Ubiquitin domain proteins in disease

Author(s): Madsen Louise | Schulze Andrea | Seeger Michael | Hartmann-Petersen Rasmus

Patented small molecule inhibitors in the ubiquitin proteasome system

Author(s): Guédat Philippe | Colland Frédéric

Role of the ubiquitin system and tumor viruses in AIDS-related cancer

Author(s): Shackelford Julia | Pagano Joseph

Apoptosis induced by proteasome inhibition in human myoblast cultures

Author(s): J Sassone | A Ciammola | C Tiloca | M Glionna | G Meola | E Mancinelli | V Silani

The UPS: a promising target for breast cancer treatment

Author(s): Sato Ko | Rajendra Eeson | Ohta Tomohiko

Neuropathology and Therapeutic Intervention in Spinal and Bulbar Muscular Atrophy

Author(s): Haruhiko Banno | Masahisa Katsuno | Keisuke Suzuki | Fumiaki Tanaka | Gen Sobue

RNA interference of genes of ubiquitn and proteasome 7 subunit in cardiomyocytes culture

Author(s): Kyrychenko V. O. | Nagibin V. S. | Tumanovska L. V. | Rybalchenko V. K. | Dosenko V. E. | Moibenko O. O.

Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model

Author(s): Khandelwal Preeti | Dumanis Sonya | Feng Li | Maguire-Zeiss Kathleen | Rebeck GW | Lashuel Hilal | Moussa Charbel

Effects of ethanol on the proteasome interacting proteins

Author(s): Fawzia Bardag-Gorce

Cycle Inhibiting Factors (Cifs): Cyclomodulins That Usurp the Ubiquitin-Dependent Degradation Pathway of Host Cells

Author(s): Frédéric Taieb | Jean-Philippe Nougayrède | Eric Oswald

Domain analysis of the tubulin cofactor system: a model for tubulin folding and dimerization

Author(s): Grynberg Marcin | Jaroszewski Lukasz | Godzik Adam

Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase

Author(s): Heidrich Katja | Fraenkel Dan

A Method to Identify p62's UBA Domain Interacting Proteins

Author(s): Pridgeon Julia W. | Geetha Thangiah | Wooten Marie W.

Identification of Cellular Membrane Proteins Interacting with Hepatitis B Surface Antigen using Yeast Split-Ubiquitin System

Author(s): Toh Qi Chun | Tan Tuan Lin | Teo Wei Qiang | Ho Chin Yee | Parida Subhajeet | Chen Wei Ning

Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels

Author(s): Cope Gregory | Deshaies Raymond

UbiProt: a database of ubiquitylated proteins

Author(s): Chernorudskiy Alexander | Garcia Alejandro | Eremin Eugene | Shorina Anastasia | Kondratieva Ekaterina | Gainullin Murat

HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system

Author(s): DeHart Jason | Zimmerman Erik | Ardon Orly | Monteiro-Filho Carlos | Argañaraz Enrique | Planelles Vicente

Role of the ubiquitin proteasome system in Parkinson's disease

Author(s): Lim Kah-Leong | Tan Jeanne

Role of proteasomes in disease

Author(s): Dahlmann Burkhardt

Role of the ubiquitin proteasome system in renal cell carcinoma

Author(s): Corn Paul

The Role and Regulation of Receptor-Like Kinases in Plant Defense

Author(s): Kerry E. Goff | Katrina M. Ramonell

F-box proteins: more than baits for the SCF?

Author(s): Hermand Damien

Are heat shock proteins therapeutic target for Parkinson's disease?

Author(s): Guang-Rui Luo, Sheng Chen, Wei-Dong Le

Roles and potential therapeutic targets of the ubiquitin proteasome system in muscle wasting

Author(s): Nury David | Doucet Christine | Coux Olivier

The UPS in diabetes and obesity

Author(s): Wing Simon

The ubiquitin system, disease, and drug discovery

Author(s): Petroski Matthew

Targeting the UPS as therapy in multiple myeloma

Author(s): Chauhan Dharminder | Bianchi Giada | Anderson Kenneth

Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's disease

Author(s): Zetterberg Madeleine | Sjölander Annica | von Otter Malin | Palmér Mona | Landgren Sara | Minthon Lennart | Wallin Anders | Andreasen Niels | Blennow Kaj | Zetterberg Henrik

Poxvirus Exploitation of the Ubiquitin-Proteasome System

Author(s): Michele Barry | Nicholas van Buuren | Kristin Burles | Kelly Mottet | Qian Wang | Alastair Teale

Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon

Author(s): Kreidenweiss Andrea | Kremsner Peter | Mordmüller Benjamin

Exploring valid reference genes for gene expression studies in Brachypodium distachyon by real-time PCR

Author(s): Hong Shin-Young | Seo Pil | Yang Moon-Sik | Xiang Fengning | Park Chung-Mo

Molecular Pathology of Lewy Body Diseases

Author(s): Katrin Beyer | Montserrat Domingo-Sàbat | Aurelio Ariza

Nf-k B as Target of Pharmacological Treatment

Author(s): G.A. Scardina | A. Ruggieri | F. Carini | A. Cacioppo | V. Valenza | P. Messina

A novel Ecotin-Ubiquitin-Tag (ECUT) for efficient, soluble peptide production in the periplasm of Escherichia coli

Author(s): Paal Michael | Heel Thomas | Schneider Rainer | Auer Bernhard

A simple and high-sensitivity method for analysis of ubiquitination and polyubiquitination based on wheat cell-free protein synthesis

Author(s): Takahashi Hirotaka | Nozawa Akira | Seki Motoaki | Shinozaki Kazuo | Endo Yaeta | Sawasaki Tatsuya

A study on the functions of ubiquitin metabolic system related gene FBG2 in gastric cancer cell line

Author(s): Zhang Lin | Hou Yanhong | Wang Mengwei | Wu Benyan | Li Nan

plantsUPS: a database of plants' Ubiquitin Proteasome System

Author(s): Du Zhou | Zhou Xin | Li Li | Su Zhen

Selection of reference genes for quantitative real-time PCR expression studies in the apomictic and sexual grass Brachiaria brizantha

Author(s): Silveira Érica | Alves-Ferreira Márcio | Guimarães Larissa | da Silva Felipe | Carneiro Vera

Role of the Ubiquitin Proteasome System in Regulating Skin Pigmentation

Author(s): Hideya Ando | Masamitsu Ichihashi | Vincent J. Hearing

Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions

Author(s): Ushijima Yoko | Goshima Fumi | Kimura Hiroshi | Nishiyama Yukihiro

The replication stress response and the ubiquitin system: a new link in maintaining genomic integrity

Author(s): Koepp Deanna

Animal HECT ubiquitin ligases: evolution and functional implications

Author(s): Marín Ignacio

Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease

Author(s): Kajiwara Yuji | Franciosi Sonia | Takahashi Nagahide | Krug Lisa | Schmeidler James | Taddei Kevin | Haroutunian Vahram | Fried Ulrik | Ehrlich Michelle | Martins Ralph | Gandy Samuel | Buxbaum Joseph

Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development

Author(s): Tse William | Eisenhaber Birgit | Ho Steven | Ng Qimei | Eisenhaber Frank | Jiang Yun-Jin

MNF, an ankyrin repeat protein of myxoma virus, is part of a native cellular SCF complex during viral infection

Author(s): Blanié Sophie | Gelfi Jacqueline | Bertagnoli Stéphane | Camus-Bouclainville Christelle

Selection of reference genes for quantitative gene expression normalization in flax (Linum usitatissimum L.)

Author(s): Huis Rudy | Hawkins Simon | Neutelings Godfrey

Little ROCK is a ROCK1 pseudogene expressed in human smooth muscle cells

Author(s): Montefusco Maria Claudia | Merlo Kristen | Bryan Crystal | Surks Howard | Reis Steven | Mendelsohn Michael | Huggins Gordon

Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa

Author(s): Wei Li | Xu Wen | Deng Zhu | Su Zhen | Xue Yongbiao | Wang Tai

Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch

Author(s): Ushijima Yoko | Luo Chenhong | Kamakura Maki | Goshima Fumi | Kimura Hiroshi | Nishiyama Yukihiro

Coupling histone homeostasis to centromere integrity via the ubiquitin-proteasome system

Author(s): Takayama Yuko | Toda Takashi

Biolistic Mediated Sorghum (Sorghum bicolor L. Moench) Transformation via Mannose and Bialaphos Based Selection Systems

Author(s): A.W. Grootboom | N.L. Mkhonza | M.M. O`Kennedy | E. Chakauya | K. Kunert | R.K. Chikwamba

Antiviral Properties of ISG15

Author(s): Deborah J. Lenschow

The Nrf2 System as a Potential Target for the Development of Indirect Antioxidants

Author(s): Kyeong-Ah Jung | Mi-Kyoung Kwak

ProFITS of maize: a database of protein families involved in the transduction of signalling in the maize genome

Author(s): Ling Yi | Du Zhou | Zhang Zhenhai | Su Zhen

Neuroprotective Properties of Mildronate, a Small Molecule, in a Rat Model of Parkinson’s Disease

Author(s): Vija Z. Klusa | Sergejs Isajevs | Darja Svirina | Jolanta Pupure | Ulrika Beitnere | Juris Rumaks | Simons Svirskis | Baiba Jansone | Zane Dzirkale | Ruta Muceniece | Ivars Kalvinsh | Harry V. Vinters

The role of the proteasome for therapy of incurable diseases

Author(s): Irena Bubko | Beata M. Gruber | Elżbieta L. Anuszewska

Ancient origin of animal U-box ubiquitin ligases

Author(s): Marín Ignacio

Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast

Author(s): Gatti Laura | Hoe Kwang | Hayles Jacqueline | Righetti Sabina | Carenini Nives | Bo Laura | Kim Dong | Park Han | Perego Paola

Identification of genes differentially expressed during interaction of Mexican lime tree infected with "Candidatus Phytoplasma aurantifolia"

Author(s): Zamharir Maryam | Mardi Mohsen | Alavi Seyed | Hasanzadeh Nader | Nekouei Mojtaba | Zamanizadeh Hamid | Alizadeh Ali | Salekdeh Ghasem

A proteomic analysis of C-reactive protein stimulated THP-1 monocytes

Author(s): Eisenhardt Steffen | Habersberger Jonathon | Oliva Karen | Lancaster Graeme | Ayhan Mustafa | Woollard Kevin | Bannasch Holger | Rice Greg | Peter Karlheinz

Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes

Author(s): Grover Abhinav | Shandilya Ashutosh | Bisaria Virendra | Sundar Durai

NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

Author(s): Kwak Young-Don | Ma Tao | Diao Shiyong | Zhang Xue | Chen Yaomin | Hsu Janet | Lipton Stuart | Masliah Eliezer | Xu Huaxi | Liao Francesca-Fang

Peroxisome proliferator activated receptor-γ and the ubiquitin-proteasome system in colorectal cancer

Author(s): Ioannis A Voutsadakis

New Insights into the Role of the Ubiquitin-proteasome Pathway in the Regulation of Apoptosis

Author(s): Cui-Hua Liu | Alfred L. Goldberg | Xiao-Bo Qiu

Molecular Docking Studies of Type III Secretion System Effector Sopb Homolog in Vibrio vulnificus

Author(s): Indrani Karunasagar

Proteasome inhibition alleviates prolonged moderate compression-induced muscle pathology

Author(s): Siu Parco | Teng Bee | Pei Xiao | Tam Eric

Proteasome inhibitor treatment in alcoholic liver disease

Author(s): Fawzia Bardag-Gorce

Screening for suppressors of temperature sensitivity in a yeast mutant defective in vacuolar protein degradation

Author(s): Götte Martin

Interactions between co-expressed Arabidopsis sucrose transporters in the split-ubiquitin system

Author(s): Schulze Waltraud | Reinders Anke | Ward John | Lalonde Sylvie | Frommer Wolf

Cloning and functional characterisation of avian transcription factor E2A

Author(s): Conlon Thomas | Meyer Kerstin

Endoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expression

Author(s): Lu Min | Staszewski Lena | Echeverri Fernando | Xu Hong | Moyer Bryan

Methods designed for the identification and characterization of in vitro and in vivo chromatin assembly mutants in Saccharomyces cerevisiae

Author(s): Harkness Troy A. A. | Arnason Terra G. | Legrand Charmaine | Lone Ashley

Identification of α-type subunits of the Xenopus 20S proteasome and analysis of their changes during the meiotic cell cycle

Author(s): Wakata Yuka | Tokumoto Mika | Horiguchi Ryo | Ishikawa Katsutoshi | Nagahama Yoshitaka | Tokumoto Toshinobu

Quinone formation as dopaminergic neuron-specific oxidative stress in the pathogenesis of sporadic Parkinson's disease and neurotoxin-induced parkinsonism.

Author(s): Asanuma M | Miyazaki I | Diaz-Corrales FJ | Ogawa N

Arabidopsis ETO1 specifically interacts with and negatively regulates type 2 1-aminocyclopropane-1-carboxylate synthases

Author(s): Yoshida Hitoshi | Nagata Masayasu | Saito Koji | Wang Kevin | Ecker Joseph

Multiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5

Author(s): Doucet Christine | Gutierrez Gustavo | Lindon Catherine | Lorca Thierry | Lledo Gwendaline | Pinset Christian | Coux Olivier

Gain-of-Function Screen for Genes That Affect Drosophila Muscle Pattern Formation.

Author(s): Staudt Nicole | Molitor Andreas | Somogyi Kalman | Mata Juan | Curado Silvia | Eulenberg Karsten | Meise Martin | Siegmund Thomas | Häder Thomas | Hilfiker Andres | Brönner Günter | Ephrussi Anne | Rørth Pernille | Cohen Stephen M | Fellert Sonja | Chung Ho-Ryun | Piepenburg Olaf | Schäfer Ulrich | Jäckle Herbert | Vorbrüggen Gerd

Severe reversible cardiac failure after bortezomib treatment combined with chemotherapy in a non-small cell lung cancer patient: a case report

Author(s): Voortman Jens | Giaccone Giuseppe

The origin of introns and their role in eukaryogenesis: a compromise solution to the introns-early versus introns-late debate?

Author(s): Koonin Eugene

Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells

Author(s): Fujita Masatoshi

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability

Author(s): Shin Ju-Mi | Yoo Kyong-Jai | Kim Myung-Sun | Kim Dongku | Baek Kwang-Hyun

Alterations in lipid metabolism gene expression and abnormal lipid accumulation in fibroblast explants from giant axonal neuropathy patients

Author(s): Leung Conrad | Pang Yinghua | Shu Chang | Goryunov Dmitry | Liem Ronald

An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline

Author(s): Proctor Carole | Tsirigotis Maria | Gray Douglas

Amino acids and insulin act additively to regulate components of the ubiquitin-proteasome pathway in C2C12 myotubes

Author(s): Sadiq Fouzia | Hazlerigg David | Lomax Michael

The role of the UPS in cystic fibrosis

Author(s): Turnbull Emma | Rosser Meredith | Cyr Douglas

Role of the ubiquitin proteasome system in Alzheimer's disease

Author(s): Upadhya Sudarshan | Hegde Ashok

The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias

Author(s): Davies Janet | Sarkar Sovan | Rubinsztein David

Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes

Author(s): Cardozo Timothy | Pagano Michele

Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum

Author(s): Binette Julie | Dubé Mathieu | Mercier Johanne | Halawani Dalia | Latterich Martin | Cohen Éric

The possible role of the ubiquitin proteasome system in the development of atherosclerosis in diabetes

Author(s): Marfella Raffaele | D' Amico Michele | Di Filippo Clara | Siniscalchi Mario | sasso Ferdinando | Ferraraccio Franca | Rossi Francesco | Paolisso Giuseppe

The Role of the Ubiquitin-Proteasome System and p62 in the Development of Neurodegenerative Disease

Author(s): Michael G. Paine | Marie W. Wooten

Gene expression profile in obesity and type 2 diabetes mellitus

Author(s): Das Undurti | Rao Allam

The E3 ubiquitin ligase skp2 regulates neural differentiation independent from the cell cycle

Author(s): Boix-Perales Hector | Horan Ian | Wise Helen | Lin Horng-Ru | Chuang Li-Chiou | Yew P Renee | Philpott Anna

Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability

Author(s): Peth Andreas | Berndt Christoph | Henke Wolfgang | Dubiel Wolfgang

Discovery of genes implicated in whirling disease infection and resistance in rainbow trout using genome-wide expression profiling

Author(s): Baerwald Melinda | Welsh Amy | Hedrick Ronald | May Bernie

Intracellular delivery of peptides via association with ubiquitin or SUMO-1 coupled to protein transduction domains

Author(s): Vitte Anne-Laure | Jalinot Pierre

A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation

Author(s): Liu Qing | Lei Joy | Sikorska Marianna | Liu Rugao

Brain injury-associated biomarkers of TGF-beta1, S100B, GFAP, NF-L, tTG, AbetaPP, and tau were concomitantly enhanced and the UPS was impaired during acute brain injury caused by Toxocara canis in mice

Author(s): Liao Chien-Wei | Fan Chia-Kwung | Kao Ting-Chang | Ji Dar-Der | Su Kua-Eyre | Lin Yun-Ho | Cho Wen-Long

Multiple Interactions between Peroxisome Proliferators-Activated Receptors and the Ubiquitin-Proteasome System and Implications for Cancer Pathogenesis

Author(s): Davide Genini | Giuseppina M. Carbone | Carlo V. Catapano

Multiple Interactions between Peroxisome Proliferators-Activated Receptors and the Ubiquitin-Proteasome System and Implications for Cancer Pathogenesis

Author(s): Davide Genini | Giuseppina M. Carbone | Carlo V. Catapano

In silico Construction of phosphomannose isomerase (PMI) transformation vectors and evaluation of the effectiveness of vectors in tobacco (Nicotiana tabacum L.)

Author(s): Bohari Bahariah | Ghulam Kadir Ahmad Parveez | Mat Yunus Abdul Masani | Norzulaani Khalid

Developmental expression of p97/VCP (Valosin-containing protein) and Jab1/CSN5 in the rat testis and epididymis

Author(s): Cayli Sevil | Ocakli Seda | Erdemir Fikret | Tas Ufuk | Aslan Huseyin | Yener Tamer | Karaca Zafer

Selection of reference genes for quantitative real-time PCR expression studies of microdissected reproductive tissues in apomictic and sexual Boechera

Author(s): Pellino Marco | Sharbel Timothy | Mau Martin | Amiteye Samuel | Corral José

Potential prognostic marker ubiquitin carboxyl-terminal hydrolase-L1 does not predict patient survival in non-small cell lung carcinoma

Author(s): Orr Katy | Shi Zhanzhong | Brown W Mark | O'Hagan Kathleen | Lappin Terence | Maxwell Perry | Percy Melanie

Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation

Author(s): Ummanni Ramesh | Jost Edgar | Braig Melanie | Lohmann Frithjof | Mundt Frederike | Barett Christine | Schlomm Thorsten | Sauter Guido | Senff Tina | Bokemeyer Carsten | Sültmann Holger | Meyer-Schwesinger Catherine | Brümmendorf Tim | Balabanov Stefan

Dopamine and α-synuclein dysfunction in Smad3 null mice

Author(s): Tapia-González Silvia | Giráldez-Pérez Rosa | Cuartero M Isabel | Casarejos M José | Mena M Ángeles | Wang Xiao-Fan | Sánchez-Capelo Amelia

Microarray analysis of peripheral blood lymphocytes from ALS patients and the SAFE detection of the KEGG ALS pathway

Author(s): Mougeot Jean-Luc | Li Zhen | Price Andrea | Wright Fred | Brooks Benjamin

Intraperitoneal Oxygen/Ozone Treatment Decreases the Formation of Experimental Postsurgical Peritoneal Adhesions and the Levels/Activity of the Local Ubiquitin-Proteasome System

Author(s): Clara Di Filippo | Annalisa Capuano | Barbara Rinaldi | Margherita Luongo | Biagio Lettieri | Francesco Rossi | Michele D'Amico

Quantitative characterization and analysis of the dynamic NF-κB response in microglia

Author(s): Sheppard Patrick | Sun Xiaoyun | Emery John | Giffard Rona | Khammash Mustafa

Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice

Author(s): Ganay Thibault | Boizot Alexia | Burrer Renaud | Chauvin Jean | Bomont Pascale

Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH

Author(s): Christian Perry | Fiandalo Michael | Schwarze Steven

Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

Author(s): Meng Fanjun | Yao Dongdong | Shi Yang | Kabakoff Jonathan | Wu Wei | Reicher Joshua | Ma Yuliang | Moosmann Bernd | Masliah Eliezer | Lipton Stuart | Gu Zezong

Insulin alleviates degradation of skeletal muscle protein by inhibiting the ubiquitin-proteasome system in septic rats

Author(s): Chen Qiyi | Li Ning | Zhu Weiming | Li Weiqin | Tang Shaoqiu | Yu Wenkui | Gao Tao | Zhang Juanjuan | Li Jieshou

Pros and cons of a prion-like pathogenesis in Parkinson's disease

Author(s): Hilker Ruediger | Brotchie Jonathan | Chapman Joab

Mathematical model for the ubiquitin activating enzyme E1

Author(s): Francisco Javier López-Cánovas | Francisca Cánovas | María Antonia Günther Sillero | Antonio Sillero