefania | Gulminetti Roberto | Comolli Giuditta | Baldanti Fausto
Drogas anti-VIH: passado, presente e perspectivas futuras

Author(s): Souza Marcus Vinícius Nora de | Almeida Mauro Vieira de
CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects

Author(s): Rodriguez William | Addo Marylyn | Rathod Almas | Fitzpatrick Cecily | Yu Xu | Perkins Beth | Rosenberg Eric | Altfeld Marcus | Walker Bruce
Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody*

Author(s): Ramcharan Joseph | Colleluori Diana | Merkel George | Andrake Mark | Skalka Anna
HIV-1 replication in cell lines harboring INI1/hSNF5 mutations

Author(s): Sorin Masha | Yung Eric | Wu Xuhong | Kalpana Ganjam
HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein

Author(s): Cianfriglia Maurizio | Dupuis Maria | Molinari Agnese | Verdoliva Antonio | Costi Roberta | Galluzzo Clementina | Andreotti Mauro | Cara Andrea | Di Santo Roberto | Palmisano Lucia
Human Polycomb group EED protein negatively affects HIV-1 assembly and release

Author(s): Rakotobe Dina | Tardy Jean-Claude | André Patrice | Hong Saw | Darlix Jean-Luc | Boulanger Pierre
Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC)

Author(s): Chen Jianping | Hong Kunxue | Jia Mingming | Liu Hongwei | Zhang Yuanzhi | Liu Sha | Zhang Xiaoqing | Zhao Hongjing | Peng Hong | Ma Pengfei | Xing Hui | Ruan Yuhua | Williams Katie | Yu Xu | Altfeld Marcus | Walker Bruce | Shao Yiming
Unintegrated HIV-1 provides an inducible and functional reservoir in untreated and highly active antiretroviral therapy-treated patients

Author(s): Petitjean Gaël | Al Tabaa Yassine | Tuaillon Edouard | Mettling Clement | Baillat Vincent | Reynes Jacques | Segondy Michel | Vendrell Jean
Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors

Author(s): I. Kostova | S. Raleva | P. Genova | R. Argirova
Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication in vitro and provide a rationale to redesign antiretroviral treatment for feline AIDS

Author(s): Savarino Andrea | Pistello Mauro | D'Ostilio Daniela | Zabogli Elisa | Taglia Fabiana | Mancini Fabiola | Ferro Stefania | Matteucci Donatella | De Luca Laura | Barreca Maria | Ciervo Alessandra | Chimirri Alba | Ciccozzi Massimo | Bendinelli Mauro
Design of a trans protease lentiviral packaging system that produces high titer virus

Author(s): Westerman Karen | Ao Zhujun | Cohen Éric | Leboulch Philippe
A quantum-chemical model of the inhibition mechanismof viral DNA HIV-1 replication by Iodine complexcompounds

Author(s): Gulnara A. Yuldasheva | Georgii M. Zhidomirov | Aleksandr I. Ilin
G140S/Q148R and N155H mutations render HIV-2 Integrase resistant to Raltegravir whereas Y143C does not

Author(s): Ni Xiao-Ju | Delelis Olivier | Charpentier Charlotte | Storto Alexandre | Collin Gilles | Damond Florence | Descamps Diane | Mouscadet Jean-François
HIV-1 integrase SUMOylation and viral replication

Author(s): Zamborlini Alessia | Coiffic Audrey | Beauclair Guillaume | Delelis Olivier | Paris Joris | Magne Fabien | Koh Yashuiro | Giron Marie-Lou | Tobaly-Tapiero Joelle | Emiliani Stephane | Engelman Alan | de The Hugues | Saib Ali
PIAS3 modulate HIV-1 integrase SUMOylation

Author(s): Beauclair Guillaume | Paris Joris | Magne Fabien | Zamborlini Alessia | Saϊb Ali
Prediction of the interaction of HIV-I Integrase and Raltegravir through molecular modeling approach

Author(s): Marudamuthu Balakrishnan1*, Thangaraj Sindhu2, Sundarraj Rajamanikandan2
Microwave Assisted Organic Synthesis (MAOS) of Small Molecules as Potential HIV-1 Integrase Inhibitors

Author(s): Stefania Ferro | Sara De Grazia | Laura De Luca | Rosaria Gitto | Caterina Elisa Faliti | Zeger Debyzer | Alba Chimirri
HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin

Author(s): Astiazaran Paulina | Bueno Murilo | Morales Elisa | Kugelman Jeffrey | Garcia-Rivera Jose | Llano Manuel
Optimizing HIV-1 protease production in Escherichia coli as fusion protein

Author(s): Volontè Federica | Piubelli Luciano | Pollegioni Loredano
The role of unintegrated DNA in HIV infection

Author(s): Sloan Richard | Wainberg Mark
Characterization of HIV-1 Genotypes and Antiretroviral Drug-resistance Mutations among Patients in Burkina Faso

Author(s): T.S. Kagone | H. Hien | N. Meda | P.S. Diagbouga | A. Sawadogo | J. Drabo | M. Peeters | L. Vergne | E. Delaporte | C. De Souza | M. Gbeassor | J. Simpore
Integrase Strand Transfer Inhibitors as potential anti-HIV agent

Author(s): Sabina Yasmin, Karampuri Srinivas, Ashoke Sharon and Chandralata Bal
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