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Search Articles for "mTOR inhibitors"

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Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy

Author(s): Yuan RuiRong | Kay Andrea | Berg William | Lebwohl David
Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model

Author(s): Rauktys Aubrey | Lee Nancy | Lee Laifong | Dabora Sandra
Management of metastatic renal cell carcinoma in patients with poor prognosis

Author(s): Andrea Bullock | David F McDermott | Michael B Atkins
Everolimus – a new approach in the treatment of renal cell carcinoma

Author(s): G Anandappa | AE Hollingdale | TG Eisen
Targeted therapy in lymphoma

Author(s): Johnston Patrick | Yuan RuiRong | Cavalli Franco | Witzig Thomas
A Decade of Experience Using mTor Inhibitors in Liver Transplantation

Author(s): Jeffrey Campsen | Michael A. Zimmerman | Susan Mandell | Maria Kaplan | Igal Kam
Diurnal variation of the human adipose transcriptome and the link to metabolic disease

Author(s): Loboda Andrey | Kraft Walter | Fine Bernard | Joseph Jeffrey | Nebozhyn Michael | Zhang Chunsheng | He Yudong | Yang Xia | Wright Christopher | Morris Mark | Chalikonda Ira | Ferguson Mark | Emilsson Valur | Leonardson Amy | Lamb John | Dai Hongyue | Schadt Eric | Greenberg Howard | Lum Pek
Temsirolimus: a review of its use in the treatment of advanced renal cell carcinoma

Author(s): Fanny Chan | Erika E. Samlowski | Wolfram E. Samlowski
The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events

Author(s): Bhaskar Kiran | Miller Megan | Chludzinski Alexandra | Herrup Karl | Zagorski Michael | Lamb Bruce
Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells

Author(s): Juengel Eva | Engler Johanna | Natsheh Iyad | Jones Jon | Mickuckyte Ausra | Hudak Lukasz | Jonas Dietger | Blaheta Roman
ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside

Author(s): Zhou Jianbiao | Goh Boon-Cher | Albert Daniel | Chen Chien-Shing
Chemotherapy in adult soft tissue sarcoma

Author(s): Jain A | Sajeevan K | Babu K | Lakshmaiah K
A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy

Author(s): Nakamura Yoshitaka | Yogosawa Shingo | Izutani Yasuyuki | Watanabe Hirotsuna | Otsuji Eigo | Sakai Tosiyuki
Methylnaltrexone Potentiates the Anti-Angiogenic Effects of mTOR Inhibitors

Author(s): Singleton Patrick | Mambetsariev Nurbek | Lennon Frances | Mathew Biji | Siegler Jessica | Moreno-Vinasco Liliana | Salgia Ravi | Moss Jonathan | Garcia Joe
F-Prostaglandin receptor regulates endothelial cell function via fibroblast growth factor-2

Author(s): Keightley Margaret | Brown Pamela | Jabbour Henry | Sales Kurt
A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma

Author(s): Schnitzbauer Andreas | Zuelke Carl | Graeb Christian | Rochon Justine | Bilbao Itxarone | Burra Patrizia | de Jong Koert | Duvoux Christophe | Kneteman Norman | Adam Rene | Bechstein Wolf | Becker Thomas | Beckebaum Susanne | Chazouillères Olivier | Cillo Umberto | Colledan Michele | Fändrich Fred | Gugenheim Jean | Hauss Johann | Heise Michael | Hidalgo Ernest | Jamieson Neville | Königsrainer Alfred | Lamby Philipp | Lerut Jan | Mäkisalo Heikki | Margreiter Raimund | Mazzaferro Vincenzo | Mutzbauer Ingrid | Otto Gerd | Pageaux Georges-Philippe | Pinna Antonio | Pirenne Jacques | Rizell Magnus | Rossi Giorgio | Rostaing Lionel | Roy Andre | Turrion Victor | Schmidt Jan | Troisi Roberto | van Hoek Bart | Valente Umberto | Wolf Philippe | Wolters Heiner | Mirza Darius | Scholz Tim | Steininger Rudolf | Soderdahl Gunnar | Strasser Simone | Jauch Karl-Walter | Neuhaus Peter | Schlitt Hans | Geissler Edward
Systemic treatment of chronic GVHD

Author(s): Michael Schleuning
Therapy of acute graft-versus-host disease

Author(s): Malte von Bonin | Martin Wermke | Uwe Platzbecker | Jörgen Radke | Nona Shayegi | Susanne Gretzinger | Konrad Heuchel | Kristina Hölig | Marc Schmitz | Gerhard Ehninger | Johannes Schetelig | Martin Bornhäuser
Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies

Author(s): Javle Milind | Shroff Rachna | Xiong Henry | Varadhachary Gauri | Fogelman David | Reddy Shrikanth | Davis Darren | Zhang Yujian | Wolff Robert | Abbruzzese James
Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition

Author(s): Charette Nicolas | De Saeger Christine | Lannoy Valérie | Horsmans Yves | Leclercq Isabelle | Stärkel Peter
Novel antibodies against RCD-8 as a tool to study processing bodies

Author(s): Gudkova D. O. | Panasyuk G. G. | Nemazanyy I. O. | Filonenko V. V.
Dasatinib in the treatment of imatinib refractory chronic myeloid leukemia

Author(s): Radhakrishnan Ramchandren | Charles A Schiffer
Multiple roles and therapeutic implications of Akt signaling in cancer

Author(s): Emiliano Calvo | Victoria Bolós | Enrique Grande
Impact of everolimus: update on immunosuppressive therapy strategies and patient outcomes after renal transplantation

Author(s): Helio Tedesco-Silva Jr | Claudia Rosso Felipe | Tainá Veras de Sandes Freitas | et al
Staphylococcus aureus α-Toxin Triggers the Synthesis of B-Cell Lymphoma 3 by Human Platelets

Author(s): Sebastian Schubert | Hansjörg Schwertz | Andrew S. Weyrich | Zechariah G. Franks | Stephan Lindemann | Monika Otto | Hagen Behr | Harald Loppnow | Axel Schlitt | Martin Russ | Peter Presek | Karl Werdan | Michael Buerke
Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer

Author(s): Satheesha Sampoorna | Cookson Victoria | Coleman Louise | Ingram Nicola | Madhok Brijesh | Hanby Andrew | Suleman Charlotte | Sabine Vicky | Macaskill E Jane | Bartlett John | Dixon J Michael | McElwaine Jim | Hughes Thomas
BCR-ABL1-independent PI3Kinase activation causing imatinib-resistance

Author(s): Quentmeier Hilmar | Eberth Sonja | Romani Julia | Zaborski Margarete | Drexler Hans
The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes

Author(s): Lisi Lucia | Navarra Pierluigi | Feinstein Douglas | Dello Russo Cinzia
Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET

Author(s): Pantaleo Maria | Nicoletti Giordano | Nanni Cristina | Gnocchi Chiara | Landuzzi Lorena | Quarta Carmelo | Boschi Stefano | Nannini Margherita | Di Battista Monica | Castellucci Paolo | Fanti Stefano | Lollini Pier | Bellan Elena | Castelli Mauro | Rubello Domenico | Biasco Guido
Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis

Author(s): Gu Ling | Zhou Chenyan | Liu Huajun | Gao Ju | Li Qiang | Mu Dezhi | Ma Zhigui
Overview of immunosuppression in liver transplantation

Author(s): Anjana A Pillai, Josh Levitsky
Targeting the Mammalian Target of Rapamycin (mTOR) in Cancer Therapy: Lessons from Past and Future Perspectives

Author(s): Marc Dufour | Anne Dormond-Meuwly | Nicolas Demartines | Olivier Dormond
Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction

Author(s): Schulze-Bergkamen Henning | Fleischer Binje | Schuchmann Marcus | Weber Achim | Weinmann Arndt | Krammer Peter | Galle Peter
FRS2α is Essential for the Fibroblast Growth Factor to Regulate the mTOR Pathway and Autophagy in Mouse Embryonic Fibroblasts

Author(s): Xiang Lin, Yongyou Zhang, Leyuan Liu, Wallace L. McKeehan, Yuemao Shen, Siyang Song, Fen Wang
Medical Treatment of Gastroenteropancreatic Neuroendocrine Tumors

Author(s): Anja Rinke | Patrick Michl | Thomas Gress
The mTOR Signalling Pathway in Human Cancer

Author(s): Helena Pópulo | José Manuel Lopes | Paula Soares
Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer

Author(s): Elfiky Aymen | Aziz Saadia | Conrad Patricia | Siddiqui Summar | Hackl Wolfgang | Maira Michel | Robert Camp | Kluger Harriet
Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways

Author(s): Pickhard Anja | Margraf Johanna | Knopf Andreas | Stark Thomas | Piontek Guido | Beck Carolin | Boulesteix Anne-Laure | Scherer Elias | Pigorsch Steffi | Schlegel Jürgen | Arnold Wolfgang | Reiter Rudolf
Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation

Author(s): Jiao Yisheng | Ou Wenbin | Meng Fanguo | Zhou Haimeng | Wang Aiyuan
PI3K/mTOR-dependent signaling pathway as a possible regulator of processing bodies’ assembly

Author(s): Gudkova D. O. | Panasyuk G. G. | Nemazanyy I. O. | Filonenko V. V.
Role of Radiation Therapy in the Management of Renal Cell Cancer

Author(s): Angel I. Blanco | Bin S. Teh | Robert J. Amato
Intrinsic resistance to tyrosine kinase inhibitors is associated with poor clinical outcome in metastatic renal cell carcinoma

Author(s): Busch Jonas | Seidel Christoph | Weikert Steffen | Wolff Ingmar | Kempkensteffen Carsten | Weinkauf Lisa | Hinz Stefan | Magheli Ahmed | Miller Kurt | Grünwald Viktor
Targeting renal cell carcinoma with NVP-BEZ235, a dual PI3K/mTOR inhibitor, in combination with sorafenib

Author(s): Roulin Didier | Waselle Laurent | Dormond-Meuwly Anne | Dufour Marc | Demartines Nicolas | Dormond Olivier
The Role of mTOR Inhibitors for the Treatment of B-Cell Lymphomas

Author(s): Pinelopi Argyriou | Panagiota Economopoulou | Sotirios Papageorgiou
Everolimus in kidney transplantation

Author(s): Cooper JE | Christians U | Wiseman AC
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