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Search Articles for "excitotoxicity; demyelinating diseases"

Human Neuroepithelial Cells Express NMDA Receptors

Author(s): Sharp Christopher | Fowler M | Jackson TH | Houghton J | Warren A | Nanda A | Chandler I | Cappell B | Long A | Minagar A | Alexander JS
Chronic NMDA administration to rats increases brain pro-apoptotic factors while decreasing anti-Apoptotic factors and causes cell death

Author(s): Kim Hyung-Wook | Chang Yunyoung | Chen Mei | Rapoport Stanley | Rao Jagadeesh
Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor

Author(s): Carlson Noel | Rojas Monica | Black John-David | Redd Jonathan | Hille John | Hill Kenneth | Rose John
Excitotoxicity and the putative involvement of excitative amino acids in neurodegenerative diseases

Author(s): Andre Nieoullon | Laurence Had-Aissouni | Lydia Kerkerian-le Goff
Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis

Author(s): Tovar-y-Romo Luis | Santa-Cruz Luz | Tapia Ricardo
Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

Author(s): Faust Katharina | Gehrke Stephan | Yang Yufeng | Yang Lichuan | Beal M Flint | Lu Bingwei
Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release

Author(s): Seong‑Woon Yu | Yingfei Wang | Didrik S Frydenlund | Ole Petter Ottersen | Valina L Dawson | Ted M Dawson
Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype

Author(s): Sadasivan Shankar | Zhang Zhiqun | Larner Stephen | Liu Ming | Zheng Wenrong | Kobeissy Firas | Hayes Ronald | Wang Kevin
Kainic acid-induced microglial activation is attenuated in aged interleukin-18 deficient mice

Author(s): Zhang Xing-Mei | Jin Tao | Quezada Hernan | Mix Eilhard | Winblad Bengt | Zhu Jie

Author(s): M. Swamy, Mohd Jamsani Mat Salleh, K. N .S. Sirajudeen, Wan Roslina Wan Yusof, G. Chandran
Effect of glutamate antagonists on nitric oxide production in rat brain following intrahippocampal injection

Author(s): Radenović Lidija | Selaković Vesna | Janać Branka | Todorović Dajana
Nerve growth factor protects cholinergic neurons against quinolinic acid-induced excitotoxicity in wistar rats

Author(s): Vasiljević Ivana D. | Jovanović Marina D. | Čolić Miodrag J. | Mićić D. | Ninković Milica | Maličević Živorad
Spatio-temporal expression of a novel neuron-derived neurotrophic factor (NDNF) in mouse brains during development

Author(s): Kuang Xiu-Li | Zhao Xiao-Mei | Xu Hai-Fang | Shi Yuan-Yuan | Deng Jin-Bo | Sun Guo-Tao
Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models

Author(s): Yang Eun Jin | Jiang Jing Hua | Lee Sang Min | Yang Sun Choel | Hwang Hye Suk | Lee Myeong Soo | Choi Sun-Mi
Glutamate pathway implication in amyotrophic lateral sclerosis: what is the signal in the noise?

Author(s): Virginia Le Verche | Burcin Ikiz | Arnaud Jacquier | et al
Role of plasma membrane calcium ATPase 2 in spinal cord pathology

Author(s): Amanda Kathleen Fakira | Stella Elkabes
Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway

Author(s): Guo Huang | Barrett Theresa | Zhong Zhihui | Fernández José | Griffin John | Freeman Robert | Zlokovic Berislav
PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

Author(s): Chaitanya Ganta | Alexander Jonathan | Babu Phanithi
Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum

Author(s): Kevin N Hascup | Xiaodong Bao | Erin R Hascup | Dongwei Hui | Wenhao Xu | Francois Pomerleau | Peter Huettl | Mary L Michaelis | Elias K Michaelis | Greg A Gerhardt
Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies

Author(s): Rojas Camilo | Stathis Marigo | Polydefkis Michael | Rudek Michelle | Zhao Ming | Ebenezer Gigi | Slusher Barbara
Induction of serine racemase expression and D-serine release from microglia by amyloid β-peptide

Author(s): Wu Sheng-Zhou | Bodles Angela | Porter Mandy | Griffin W Sue | Basile Anthony | Barger Steven
Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders

Author(s): Lynex Clare | Carr Ian | Leek Jack | Achuthan Rajgopal | Mitchell Simon | Maher Eamonn | Woods C Geoffrey | Bonthon David | Markham Alex
Proliferation dynamics of germinative zone cells in the intact and excitotoxically lesioned postnatal rat brain

Author(s): Faiz Maryam | Acarin Laia | Castellano Bernardo | Gonzalez Berta
Susceptibility to neurodegeneration in a glaucoma is modified by bax gene dosage.

Author(s): Libby Richard T | Li Yan | Savinova Olga V | Barter Joseph | Smith Richard S | Nickells Robert W | John Simon W M
Role of Nitric Oxide in Domoic Acid Induced Hippocampal Degeneration

Author(s): Manju PANDE | Avery HARPS | Mecheri SUNDARAM | Parminder JS VIG
Sub region-specific modulation of synchronous neuronal burst firing after a kainic acid insult in organotypic hippocampal cultures

Author(s): Reid Christopher | Adams Brendan | Myers Damian | O'Brien Terence | Williams David
Non-cell autonomous influence of the astrocyte system xc− on hypoglycaemic neuronal cell death

Author(s): Nicole A Jackman | Shannon E Melchior | James A Hewett | Sandra J Hewett
Chronic excitotoxin-induced axon degeneration in a compartmented neuronal culture model

Author(s): Katherine A Hosie | Anna E King | Catherine A Blizzard | James C Vickers | Tracey C Dickson
Quinolinic Acid, an Endogenous Molecule Combining Excitotoxicity, Oxidative Stress and Other Toxic Mechanisms

Author(s): Verónica Pérez-De La Cruz | Paul Carrillo-Mora | Abel Santamaría
Ginseng Use in Medicine: Perspectives on CNS Disorders

Author(s): Khaled Radad | Gabriele Gille | Wolf-Dieter Rausch
Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats

Author(s): Lai Pei | Huang Yen | Wu Chia | Lai Ching-Jung | Wang Pen | Chiu Ted
Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo

Author(s): Jullienne Amandine | Montagne Axel | Orset Cyrille | Lesept Flavie | Jane David | Monaghan Daniel | Maubert Eric | Vivien Denis | Ali Carine
Electro-acupuncture could be an effective pretreatment for cerebral ischemia

Author(s): Feng Zhang | Yi Wu | Jie Jia | Qing-Chuan Guo | Yong-Shan Hu
Does α-Amino-β-methylaminopropionic Acid (BMAA) Play a Role in Neurodegeneration?

Author(s): Alexander S. Chiu | Michelle M. Gehringer | Jeffrey H. Welch | Brett A. Neilan
Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons

Author(s): Ahn Seo-Hee | Kim Hee | Jeong Imju | Hong Yi | Kim Myung-Jun | Rhie Duck-Joo | Jo Yang-Hyeok | Hahn Sang | Yoon Shin
MK801 attenuates secondary injury in a mouse experimental compression model of spinal cord trauma

Author(s): Esposito Emanuela | Paterniti Irene | Mazzon Emanuela | Genovese Tiziana | Galuppo Maria | Meli Rosaria | Bramanti Placido | Cuzzocrea Salvatore
Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects

Author(s): Paterniti Irene | Melani Alessia | Cipriani Sara | Corti Francesca | Mello Tommaso | Mazzon Emanuela | Esposito Emanuela | Bramanti Placido | Cuzzocrea Salvatore | Pedata Felicita
Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke

Author(s): Rodríguez-González Raquel | Sobrino Tomás | Rodríguez-Yáñez Manuel | Millán Mónica | Brea David | Miranda Elena | Moldes Octavio | Pérez Juan | Lomas David | Leira Rogelio | Dávalos Antoni | Castillo José
Increased expression of cystine/glutamate antiporter in multiple sclerosis

Author(s): Pampliega Olatz | Domercq María | Soria Federico | Villoslada Pablo | Rodríguez-Antigüedad Alfredo | Matute Carlos
Melittin restores proteasome function in an animal model of ALS

Author(s): Yang Eun Jin | Kim Seon Hwy | Yang Sun Choel | Lee Sang Min | Choi Sun-Mi
The Effect of Yaji-Meat-Sauce Consumption on Cerebellar Neurons of White Albino Rats

Author(s): A.O. Nwaopara | U. Akpamu | A.M. Izunya | G.A. Oaikhena | O. Okhiai | L.C. Anyanwu | B.O. Idonije | G.P. Oyadonghon
Neuroprotective Effects of Sodium Ferulate and Its Antidepressant-Like Effect Measured by Acute and Chronic Experimental Methods in Animal Models of Depression

Author(s): Yongping Zhang | Lijian Yu | Yanping Wang | Mingneng Liao | Xia Zhang | Rundi Ma | Xiaoyu Zhang | Tingxi Yu
Pre-conditioning induces the precocious differentiation of neonatal astrocytes to enhance their neuroprotective properties

Author(s): Ellora Sen | Anirban Basu | Lisa B Willing | Tracy F Uliasz | Jaimie L Myrkalo | Susan J Vannucci | Sandra J Hewett | Steven W Levison
The role of intracellular sodium (Na+) in the regulation of calcium (Ca2+)-mediated signaling and toxicity

Author(s): Xian-Min Yu | Bradley R. Groveman | Xiao-Qian Fang | Shuang-Xiu Lin
Advances in Oligoprotection

Author(s): Hong Liao | Dixit Sanjaya Mani
A Nucleotide-based Drug Protects Against Glutamate- and MPP+- Induced Neurotoxicity

Author(s): Alejandro Gella | Tania Martiañez | Aloa Lamarca | Cristina Gutierrez
Forebrain striatal-specific expression of mutant huntingtin protein in vivo induces cell-autonomous age-dependent alterations in sensitivity to excitotoxicity and mitochondrial function

Author(s): Soong Ho Kim | Carlos A Thomas | Véronique M André | Damian M Cummings | Carlos Cepeda | Michael S Levine | Michelle E Ehrlich
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