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Dual Specificity Phosphatase 1 Regulates Human Inducible NitricOxide Synthase Expression by p38 MAP Kinase

Author(s): Tuija Turpeinen | Riina Nieminen | Ville Taimi | Taina Heittola | Outi Sareila | Andrew R. Clark | Eeva Moilanen | Riku Korhonen
Topical alpha-selective p38 MAP kinase inhibition reduces acute skin inflammation in guinea pig

Author(s): Satyanarayana Medicherla | Jing Ying Ma | Mamtha Reddy | et al
Physiological roles of mitogen-activated-protein-kinase-activated p38-regulated/activated protein kinase

Author(s): Sergiy Kostenko | Gianina Dumitriu | Kari Jenssen Lægreid | Ugo Moens
Functional blockade of α5β1 integrin induces scattering and genomic landscape remodeling of hepatic progenitor cells

Author(s): Vellón Luciano | Royo Félix | Matthiesen Rune | Torres-Fuenzalida José | Lorenti Alicia | Parada Luis
PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes

Author(s): Rohani Maryam | DiJulio Dennis | An Jonathan | Hacker Beth | Dale Beverly | Chung Whasun
Reactive oxygen species: A double-edged sword in oncogenesis

Author(s): Jin-Shui Pan, Mei-Zhu Hong, Jian-Lin Ren
Schwann Cell Migration Induced by Earthworm Extract via Activation of PAs and MMP2/9 Mediated through ERK1/2 and p38

Author(s): Yung-Ming Chang | Ying-Ting Shih | Yueh-Sheng Chen | Chien-Liang Liu | Wen-Kuei Fang | Chang-Hai Tsai | Fuu-Jen Tsai | Wei-Wen Kuo | Tung-Yuan Lai | Chih-Yang Huang
Differential Cell Sensitivity between OTA and LPS upon Releasing TNF-α

Author(s): Lauy Al-Anati | Ebtisam Essid | Ulla Stenius | Knut Beuerlein | Klaus Schuh | Ernst Petzinger
Dual Effect of Neutrophils on pIgR/Secretory Component in Human Bronchial Epithelial Cells: Role of TGF-β

Author(s): Céline Ratajczak | Amélie Guisset | Bruno Detry | Yves Sibille | Charles Pilette
Cytosolic phospholipase A2 alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice

Author(s): Kishimoto Koji | Li Rung-Chi | Zhang Jian | Klaus Judith | Kibler Kathleen | Doré Sylvain | Koehler Raymond | Sapirstein Adam
Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis

Author(s): Kumar Pawan | Yadav Arti | Patel Samip | Islam Mozaffarul | Pan Quintin | Merajver Sofia | Teknos Theodoros
Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr-1 in rat hippocampal slices

Author(s): Kidambi Srivatsan | Yarmush Joel | Berdichevsky Yevgeny | Kamath Sangeetha | Fong Wayne | SchianodiCola Joseph
Pneumocystis cell wall β-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells

Author(s): Carmona Eva | Lamont Jeffrey | Xue Ailing | Wylam Mark | Limper Andrew
Differential Regulation of Gap Junction Proteins Connexin 40 and Connexin 43 in Cardiomyocytes

Author(s): A. Salameh | K. M�hlberg | P. Schneider | S. Dhein | D. Pfeiffer
TLR4 and Insulin Resistance

Author(s): Jane J. Kim | Dorothy D. Sears
Insilco binding analysis of MKP-1 inhibitors

Author(s): Sukesh K. | Lavanya C. | Balavinayagamani G.
Lipid Based Therapy for Ulcerative Colitis—Modulation of Intestinal Mucus Membrane Phospholipids as a Tool to Influence Inflammation

Author(s): Hannah Schneider | Annika Braun | Joachim Füllekrug | Wolfgang Stremmel | Robert Ehehalt
DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1

Author(s): Seidel Petra | Goulet Stephanie | Hostettler Katrin | Tamm Michael | Roth Michael
Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line

Author(s): Caccia Dario | Miccichè Francesca | Cassinelli Giuliana | Mondellini Piera | Casalini Patrizia | Bongarzone Italia
Macrophage migration inhibitory factor regulates interleukin-6 production by facilitating nuclear factor-kappa B activation during Vibrio vulnificus infection

Author(s): Chuang Chia-Chang | Chuang Yin-Ching | Chang Wen-Teng | Chen Chi-Chung | Hor Lien-I | Huang A-Ming | Choi Pui-Ching | Wang Chi-Yun | Tseng Po-Chin | Lin Chiou-Feng
Myricetin Protects Cells against Oxidative Stress-Induced Apoptosis via Regulation of PI3K/Akt and MAPK Signaling Pathways

Author(s): Kyoung Ah Kang | Zhi Hong Wang | Rui Zhang | Mei Jing Piao | Ki Cheon Kim | Sam Sik Kang | Young Woo Kim | Jongsung Lee | Deokhoon Park | Jin Won Hyun
Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action

Author(s): David Vauzour | Ana Rodriguez-Mateos | Giulia Corona | Maria Jose Oruna-Concha | Jeremy P. E. Spencer
Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models

Author(s): Yang Eun Jin | Jiang Jing Hua | Lee Sang Min | Yang Sun Choel | Hwang Hye Suk | Lee Myeong Soo | Choi Sun-Mi
Compound K, a Metabolite of Ginseng Saponin, Induces Mitochondria-Dependent and Caspase-Dependent Apoptosis via the Generation of Reactive Oxygen Species in Human Colon Cancer Cells

Author(s): In Kyung Lee | Kyoung Ah Kang | Chae Moon Lim | Ki Cheon Kim | Hee Sun Kim | Dong Hyun Kim | Bum Joon Kim | Weon Young Chang | Jae Hyuck Choi | Jin Won Hyun
Role of stellate cells in alcoholic liver fibrosis

Author(s): Krzysztof Plewka | Agnieszka Szuster-Ciesielska | Martyna Kandefer-Szerszeń
p38 and STAT3 activation by vGPCR in KSHV-infected cells

Author(s): Mingli Liu | Shanchun Guo
Selective p38α mitogen-activated protein kinase inhibitor attenuates lung inflammation and fibrosis in IL-13 transgenic mouse model of asthma

Author(s): Jing Ying Ma | Satyanarayana Medicherla | Irene Kerr | Ruban Mangadu | Andrew A Protter | Linda S Higgins
Apoptotic and chemotherapeutic properties of iron(III)-salophene in an ovarian cancer animal model

Author(s): Thilo S Lange | Carolyn McCourt | Rakesh K Singh | Kyu Kwang Kim | Ajay P Singh | et al
p38 MAPK inhibition reduces diabetes-induced impairment of wound healing

Author(s): Satyanarayana Medicherla | Scott Wadsworth | Breda Cullen | Derek Silcock | et al.
Tamm-Horsfall Glycoprotein Enhances PMN Phagocytosis by Binding to Cell Surface-Expressed Lactoferrin and Cathepsin G That Activates MAP Kinase Pathway

Author(s): Syue-Cian Siao | Ko-Jen Li | Song-Chou Hsieh | Cheng-Han Wu | Ming-Chi Lu | Chang-Youh Tsai | Chia-Li Yu
Expression and shedding of endothelial protein C receptor in prostate cancer cells

Author(s): Menschikowski Mario | Hagelgans Albert | Tiebel Oliver | Klinsmann Ludwig | Eisenhofer Graeme | Siegert Gabriele
A role for p38 MAPK in the regulation of ciliary motion in a eukaryote

Author(s): Ressurreição Margarida | Rollinson David | Emery Aidan | Walker Anthony
Evaluation of signal transduction pathways after transient cutaneous adenoviral gene delivery

Author(s): Steinstraesser Lars | Sorkin Michael | Jacobsen Frank | Al-Benna Sammy | Kesting Marco | Niederbichler Andreas | Otte Jan-Michel | Hirsch Tobias | Stupka Jadwiga | Steinau Hans-Ulrich | Schulte Matthias
The Vibrio parahaemolyticus Type III Secretion Systems manipulate host cell MAPK for critical steps in pathogenesis

Author(s): Matlawska-Wasowska Ksenia | Finn Rebecca | Mustel Ana | O'Byrne Conor | Baird Alan | Coffey Eleanor | Boyd Aoife
Diesel exhaust particles induce CYP1A1 and pro-inflammatory responses via differential pathways in human bronchial epithelial cells

Author(s): Totlandsdal Annike | Cassee Flemming | Schwarze Per | Refsnes Magne | Låg Marit
TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK

Author(s): Bakkebø Maren | Huse Kanutte | Hilden Vera | Smeland Erlend | Oksvold Morten
Defining the antigen receptor-dependent regulatory network that induces arrest of cycling immature B-lymphocytes

Author(s): Jamal Mohammad | Ravichandran Srikanth | Jailkhani Noor | Chatterjee Samrat | Dua Raina | Rao Kanury
Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro

Author(s): Furuya Ayako | Asano Kazuhito | Shoji Naruo | Hirano Kojiro | Hamasaki Taisuke | Suzaki Harumi
Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLC

Author(s): Ma Jun | Phillips Lynetta | Wang Ying | Dai Tiane | LaPage Janine | Natarajan Rama | Adler Sharon
Molecular mechanisms of liver preconditioning

Author(s): Elisa Alchera, Caterina Dal Ponte, Chiara Imarisio, Emanuele Albano, Rita Carini
Possible key residues that determine left gastric artery blood flow response to PACAP in dogs

Author(s): Mu-Xin Wei, Ping Hu, Ping Wang, Satoru Naruse, Kiyoshi Nokihara, Victor Wray, Tsuyoshi Ozaki
Olmesartan, an AT1 Antagonist, Attenuates Oxidative Stress, Endoplasmic Reticulum Stress and Cardiac Inflammatory Mediators in Rats with Heart Failure Induced by Experimental Autoimmune Myocarditis

Author(s): Vijayakumar Sukumaran, Kenichi Watanabe, Punniyakoti T. Veeraveedu, Narasimman Gurusamy, Meilei Ma, Rajarajan A. Thandavarayan, Arun Prasath Lakshmanan, Ken'ichi Yamaguchi, Kenji Suzuki, Makoto Kodama
To Die or to Survive, a Fatal Question for the Destiny of Prostate Cancer Cells after Androgen Deprivation Therapy

Author(s): Kai-Xin Zhang | Jessica Firus | Brenda Prieur | William Jia | Paul S. Rennie
Components of the mitogen-activated protein kinase cascade are activated in hepatic cells by Echinococcus multilocularis metacestode

Author(s): Ren-Yong Lin, Jun-Hua Wang, Xiao-Mei Lu, Xiao-Tao Zhou, Georges Mantion, Hao Wen, Dominique A Vuitton, Lysiane Richert
Potentially probiotic bacteria induce efficient maturation but differential cytokine production in human monocyte-derived dendritic cells

Author(s): Sinikka Latvala, Taija E Pietilä, Ville Veckman, Riina A Kekkonen, Soile Tynkkynen, Riitta Korpela, Ilkka Julkunen
FR167653, a p38 mitogen-activated protein kinase inhibitor, aggravates experimental colitis in mice

Author(s): Takashi Nishimura, Akira Andoh, Atsushi Nishida, Makoto Shioya, Yuhsuke Koizumi, Tomoyuki Tsujikawa, Yoshihide Fujiyama
Heterofucan from Sargassum filipendula Induces Apoptosis in HeLa Cells

Author(s): Leandro Silva Costa | Cinthia Beatrice Silva Telles | Ruth Medeiros Oliveira | Leonardo Thiago Duarte Barreto Nobre | Nednaldo Dantas-Santos | Rafael Barros Gomes Camara | Mariana Santana Santos Pereira Costa | Jailma Almeida-Lima | Raniere Fagundes Melo-Silveira | Ivan Rui Lopes Albuquerque | Edda Lisboa Leite | Hugo Alexandre Oliveira Rocha
Interferon alpha regulates MAPK and STAT1 pathways in human hepatoma cells

Author(s): Zhao Lan-Juan | Hua Xian | He Sheng-Fei | Ren Hao | Qi Zhong-Tian
The MAP kinase ERK and its scaffold protein MP1 interact with the chromatin regulator Corto during Drosophila wing tissue development

Author(s): Mouchel-Vielh Emmanuèle | Rougeot Julien | Decoville Martine | Peronnet Frédérique
Novel dinuclear platinum(II) complexes targets NFkappaB signaling pathway to induce apoptosis and inhibit metabolism of MCF-7 breast cancer cells.

Author(s): Bozena Popławska | Anna Bielawska | Arkadiusz Surazyński | Robert Czarnomysy | Krzysztof Bielawski
Identification of chosen apoptotic (TIAR and TIA-1) markers expression in thyroid tissues from adolescents with immune and non-immune thyroid diseases.

Author(s): A Bossowski | B Czarnocka | K Bardadin | A Moniuszko | A Łyczkowska | J Czerwinska | J Dadan | A Bossowska
Cardioprotective Effects of Telmisartan against Heart Failure in Rats Induced By Experimental Autoimmune Myocarditis through the Modulation of Angiotensin-Converting Enzyme-2/Angiotensin 1-7/Mas Receptor Axis

Author(s): Vijayakumar Sukumaran, Punniyakoti T. Veeraveedu, Narasimman Gurusamy, Ken'ichi Yamaguchi, Arun Prasath Lakshmanan, Meilei Ma, Kenji Suzuki, Makoto Kodama, Kenichi Watanabe
MIF Synergizes with Trypanosoma cruzi Antigens to Promote Efficient Dendritic Cell Maturation and IL-12 Production via p38 MAPK

Author(s): Cesar A. Terrazas, EriK Huitron, Alicia Vazquez, Imelda Juarez, Griselda M. Camacho, Elsa A. Calleja, Miriam Rodriguez-Sosa
The Increase in Mannose Receptor Recycling Favors Arginase Induction and Trypanosoma Cruzi Survival in Macrophages

Author(s): Vanina V. Garrido, Laura R. Dulgerian, Cinthia C. Stempin, Fabio M. Cerbán
Protein Kinases and Transcription Factors Activation in Response to UV-Radiation of Skin: Implications for Carcinogenesis

Author(s): César López-Camarillo | Elena Aréchaga Ocampo | Mavil López Casamichana | Carlos Pérez-Plasencia | Elizbeth Álvarez-Sánchez | Laurence A. Marchat
New Insights into the p38γ and p38δ MAPK Pathways

Author(s): Ana Risco | Ana Cuenda
Map4k4 a possible new biomarker in cancer therapy

Author(s): Laura Buburuzan | Catalina Luca
Olmesartan Attenuates the Impairment of Endothelial Cells Induced by Oxidized Low Density Lipoprotein through Downregulating Expression of LOX-1

Author(s): Hua Zhang | Genshan Ma | Yuyu Yao | Huidong Qian | Weizhang Li | Xinjun Chen | Wenlong Jiang | Ruolong Zheng
Nanostructured, Self-Assembling Peptide K5 Blocks TNF-α and PGE2 Production by Suppression of the AP-1/p38 Pathway

Author(s): Woo Seok Yang | Yung Chul Park | Ji Hye Kim | Hye Ri Kim | Tao Yu | Se Eun Byeon | Larry D. Unsworth | Jaehwi Lee | Jae Youl Cho
The Control of Human Immunosystem by Using Paeony Root Drug

Author(s): Hideo Tsuboi | Muhaimin Rifa’i | Khaled Hossain | Izumi Nakashima | Haruhiko Suzuki
Growth inhibition of a human colon carcinoma cell, COLO 201, by a natural product, Vitex agnus-castus fruits extract, in vivo and in vivo

Author(s): Takashi Oshima | Chieko Hirobe | Takahiro Hosoya | Hiroo Toyoda | Hiroshi Morita | Bo Yuan | Masahiko Imai | Hidetomo Kikuchi | Kunio Ohyama | Mai Saito
Growth inhibition of a human colon carcinoma cell, COLO 201, by a natural product, Vitex agnus-castus fruits extract, in vivo and in vivo

Author(s): Takashi Oshima | Chieko Hirobe | Takahiro Hosoya | Hiroo Toyoda | Hiroshi Morita | Bo Yuan | Masahiko Imai | Hidetomo Kikuchi | Kunio Ohyama | Mai Saito
C11 cyclopentenone from the ascidian Diplosoma sp. prevents epidermal growth factor-induced transformation of JB6 cells

Author(s): Sergey N. Fedorov | Sergey A. Dyshlovoy | Larisa K. Shubina | Alla Guzii | Alexandra S. Kuzmich | Tatyana N. Makarieva
El ácido acetilsalicílico inhibe la replicación del virus de la hepatitis a través de la vía de señalización de la ciclooxigena-2

Author(s): K. C. TRUJILLO MURILLO | F. J. BOSQUES PADILLA | JAVIER RAMOS JIM NEZ | H. G. MART NEZ RODR GUEZ | A. M. RIVAS ESTILLA
Comparative Analysis of Protein Expression Concomitant with DNA Methyltransferase 3A Depletion in a Melanoma Cell Line

Author(s): Xiaoyan Liu | Shengnan Tang | Tonghua Li | Haoyue Wang | Jiangming Sun | Qian Qiao | Jun Yao | Jian Fei
Map4k4 a possible new biomarker in cancer therapy

Author(s): Laura Buburuzan | Catalina Luca
Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV-1 transgenic rats

Author(s): Clary Caroline | Guidot Daniel | Bratina Margaux | Otis Jeffrey
Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3

Author(s): Porquet Nicolas | Poirier Andrée | Houle François | Pin Anne-Laure | Gout Stéphanie | Tremblay Pierre-Luc | Paquet Éric | Klinck Roscoe | Auger François | Huot Jacques
JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells

Author(s): Hsu Hsi-Hsien | Hu Wei-Syun | Lin Yueh-Min | Kuo Wei-Wen | Chen Li-Mien | Chen Wei-Kung | Hwang Jin-Ming | Tsai Fuu-Jen | Liu Chung-Jung | Huang Chih-Yang
Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain

Author(s): Sukhtankar Devki | Okun Alec | Chandramouli Anupama | Nelson Mark | Vanderah Todd | Cress Anne | Porreca Frank | King Tamara
Dopamine and α-synuclein dysfunction in Smad3 null mice

Author(s): Tapia-González Silvia | Giráldez-Pérez Rosa | Cuartero M Isabel | Casarejos M José | Mena M Ángeles | Wang Xiao-Fan | Sánchez-Capelo Amelia
Intracellular chloride regulates the G1/S cell cycle progression in gastric cancer cells

Author(s): Atsushi Shiozaki | Eigo Otsuji | Yoshinori Marunaka
Regulation of the arachidonic acid mobilization in macrophages by combustion-derived particles

Author(s): Fritsch-Decker Susanne | Both Tanja | Mülhopt Sonja | Paur Hanns-Rudolf | Weiss Carsten | Diabaté Silvia
C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

Author(s): Meyerowitz Jodi | Parker Sarah | Vella Laura | Ng Dominic | Price Katherine | Liddell Jeffrey | Caragounis Aphrodite | Li Qiao-Xin | Masters Colin | Nonaka Takashi | Hasegawa Masato | Bogoyevitch Marie | Kanninen Katja | Crouch Peter | White Anthony
Aspirin-triggered lipoxin A4 attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells

Author(s): Wang Yan-Ping | Wu Yan | Li Long-Yan | Zheng Jin | Liu Ren-Gang | Zhou Jie-Ping | Yuan Shi-Ying | Shang You | Yao Shang-Long
Resveratrol inhibits Cdk5 activity through regulation of p35 expression

Author(s): Utreras Elias | Terse Anita | Keller Jason | Iadarola Michael | Kulkarni Ashok
AGE-BSA down-regulates endothelial connexin43 gap junctions

Author(s): Wang Chi-Young | Liu Hung-Jen | Chen Heng-Ju | Lin Yi-Chun | Wang Hsueh-Hsiao | Hung Ta-Chuan | Yeh Hung-I
Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways

Author(s): Green Justin | Dholakia Shruti | Janczar Karolina | Ong Catherine | Moores Rachel | Fry Julie | Elkington Paul | Roncaroli Federico | Friedland Jon
Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury

Author(s): Zhou Fang | Onizawa Shigemitsu | Nagai Atsushi | Aoshiba Kazutetsu
Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord

Author(s): Lee Younglim | Pai Madhavi | Brederson Jill-Desiree | Wilcox Denise | Hsieh Gin | Jarvis Michael | Bitner Robert
Mitochondrial targeted catalase suppresses invasive breast cancer in mice

Author(s): Goh Jorming | Enns Linda | Fatemie Soroosh | Hopkins Heather | Morton John | Pettan-Brewer Christina | Ladiges Warren
Src mediates cytokine-stimulated gene expression in airway myocytes through ERK MAPK

Author(s): Singer Cherie | Lontay Beata | Unruh Helmut | Halayko Andrew | Gerthoffer William
Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation

Author(s): Hsieh Peiyuan | Hou Chien-Wei | Yao Pei-Wun | Wu Szu-Pei | Peng Yu-Fen | Shen Mei-Lin | Lin Ching-Huei | Chao Ya-Yun | Chang Ming-Hong | Jeng Kee-Ching
Intrathecal lidocaine pretreatment attenuates immediate neuropathic pain by modulating Nav1.3 expression and decreasing spinal microglial activation

Author(s): Cheng Kuang-I | Lai Chung-Sheng | Wang Fu-Yuan | Wang Hung-Chen | Chang Lin-Li | Ho Shung-Tai | Tsai Hung-Pei | Kwan Aij-Li
Melittin restores proteasome function in an animal model of ALS

Author(s): Yang Eun Jin | Kim Seon Hwy | Yang Sun Choel | Lee Sang Min | Choi Sun-Mi
Stanniocalcin-1 promotes tumor angiogenesis through up-regulation of VEGF in gastric cancer cells

Author(s): He Ling-fang | Wang Ting-ting | Gao Qian-ying | Zhao Guang-feng | Huang Ya-hong | Yu Li-ke | Hou Ya-yi
Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)

Author(s): Bachstetter Adam | Xing Bin | de Almeida Lucia | Dimayuga Edgardo | Watterson D Martin | Van Eldik Linda
Regulation of Autophagy by Kinases

Author(s): Savitha Sridharan | Kirti Jain | Alakananda Basu
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