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HER2/NEU AND TRASTUZUMAB

Author(s): María Jesús Coma del Corral | Martín de Frutos Herranz
HER2/NEU Y TRASTUZUMAB

Author(s): María Jesús Coma del Corral | Martín de Frutos Herranz
The UPS: a promising target for breast cancer treatment

Author(s): Sato Ko | Rajendra Eeson | Ohta Tomohiko
Lapatinib in the Treatment of Breast Cancer

Author(s): Hideko Yamauchi | Tiffany LaFortune | Naoto T. Ueno
Role of lapatinib in the first-line treatment of patients with metastatic breast cancer

Author(s): Catherine Oakman | Marta Pestrin | Elena Zafarana | et al
Targeted treatment of advanced and metastatic breast cancer with lapatinib

Author(s): Brendan Corkery | Norma O’Donovan | John Crown
Significant survival improvement of patients with recurrent breast cancer in the periods 2001-2008 vs. 1992-2000

Author(s): Shigematsu Hideo | Kawaguchi Hidetoshi | Nakamura Yoshiaki | Tanaka Kimihiro | Shiotani Satoko | Koga Chinami | Nishimura Sumiko | Taguchi Kenichi | Nishiyama Kenichi | Ohno Shinji
Delayed contrast enhancement cardiac magnetic resonance imaging in trastuzumab induced cardiomyopathy

Author(s): Fallah-Rad Nazanin | Lytwyn Matthew | Fang Tielan | Kirkpatrick Iain | Jassal Davinder
Trastuzumab: Is the new evidence revolutionary?

Author(s): Munshi Anusheel | Singh Pritanjali | Jalali Rakesh
2037 Delayed contrast enhancement cardiac magnetic resonance imaging IN trastuzumab induced cardiomyopathy

Author(s): Jassal Davinder | Fallah-Rad Nazanin | Lytwyn Matthew | Fang Tielan | Kirkpatrick Iain
The importance of antibody dependent cell-mediated cytotoxicity (ADCC) for breast cancer response to trastuzumab - Herceptin

Author(s): Juranić Zorica D. | Stanojević-Bakić Nevenka | Nešković-Konstantinović Zora | Žižak Željko | Stanojković Tatjana | Radulović Siniša S. | Milošević Dušanka
Development of automated brightfield double In Situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence In Situ hybridization (FISH)

Author(s): Nitta Hiroaki | Hauss-Wegrzyniak Beatrice | Lehrkamp Megan | Murillo Adrian | Gaire Fabien | Farrell Michael | Walk Eric | Penault-Llorca Frederique | Kurosumi Masafumi | Dietel Manfred | Wang Lin | Loftus Margaret | Pettay James | Tubbs Raymond | Grogan Thomas
Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability

Author(s): Lam Prudence | Burga Laura | Wu Bryan | Hofstatter Erin | Lu Kun | Wulf Gerburg
Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance

Author(s): Sahin Özgür | Fröhlich Holger | Löbke Christian | Korf Ulrike | Burmester Sara | Majety Meher | Mattern Jens | Schupp Ingo | Chaouiya Claudine | Thieffry Denis | Poustka Annemarie | Wiemann Stefan | Beissbarth Tim | Arlt Dorit
A prospective, non-randomized phase II trial of Trastuzumab and Capecitabine in patients with HER2 expressing metastasized pancreatic cancer

Author(s): Mihaljevic Andre | Büchler Peter | Harder Jan | Hofheinz Ralf | Gregor Michael | Kanzler Stephan | Schmiegel Wolff | Heinemann Volker | Endlicher Esther | Klöppel Günter | Seufferlein Thomas | Geissler Michael
State of the art of neoadjuvant chemotherapy in breast cancer: rationale, results and recent developments

Author(s): Honig, Arnd | Rieger, Lorenz | Sutterlin, Marc | Wallwiener, Diethelm | Dietl, Johannes | Solomayer, Erich-Franz
Radiation Recall Reaction Induced by Adjuvant Trastuzumab (Herceptin)

Author(s): Caroline Chung | David Stuart | Mira Keyes
Predicting for activity of second-line trastuzumab-based therapy in her2-positive advanced breast cancer

Author(s): Bartsch Rupert | De Vries Catharina | Pluschnig Ursula | Dubsky Peter | Bago-Horvath Zsuzsanna | Gampenrieder Simon | Rudas Margaretha | Mader Robert | Rottenfusser Andrea | Wiltschke Christoph | Gnant Michael | Zielinski Christoph | Steger Guenther
Deterministic Effects Propagation Networks for reconstructing protein signaling networks from multiple interventions

Author(s): Fröhlich Holger | Sahin Özgür | Arlt Dorit | Bender Christian | Beißbarth Tim
HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy

Author(s): McAlpine Jessica | Wiegand Kimberly | Vang Russell | Ronnett Brigitte | Adamiak Anna | Köbel Martin | Kalloger Steve | Swenerton Kenneth | Huntsman David | Gilks C | Miller Dianne
Differential survival following trastuzumab treatment based on quantitative HER2 expression and HER2 homodimers in a clinic-based cohort of patients with metastatic breast cancer

Author(s): Toi Masakazu | Sperinde Jeff | Huang Weidong | Saji Shigehira | Winslow John | Jin Xueguang | Tan Yuping | Ohno Shinji | Nakamura Seigo | Iwata Hiroji | Masuda Norikazu | Aogi Kenjiro | Morita Satoshi | Petropoulos Christos | Bates Michael
Trastuzumab with either docetaxel or vinorelbine as first-line treatment for patients with HER2-positive advanced breast cancer: a retrospective comparison

Author(s): Redana Stefania | Donadio Michela | Nolè Franco | Jacomuzzi Maria | Beano Alessandra | Martinello Rossella | Sapino Anna | Viale Giuseppe | Aglietta Massimo | Montemurro Filippo
The expression of TRMT2A, a novel cell cycle regulated protein, identifies a subset of breast cancer patients with HER2 over-expression that are at an increased risk of recurrence

Author(s): Hicks David | Janarthanan Bagi | Vardarajan Ramya | Kulkarni Swati | Khoury Thaer | Dim Daniel | Budd G | Yoder Brian | Tubbs Raymond | Schreeder Marshall | Estopinal Noel | Beck Rodney | Wang Yanling | Ring Brian | Seitz Robert | Ross Douglas
Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial

Author(s): Norell Håkan | Poschke Isabel | Charo Jehad | Wei Wei | Erskine Courtney | Piechocki Marie | Knutson Keith | Bergh Jonas | Lidbrink Elisabet | Kiessling Rolf
Recent Advances in Chemotherapy for Advanced Gastric Cancer

Author(s): Yoon-Koo Kang | Dok Hyun Yoon | Baek-Yeol Ryoo | Min-Hee Ryu
Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity

Author(s): Gunn Shelly | Yeh I-Tien | Lytvak Irina | Tirtorahardjo Budi | Dzidic Natasha | Zadeh Soheila | Kim Jaeweon | McCaskill Chris | Lim Lony | Gorre Mercedes | Mohammed Mansoor
HER2 testing on core needle biopsy specimens from primary breast cancers: interobserver reproducibility and concordance with surgically resected specimens

Author(s): Tsuda Hitoshi | Kurosumi Masafumi | Umemura Shinobu | Yamamoto Sohei | Kobayashi Takayuki | Osamura Robert
HER2/neu Immunostaining in Invasive Breast Cancer: Analysis of False Positive Factors

Author(s): Maha Arafah | Hala K. Kfoury | Shaesta N. Zaidi
Reduction of radiation pneumonitis by V20-constraints in breast cancer

Author(s): Goldman Ulla | Wennberg Berit | Svane Gunilla | Bylund Håkan | Lind Pehr
HER2 breast cancer therapies: a review

Author(s): Conleth G Murphy | Shanu Modi
Critical appraisal of trastuzumab in treatment of advanced stomach cancer

Author(s): Judith Meza-Junco | Heather-Jane Au | Michael B Sawyer
Recent advances in chemotherapy for advanced gastric cancer

Author(s): Jong Gwang Kim | Ho Young Chung | Wansik Yu
HER-2/neu immunoreactivity in invasive mammary carcinomas: a comparative study using monoclonal and polyclonal antibodies including the HercepTestTM

Author(s): Gouvêa Agostinho Pinto | Fernandes José Roberto Maggi | Olson Sandra Jean | Brandão Eduardo de Carvalho | Leite Miguel Torres | Gobbi Helenice
Cancer of the endometrium: current aspects of diagnostics and treatment

Author(s): Münstedt Karsten | Grant Phillip | Woenckhaus Joachim | Roth Gabriele | Tinneberg Hans-Rudolf
HER2 expression in cervical cancer as a potential therapeutic target

Author(s): Chavez-Blanco Alma | Perez-Sanchez Victor | Gonzalez-Fierro Aurora | Vela-Chavez Teresa | Candelaria Myrna | Cetina Lucely | Vidal Silvia | Dueñas-Gonzalez Alfonso
Analysis of trastuzumab and chemotherapy in advanced breast cancer after the failure of at least one earlier combination: An observational study

Author(s): Bartsch Rupert | Wenzel Catharina | Hussian Dagmar | Pluschnig Ursula | Sevelda Ursula | Koestler Wolfgang | Altorjai Gabriela | Locker Gottfried | Mader Robert | Zielinski Christoph | Steger Guenther
Vinorelbine plus 3-weekly trastuzumab in metastatic breast cancer: a single-centre phase 2 trial

Author(s): De Maio Ermelinda | Pacilio Carmen | Gravina Adriano | Morabito Alessandro | Di Rella Francesca | Labonia Vincenzo | Landi Gabriella | Nuzzo Francesco | Rossi Emanuela | Silvestro Pasqualina | Botti Gerardo | Di Bonito Maurizio | Curcio Maria | Formichelli Franca | La Vecchia Franca | Staiano Maria | Maurea Nicola | D'Aiuto Giuseppe | D'Aiuto Massimiliano | Thomas Renato | Signoriello Giuseppe | Perrone Francesco | de Matteis Andrea
Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells

Author(s): Menendez Javier | Vazquez-Martin Alejandro | Colomer Ramon | Brunet Joan | Carrasco-Pancorbo Alegria | Garcia-Villalba Rocio | Fernandez-Gutierrez Alberto | Segura-Carretero Antonio
FACTORES PRONOSTICOS DEL CANCER DE MAMA Y ONCOGEN HER2/NEU

Author(s): A. San Miguel | I. Gonzalez Blanco | R. García Iglesias | N. Alonso | A.B. Rodríguez Bujez | E.M. Martin Medrano | F.J. Martín Gil
External influences and priority-setting for anti-cancer agents: a case study of media coverage in adjuvant trastuzumab for breast cancer

Author(s): Booth Christopher | Dranitsaris George | Gainford M Corona | Berry Scott | Fralick Michael | Fralick John | Sue Joanna | Clemons Mark
Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: a meta-analysis of published randomized trials

Author(s): Viani Gustavo | Afonso Sergio | Stefano Eduardo | De Fendi Ligia | Soares Francisco
Long term disease-free survival and T cell and antibody responses in women with high-risk Her2+ breast cancer following vaccination against Her2

Author(s): Morse Michael | Hobeika Amy | Osada Takuya | Niedzwiecki Donna | Marcom Paul | Blackwell Kimberly | Anders Carey | Devi Gayathri | Lyerly H Kim | Clay Timothy
Bilateral synchronous breast carcinomas followed by a metastasis to the gallbladder: a case report

Author(s): Zagouri Flora | Sergentanis Theodoros | Koulocheri Dimitra | Nonni Afroditi | Bousiotou Aggeliki | Domeyer Philip | Michalopoulos Nikolaos | Dardamanis Dimitrios | Konstadoulakis Manousos | Zografos George
Drug waste minimisation and cost-containment in Medical Oncology: Two-year results of a feasibility study

Author(s): Fasola Gianpiero | Aita Marianna | Marini Luisa | Follador Alessandro | Tosolini Marina | Mattioni Laura | Mansutti Mauro | Piga Andrea | Brusaferro Silvio | Aprile Giuseppe
Correlation between NK function and response to trastuzumab in metastatic breast cancer patients

Author(s): Beano Alessandra | Signorino Elena | Evangelista Andrea | Brusa Davide | Mistrangelo Marinella | Polimeni Maria | Spadi Rosella | Donadio Michela | Ciuffreda Libero | Matera Lina
Vinorelbine-based salvage therapy in HER2-positive metastatic breast cancer patients progressing during trastuzumab-containing regimens: a retrospective study

Author(s): Montemurro Filippo | Redana Stefania | Nolè Franco | Donadio Michela | Jacomuzzzi Maria | Valabrega Giorgio | Viale Giuseppe | Sapino Anna | Aglietta Massimo
Pre-Clinical Assessment of 177Lu-Labeled Trastuzumab Targeting HER2 for Treatment and Management of Cancer Patients with Disseminated Intraperitoneal Disease

Author(s): Geoffrey L. Ray | Kwamena E. Baidoo | Lanea M. M. Keller | Paul S. Albert | Martin W. Brechbiel | Diane E. Milenic
89Zr-Radiolabeled Trastuzumab Imaging in Orthotopic and Metastatic Breast Tumors

Author(s): Albert J. Chang | Ravindra DeSilva | Sandeep Jain | Kimberley Lears | Buck Rogers | Suzanne Lapi
Cardiotoxicity of antineoplasic agents: onset, risk factors and clinical manifestation

Author(s): Maria L. Rădulescu | Caius L. Duncea | Dan Rădulescu | Valentin Militaru | Andreea Pârv
Successful Treatment of Recurrent Triple-Negative Breast Cancer with Combination of Targeted Therapies

Author(s): Stanislaw R. Burzynski | Alejandro Marquis | Eva Nagy-Kubove | Tomasz Janicki
Brain metastases from breast cancer: prognostic significance of HER-2 overexpression, effect of trastuzumab and cause of death

Author(s): Le Scodan Romuald | Jouanneau Ludivine | Massard Christophe | Gutierrez Maya | Kirova Youlia | Cherel Pascal | Gachet Julie | Labib Alain | Mouret-Fourme Emmanuelle
A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis

Author(s): Dearth Robert | Kuiatse Isere | Wang Yu-Fen | Liao Lan | Hilsenbeck Susan | Brown Powel | Xu Jianming | Lee Adrian
Is there any advantage to combined trastuzumab and chemotherapy in perioperative setting her 2neu positive localized gastric adenocarcinoma?

Author(s): Sbitti Yassir | Essaidi l Ismail | Debbagh Adil | Kadiri Habiba | Oukabli Mohamed | Moussaid Yassine | Slimani Khaoula | Fetohi Mohamed | Elkaoui Hakim | Albouzidi Abderrahmane | Mahi Mohamed | Ali Abdelmounaim | Ichou Mohamed | Errihani Hassan
The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity

Author(s): Dragowska Wieslawa | Weppler Sherry | Qadir Mohammed | Wong Ling | Franssen Yannick | Baker Jennifer | Kapanen Anita | Kierkels Guido | Masin Dana | Minchinton Andrew | Gelmon Karen | Bally Marcel
The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer

Author(s): Hahn Tobias | Bradley-Dunlop Deborah | Hurley Laurence | Von-Hoff Daniel | Gately Stephen | Mary Disis | Lu Hailing | Penichet Manuel | Besselsen David | Cole Brook | Meeuwsen Tanisha | Walker Edwin | Akporiaye Emmanuel
A case of HER-2-positive recurrent breast cancer showing a clinically complete response to trastuzumab-containing chemotherapy after primary treatment of triple-negative breast cancer

Author(s): Shigematsu Hideo | Kadoya Takayuki | Kobayashi Yoshie | Kajitani Keiko | Sasada Tatsunari | Emi Akiko | Masumoto Norio | Haruta Rumi | Kataoka Tsuyoshi | Oda Miyo | Arihiro Kouji | Okada Morihito
A new method for activity estimation in dosimetry of radiopharmaceuticals based on MRI imaging and magnetic nano particles

Author(s): Samira Rasaneh | Hossein Rajabi | Mohammad Hossein Babaei | Fariba Johari | Shahab Sheybani
Radioimmunotherapy of the mice bearing breast tumor with Herceptin labeled 177Lu

Author(s): Samira Rasaneh | Hossein Rajabi | Mohammad Hossein Babaei | Fariba Johari | Shahab Sheybani | Seyed Hasan Mirfallah | Mohamad Mazidi | Sepideh Khoshbakht | Yaser Tavakoli
Targeted delivery of doxorubicin-utilizing chitosan nanoparticles surface-functionalized with anti-Her2 trastuzumab

Author(s): Yousefpour P | Atyabi F | Vasheghani-Farahani E | Mousavi Movahedi AA | Dinarv | R
Immune Effects of Trastuzumab

Author(s): Marianna Nuti, Filippo Bellati, Valeria Visconti, Chiara Napoletano, Lavinia Domenici, Jlenia Caccetta, Ilaria Grazia Zizzari, Ilary Ruscito, Hassan Rahimi, Pierluigi Benedetti-Panici, Aurelia Rughetti
Healthcare costs in women with metastatic breast cancer receiving chemotherapy as their principal treatment modality

Author(s): Vera-Llonch Montserrat | Weycker Derek | Glass Andrew | Gao Sue | Borker Rohit | Qin Angie | Oster Gerry
PI3K pathway activation results in low efficacy of both trastuzumab and lapatinib

Author(s): Wang Leiping | Zhang Qunling | Zhang Jian | Sun Si | Guo Haiyi | Jia Zhen | Wang Biyun | Shao Zhimin | Wang Zhonghua | Hu Xichun
Specific antibody-receptor interactions trigger InlAB-independent uptake of listeria monocytogenes into tumor cell lines

Author(s): Heisig Martin | Frentzen Alexa | Bergmann Birgit | Galmbacher Katharina | Gentschev Ivaylo | Hotz Christian | Schoen Christoph | Stritzker Jochen | Fensterle Joachim | Rapp Ulf | Goebel Werner
HER2 splice variants and their relevance in breast cancer

Author(s): Marianna Sasso | Francesca Bianchi | Valentina Ciravolo | Elda Tagliabue | Manuela Campiglio
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