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Up-regulation of HLA class I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating hydralazine and the histone deacetylase inhibitor valproic acid

Author(s): Mora-García María | Duenas-González Alfonso | Hernández-Montes Jorge | Weiss-Steider Benny | Santiago-Osorio Edelmiro | Ortíz-Navarrete Vianney | Rosales Víctor | Cantú David | Lizano-Soberón Marcela | Monroy-García Alberto
Vorinostat in solid and hematologic malignancies

Author(s): Siegel David | Hussein Mohamad | Belani Chandra | Robert Francisco | Galanis Evanthia | Richon Victoria | Garcia-Vargas José | Sanz-Rodriguez Cesar | Rizvi Syed
HDAC inhibitors stimulate viral transcription by multiple mechanisms

Author(s): Balakrishnan Lata | Milavetz Barry
Butyrate stimulates IL-32α expression in human intestinal epithelial cell lines

Author(s): Ayako Kobori, Shigeki Bamba, Hirotsugu Imaeda, Hiromitsu Ban, Tomoyuki Tsujikawa, Yasuharu Saito, Yoshihide Fujiyama, Akira Andoh
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer

Author(s): Tadateru Maehata, Hiroaki Taniguchi, Hiroyuki Yamamoto, Katsuhiko Nosho, Yasushi Adachi, Nobuki Miyamoto, Chie Miyamoto, Noriyuki Akutsu, Satoshi Yamaoka, Fumio Itoh
Histone deacetylase inhibitors: A new mode for inhibition of cholesterol metabolism

Author(s): Chittur Sridar | Sangster-Guity Niquiche | McCormick Paulette
Trichostatin A treatment of cloned mouse embryos improves constitutive heterochromatin remodeling as well as developmental potential to term

Author(s): Maalouf Walid | Liu Zichuan | Brochard Vincent | Renard Jean-Paul | Debey Pascale | Beaujean Nathalie | Zink Daniele
Histone Deacetylase-Inhibitors Sensitize Human Prostate Cancer Cell Lines to Growth Suppression and Apoptosis by Retinoids

Author(s): Jian Gu | Xianshi Zhao | Remco A. Spanjaard | Tai C. Chen | John N. Flanagan | Michael Boosalis | Susan P. Perrine | Douglas V. Faller
"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence

Author(s): Savarino Andrea | Mai Antonello | Norelli Sandro | El Daker Sary | Valente Sergio | Rotili Dante | Altucci Lucia | Palamara Anna | Garaci Enrico
The 14-3-3σ gene promoter is methylated in both human melanocytes and melanoma

Author(s): Liu Suhu | Howell Paul | Ren Suping | Fodstad Oystein | Riker Adam
HIPK2 modulates p53 activity towards pro-apoptotic transcription

Author(s): Puca Rosa | Nardinocchi Lavinia | Sacchi Ada | Rechavi Gideon | Givol David | D'Orazi Gabriella
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action

Author(s): Wang Shan | Liu Qian | Zhang Ying | Liu Ke | Yu Pengfei | Liu Kun | Luan Jinling | Duan Huiying | Lu Zhaoqiao | Wang Fengfei | Wu Erxi | Yagasaki Kazumi | Zhang Guoying
Histone Deacetylase Inhibitor Therapy in Epithelial Ovarian Cancer

Author(s): Noriyuki Takai | Hisashi Narahara
PCI-24781, a Novel Hydroxamic Acid HDAC Inhibitor, Exerts Cytotoxicity and Histone Alterations via Caspase-8 and FADD in Leukemia Cells

Author(s): Nilsa Rivera-Del Valle | Shan Gao | Claudia P. Miller | Joy Fulbright | Carolina Gonzales | Mint Sirisawad | Susanne Steggerda | Jennifer Wheler | Sriram Balasubramanian | Joya Chandra
Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils

Author(s): Kankaanranta Hannu | Janka-Junttila Mirkka | Ilmarinen-Salo Pinja | Ito Kazuhiro | Jalonen Ulla | Ito Misako | Adcock Ian | Moilanen Eeva | Zhang Xianzhi
Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation

Author(s): Mercer Tim | Qureshi Irfan | Gokhan Solen | Dinger Marcel | Li Guangyu | Mattick John | Mehler Mark
Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation

Author(s): Wu Yanyuan | Alvarez Monica | Slamon Dennis | Koeffler Phillip | Vadgama Jaydutt
Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice

Author(s): Ni Yun-Feng | Wang Jian | Yan Xiao-Long | Tian Feng | Zhao Jin-Bo | Wang Yun-Jie | Jiang Tao
Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo

Author(s): Hrzenjak Andelko | Moinfar Farid | Kremser Marie-Luise | Strohmeier Bettina | Petru Edgar | Zatloukal Kurt | Denk Helmut
Effective transgene constructs for combination suicide gene therapy with trichostatin A

Author(s): Yuhua Ma | Tomoko Kohno | Masayuki Igarashi | Kiyoshi Yasui | Koon Jiew Chua | Toshifumi Matsuyama | Hideki Hayashi
The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

Author(s): Lee Jaehyouk | Jeong Dong-Jun | Kim Jinsun | Lee Soonduck | Park Jin-Hwa | Chang Boogi | Jung Sam-Il | Yi Lisha | Han Youngsoo | Yang Young | Kim Keun | Lim Jong-Seok | Yang Inchul | Jeon Seob | Bae Dong | Kim Chang-Jin | Lee Myeong-Sok
Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice

Author(s): Marshall Henderson | Bhaumik Mantu | Aviv Hana | Moore Dirk | Yao Ming | Dutta Jayeeta | Rahim Hussein | Gounder Murugesan | Ganesan Shridar | Saleem Ahamed | Rubin Eric
Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line

Author(s): Waby Jennifer | Chirakkal Haridasan | Yu ChenWei | Griffiths Gareth | Benson Roderick | Bingle Colin | Corfe Bernard
Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression

Author(s): Ganesan Shyamala | Faris Andrea | Comstock Adam | Chattoraj Sangbrita | Chattoraj Asamanja | Burgess John | Curtis Jeffrey | Martinez Fernando | Zick Suzanna | Hershenson Marc | Sajjan Uma
Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation

Author(s): Yu Danny | Waby Jennifer | Chirakkal Haridasan | Staton Carolyn | Corfe Bernard
Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance

Author(s): Jennifer S Carew | Steffan T Nawrocki | Francis J Giles | John L Cleveland
Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma

Author(s): Carén Helena | Djos Anna | Nethander Maria | Sjöberg Rose-Marie | Kogner Per | Enström Camilla | Nilsson Staffan | Martinsson Tommy
Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd+2 or As+3 transformed human urothelial cells

Author(s): Somji Seema | Garrett Scott | Toni Conrad | Zhou Xu | Zheng Yun | Ajjimaporn Amornpan | Sens Mary | Sens Donald
ER stress response plays an important role in aggregation of α-synuclein

Author(s): Jiang Peizhou | Gan Ming | Ebrahim Abdul | Lin Wen-Lang | Melrose Heather | Yen Shu-Hui
Direct hepatic differentiation of mouse embryonic stem cells induced by valproic acid and cytokines

Author(s): Xue-Jun Dong, Guo-Rong Zhang, Qing-Jun Zhou, Ruo-Lang Pan, Ye Chen, Li-Xin Xiang, Jian-Zhong Shao
Experimental treatment of pancreatic cancer with two novel histone deacetylase inhibitors

Author(s): Martin Haefner, Thilo Bluethner, Manuel Niederhagen, Christian Moebius, Christian Wittekind, Joachim Mossner, Karel Caca, Marcus Wiedmann
Evaluation of muscle strength and motor abilities in children with type II and III spinal muscle atrophy treated with valproic acid

Author(s): Darbar Illora | Plaggert Paulo | Resende Maria Bernadete | Zanoteli Edmar | Reed Umbertina
QSAR Study of Novel Benzothiophene Derivatives as Potent Anticancer Agent

Author(s): Satish K. Sarankar | Kalpna Tomar | Jitendra Bajaj | Parul Mehta | A.K. Pathak | Mukul Tailang
The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses

Author(s): Moreira José | Scheipers Peter | Sørensen Poul
Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study

Author(s): Chavez-Blanco Alma | Segura-Pacheco Blanca | Perez-Cardenas Enrique | Taja-Chayeb Lucia | Cetina Lucely | Candelaria Myrna | Cantu David | Gonzalez-Fierro Aurora | Garcia-Lopez Patricia | Zambrano Pilar | Perez-Plasencia Carlos | Cabrera Gustavo | Trejo-Becerril Catalina | Angeles Enrique | Duenas-Gonzalez Alfonso
Transformation of human bronchial epithelial cells alters responsiveness to inflammatory cytokines

Author(s): Loewen Gregory | Tracy Erin | Blanchard Frédéric | Tan Dongfeng | Yu Jihnhee | Raza Sameera | Matsui Sei-Ichi | Baumann Heinz
Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency

Author(s): Munier Sandie | Delcroix-Genête Delphine | Carthagéna Laëtitia | Gumez Audrey | Hazan Uriel
Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast.

Author(s): Kaeberlein | Hu | Kerr | Tsuchiya | Westman | Dang | Fields | Kennedy
Histone deacetylase inhibitor, Trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells

Author(s): Alao John | Stavropoulou Alexandra | Lam Eric | Charles Coombes R | Vigushin David
Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines

Author(s): Chavez-Blanco Alma | Perez-Plasencia Carlos | Perez-Cardenas Enrique | Carrasco-Legleu Claudia | Rangel-Lopez Edgar | Segura-Pacheco Blanca | Taja-Chayeb Lucia | Trejo-Becerril Catalina | Gonzalez-Fierro Aurora | Candelaria Myrna | Cabrera Gustavo | Duenas-Gonzalez Alfonso
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers

Author(s): Paulsen Michelle | Starks Adrienne | Derheimer Frederick | Hanasoge Sheela | Li Liwu | Dixon Jack | Ljungman Mats
Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition

Author(s): Flatmark Kjersti | Nome Ragnhild | Folkvord Sigurd | Bratland Åse | Rasmussen Heidi | Ellefsen Mali | Fodstad Øystein | Ree Anne
Methylation mediated silencing of TMS1/ASC gene in prostate cancer

Author(s): Das Partha | Ramachandran Kavitha | VanWert Jane | Ferdinand Larry | Gopisetty Gopal | Reis Isildinha | Singal Rakesh
Comparative evaluation of the treatment efficacy of suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer cell lines and primary ovarian cancer cells from patients

Author(s): Sonnemann Jürgen | Gänge Jennifer | Pilz Sabine | Stötzer Christine | Ohlinger Ralf | Belau Antje | Lorenz Gerd | Beck James
Combination phenylbutyrate/gemcitabine therapy effectively inhibits in vitro and in vivo growth of NSCLC by intrinsic apoptotic pathways

Author(s): Schniewind Bodo | Heintz Kirsten | Kurdow Roland | Ammerpohl Ole | Trauzold Anna | Emme Doris | Dohrmann Peter | Kalthoff Holger
Up-regulation of HLA class-I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating agent hydralazine and the histone deacetylase inhibitor valproic acid

Author(s): Mora-García María | Duenas-González Alfonso | Hernández-Montes Jorge | De la Cruz-Hernández Erick | Pérez-Cárdenas Enrique | Weiss-Steider Benny | Santiago-Osorio Edelmiro | Ortíz-Navarrete Vianney | Rosales Víctor | Cantú David | Lizano-Soberón Marcela | Rojo-Aguilar Martha | Monroy-García Alberto
The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo

Author(s): Buckley Michael | Yoon Joanne | Yee Herman | Chiriboga Luis | Liebes Leonard | Ara Gulshan | Qian Xiaozhong | Bajorin Dean | Sun Tung-Tien | Wu Xue-Ru | Osman Iman
HDAC inhibitor valproic acid upregulates CAR in vitro and in vivo

Author(s): Segura-Pacheco Blanca | Avalos Berenice | Rangel Edgar | Velazquez Dora | Cabrera Gustavo
Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways

Author(s): Lu Quanyi | Lin Xianghua | Feng Jean | Zhao Xiangmin | Gallagher Ruth | Lee Marietta | Chiao Jen-Wei | Liu Delong
Epigenetic Regulation of EpCAM in Tumor Invasion and Metastasis

Author(s): Shine-Gwo Shiah | Kang-Yu Tai | Cheng-Wen Wu
Growth inhibitory effect of 4-phenyl butyric acid on human gastric cancer cells is associated with cell cycle arrest

Author(s): Long-Zhu Li | Hong-Xia Deng | Wen-Zhu Lou | Xue-Yan Sun | Meng-Wan Song | Jing Tao | Bing-Xiu Xiao | Jun-Ming Guo
Dynamic Structure-Based Pharmacophore Model Development: A New and Effective Addition in the Histone Deacetylase 8 (HDAC8) Inhibitor Discovery

Author(s): Sundarapandian Thangapandian | Shalini John | Yuno Lee | Songmi Kim | Keun Woo Lee
Improved Histone Deacetylase Inhibitors as Therapeutics for the Neurodegenerative Disease Friedreich’s Ataxia: A New Synthetic Route

Author(s): Chunping Xu | Elisabetta Soragni | Vincent Jacques | James R. Rusche | Joel M. Gottesfeld
Genetic Function Approximation and Bayesian Models for the Discovery of Future HDAC8 Inhibitors

Author(s): Sundarapandian Thangapandian | Shalini John | Keun Woo Lee
Novel histone deacetylase inhibitor exhibits antitumor activity via apoptosis induction in oral squamous cell carcinoma

Author(s): Osamu Takahashi | Toshinori Okinaga | Kenjiro Iwanaga | Manabu Habu | Wataru Ariyoshi | Kazuhiro Tominaga | Norikazu Nishino | Tatsuji Nishihara
Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis

Author(s): Wedel Steffen | Hudak Lukasz | Seibel Jens-Michael | Makarević Jasmina | Juengel Eva | Tsaur Igor | Waaga-Gasser Ana | Haferkamp Axel | Blaheta Roman
Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90

Author(s): Zhao Ming | Ma Jian | Zhu Hai-Yan | Zhang Xu-Hui | Du Zhi-Yan | Xu Yuan-Ji | Yu Xiao-Dan
Epigenetic modulation with oral histone deacetylase (HDAC) inhibitor as a new treatment option in JIA

Author(s): Vojinovic J | Furlan A | Damjanov N | D’Urzo C | Dinarello CA
The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells

Author(s): Weberpals Johanne | O'Brien Anna | Niknejad Nima | Garbuio Kyla | Clark-Knowles Katherine | Dimitroulakos Jim
Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines

Author(s): Oertel Susanne | Thiemann Markus | Richter Karsten | Weber Klaus-J | Huber Peter | Perez Ramon | Brons Stephan | Bischof Marc | Kulozik Andreas | Ehemann Volker | Debus Jürgen | Blattmann Claudia
NBM-HD-1: A Novel Histone Deacetylase Inhibitor with Anticancer Activity

Author(s): Wei-Jan Huang | Yu-Chih Liang | Shuang-En Chuang | Li-Ling Chi | Chi-Yun Lee | Chia-Wei Lin | Ai-Ling Chen | Jing-Shi Huang | Chun-Jung Chiu | Cheng-Feng Lee | Chung-Yang Huang | Chia-Nan Chen
Combined inhibitors of angiogenesis and histone deacetylase: Efficacy in rat hepatoma

Author(s): Marion Ganslmayer | Annette Zimmermann | Steffen Zopf | Christoph Herold
A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression

Author(s): Ni ZhenHua | Tang JiHong | Cai ZhuYing | Yang Wei | Zhang Lei | Chen Qingge | Zhang Long | Wang XiongBiao
SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation

Author(s): Acun Tolga | Oztas Emin | Yagci Tamer | Yakicier Mustafa
The metabolic advantage of tumor cells

Author(s): Israël Maurice | Schwartz Laurent
Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly

Author(s): Rajendran Praveen | Delage Barbara | Dashwood W Mohaiza | Yu Tian-Wei | Wuth Bradyn | Williams David | Ho Emily | Dashwood Roderick
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