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Molecular Neurodegeneration

ISSN: 1750--1326
Publisher: BioMed Central


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BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina

Author(s): Harder Jeffrey | Libby Richard
Volume: 6
Issue: 1
Year: 2011
Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease

Author(s): Pan Xiao-dong | Zhu Yuan-gui | Lin Nan | Zhang Jing | Ye Qin-yong | Huang Hua-pin | Chen Xiao-chun
Volume: 6
Issue: 1
Year: 2011
Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons

Author(s): Jung Cha-Gyun | Uhm Kyung-Ok | Miura Yutaka | Hosono Takashi | Horike Hirofumi | Khanna Kum | Kim Mi-Jeong | Michikawa Makoto
Volume: 6
Issue: 1
Year: 2011
Protein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degeneration

Author(s): Asaithambi Arunkumar | Kanthasamy Arthi | Saminathan Hariharan | Anantharam Vellareddy | Kanthasamy Anumantha
Volume: 6
Issue: 1
Year: 2011
Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats

Author(s): Kitamura Yoshihisa | Watanabe Shotaro | Taguchi Masanobu | Takagi Kentaro | Kawata Takuya | Takahashi-Niki Kazuko | Yasui Hiroyuki | Maita Hiroshi | Iguchi-Ariga Sanae | Ariga Hiroyoshi
Volume: 6
Issue: 1
Year: 2011
Disruption of the NF-κB/IκBα Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons

Author(s): Shim David | Yang Li | Reed J | Noebels Jeffrey | Chiao Paul | Zheng Hui
Volume: 6
Issue: 1
Year: 2011
Pleiotrophin over-expression provides trophic support to dopaminergic neurons in parkinsonian rats

Author(s): Taravini Irene | Chertoff Mariela | Cafferata Eduardo | Courty José | Murer Mario | Pitossi Fernando | Gershanik Oscar
Volume: 6
Issue: 1
Year: 2011
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

Author(s): Lasagna-Reeves Cristian | Castillo-Carranza Diana | Sengupta Urmi | Clos Audra | Jackson George | Kayed Rakez
Volume: 6
Issue: 1
Year: 2011
Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons

Author(s): Liang Qiuli | Ouyang Xiaosen | Schneider Lonnie | Zhang Jianhua
Volume: 6
Issue: 1
Year: 2011
Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo

Author(s): Altmeppen Hermann | Prox Johannes | Puig Berta | Kluth Mark | Bernreuther Christian | Thurm Dana | Jorissen Ellen | Petrowitz Bettina | Bartsch Udo | De Strooper Bart | Saftig Paul | Glatzel Markus
Volume: 6
Issue: 1
Year: 2011
Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus

Author(s): Marwarha Gurdeep | Prasanthi Jaya | Schommer Jared | Dasari Bhanu | Ghribi Othman
Volume: 6
Issue: 1
Year: 2011
Anchored FRET sensors detect local caspase activation prior to neuronal degeneration

Author(s): Figueroa Ricardo | Ramberg Veronica | Gatsinzi Tom | Samuelsson Malin | Zhang Mu | Iverfeldt Kerstin | Hallberg Einar
Volume: 6
Issue: 1
Year: 2011
Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease

Author(s): Simmons Christopher | Zou Fanggeng | Younkin Steven | Estus Steven
Volume: 6
Issue: 1
Year: 2011
DJ-1 can inhibit microtubule associated protein 1 B formed aggregates

Author(s): Wang Zhiquan | Zhang Yu | Zhang Shi | Guo Qianqian | Tan Yuyan | Wang Xinyi | Xiong Ran | Ding Jianqing | Chen Shengdi
Volume: 6
Issue: 1
Year: 2011
Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

Author(s): Meng Fanjun | Yao Dongdong | Shi Yang | Kabakoff Jonathan | Wu Wei | Reicher Joshua | Ma Yuliang | Moosmann Bernd | Masliah Eliezer | Lipton Stuart | Gu Zezong
Volume: 6
Issue: 1
Year: 2011
PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease

Author(s): Taherzadeh-Fard Elahe | Saft Carsten | Akkad Denis | Wieczorek Stefan | Haghikia Aiden | Chan Andrew | Epplen Jörg | Arning Larissa
Volume: 6
Issue: 1
Year: 2011
Gene expression endophenotypes: a novel approach for gene discovery in Alzheimer's disease

Author(s): Ertekin-Taner Nilüfer
Volume: 6
Issue: 1
Year: 2011
Similarities and differences in structure, expression, and functions of VLDLR and ApoER2

Author(s): Reddy Sunil | Connor Teal | Weeber Edwin | Rebeck William
Volume: 6
Issue: 1
Year: 2011
Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis

Author(s): Ren Guijie | Ma Zhongcai | Hui Maria | Kudo Lili | Hui Koon-Sea | Karsten Stanislav
Volume: 6
Issue: 1
Year: 2011
Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease

Author(s): Hracskó Zsuzsanna | Baranyi Mária | Csölle Cecilia | Gölöncsér Flóra | Madarász Emilia | Kittel Ágnes | Sperlágh Beáta
Volume: 6
Issue: 1
Year: 2011
A mutation in the dynein heavy chain gene compensates for energy deficit of mutant SOD1 mice and increases potentially neuroprotective IGF-1

Author(s): Fergani Anissa | Eschbach Judith | Oudart Hugues | Larmet Yves | Schwalenstocker Birgit | Ludolph Albert | Loeffler Jean-Philippe | Dupuis Luc
Volume: 6
Issue: 1
Year: 2011
Biology and pathophysiology of the amyloid precursor protein

Author(s): Zheng Hui | Koo Edward
Volume: 6
Issue: 1
Year: 2011
Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice

Author(s): Ganay Thibault | Boizot Alexia | Burrer Renaud | Chauvin Jean | Bomont Pascale
Volume: 6
Issue: 1
Year: 2011
An organotypic slice culture model of chronic white matter injury with maturation arrest of oligodendrocyte progenitors

Author(s): Dean Justin | Riddle Art | Maire Jennifer | Hansen Kelly | Preston Marnie | Barnes Anthony | Sherman Larry | Back Stephen
Volume: 6
Issue: 1
Year: 2011
C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

Author(s): Meyerowitz Jodi | Parker Sarah | Vella Laura | Ng Dominic | Price Katherine | Liddell Jeffrey | Caragounis Aphrodite | Li Qiao-Xin | Masters Colin | Nonaka Takashi | Hasegawa Masato | Bogoyevitch Marie | Kanninen Katja | Crouch Peter | White Anthony
Volume: 6
Issue: 1
Year: 2011
A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection

Author(s): L'Episcopo Francesca | Serapide Maria | Tirolo Cataldo | Testa Nunzio | Caniglia Salvatore | Morale Maria | Pluchino Stefano | Marchetti Bianca
Volume: 6
Issue: 1
Year: 2011
Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism

Author(s): Yelamanchili Sowmya | Chaudhuri Amrita | Flynn Claudia | Fox Howard
Volume: 6
Issue: 1
Year: 2011
Mutant Prpf31 causes pre-mRNA splicing defects and rod photoreceptor cell degeneration in a zebrafish model for Retinitis pigmentosa

Author(s): Yin Jun | Brocher Jan | Fischer Utz | Winkler Christoph
Volume: 6
Issue: 1
Year: 2011
Replication of EPHA1 and CD33 associations with late-onset Alzheimer's disease: a multi-centre case-control study

Author(s): Carrasquillo Minerva | Belbin Olivia | Hunter Talisha | Ma Li | Bisceglio Gina | Zou Fanggeng | Crook Julia | Pankratz V | Sando Sigrid | Aasly Jan | Barcikowska Maria | Wszolek Zbigniew | Dickson Dennis | Graff-Radford Neill | Petersen Ronald | Passmore Peter | Morgan Kevin | Younkin Steven
Volume: 6
Issue: 1
Year: 2011
Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

Author(s): Zhao Wei | Varghese Merina | Yemul Shrishailam | Pan Yong | Cheng Alice | Marano Paul | Hassan Sadiq | Vempati Prashant | Chen Fei | Qian Xianjuan | Pasinetti Giulio
Volume: 6
Issue: 1
Year: 2011
Bovine spongiform encephalopathy infection alters endogenous retrovirus expression in distinct brain regions of cynomolgus macaques (Macaca fascicularis)

Author(s): Greenwood Alex | Vincendeau Michelle | Schmädicke Ann-Christin | Montag Judith | Seifarth Wolfgang | Motzkus Dirk
Volume: 6
Issue: 1
Year: 2011
Dopamine and α-synuclein dysfunction in Smad3 null mice

Author(s): Tapia-González Silvia | Giráldez-Pérez Rosa | Cuartero M Isabel | Casarejos M José | Mena M Ángeles | Wang Xiao-Fan | Sánchez-Capelo Amelia
Volume: 6
Issue: 1
Year: 2011
Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity

Author(s): Xifró Xavier | Anglada-Huguet Marta | Rué Laura | Saavedra Ana | Pérez-Navarro Esther | Alberch Jordi
Volume: 6
Issue: 1
Year: 2011
Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice

Author(s): Xu Ya-Fei | Zhang Yong-Jie | Lin Wen-Lang | Cao Xiangkun | Stetler Caroline | Dickson Dennis | Lewis Jada | Petrucelli Leonard
Volume: 6
Issue: 1
Year: 2011
Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease

Author(s): Jiang Hong | Hampel Harald | Prvulovic David | Wallin Anders | Blennow Kaj | Li Rena | Shen Yong
Volume: 6
Issue: 1
Year: 2011
Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

Author(s): Giralt Albert | Carretón Olga | Lao-Peregrin Cristina | Martín Eduardo | Alberch Jordi
Volume: 6
Issue: 1
Year: 2011
Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo

Author(s): Jullienne Amandine | Montagne Axel | Orset Cyrille | Lesept Flavie | Jane David | Monaghan Daniel | Maubert Eric | Vivien Denis | Ali Carine
Volume: 6
Issue: 1
Year: 2011
Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders

Author(s): Crews Leslie | Ruf Rebecca | Patrick Christina | Dumaop Wilmar | Trejo-Morales Margarita | Achim Cristian | Rockenstein Edward | Masliah Eliezer
Volume: 6
Issue: 1
Year: 2011
Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function

Author(s): Delay Charlotte | Calon Frédéric | Mathews Paul | Hébert Sébastien
Volume: 6
Issue: 1
Year: 2011
Decreased expression of B cell related genes in leukocytes of women with Parkinson's disease

Author(s): Kedmi Merav | Bar-Shira Anat | Gurevich Tanya | Giladi Nir | Orr-Urtreger Avi
Volume: 6
Issue: 1
Year: 2011
Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

Author(s): Grabrucker Andreas | Schmeisser Michael | Udvardi Patrick | Arons Magali | Schoen Michael | Woodling Nathaniel | Andreasson Katrin | Hof Patrick | Buxbaum Joseph | Garner Craig | Boeckers Tobias
Volume: 6
Issue: 1
Year: 2011
Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease

Author(s): Carroll Jeffrey | Southwell Amber | Graham Rona | Lerch Jason | Ehrnhoefer Dagmar | Cao Li-Ping | Zhang Wei-Ning | Deng Yu | Bissada Nagat | Henkelman R | Hayden Michael
Volume: 6
Issue: 1
Year: 2011
Alzheimer's disease: synapses gone cold

Author(s): Koffie Robert | Hyman Bradley | Spires-Jones Tara
Volume: 6
Issue: 1
Year: 2011
A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo

Author(s): Fonte Virginia | Dostal Vishantie | Roberts Christine | Gonzales Patrick | Lacor Pascale | Magrane Jordi | Dingwell Natalie | Fan Emily | Silverman Michael | Stein Gretchen | Link Christopher
Volume: 6
Issue: 1
Year: 2011
Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons

Author(s): Pugazhenthi Subbiah | Wang Maorong | Pham Serena | Sze Chun-I | Eckman Christopher
Volume: 6
Issue: 1
Year: 2011
TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6

Author(s): Fiesel Fabienne | Schurr Christine | Weber Stephanie | Kahle Philipp
Volume: 6
Issue: 1
Year: 2011
Autoimmune-induced preferential depletion of myelin-associated glycoprotein (MAG) is genetically regulated in relapsing EAE (B6 × SJL) F1 mice

Author(s): Skundric Dusanka | Dai Rujuan | Zakarian Vaagn | Zhou Weili
Volume: 3
Issue: 1
Year: 2008
Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1

Author(s): Carter Donald | Dunn Edwige | Pauley Adele | McKinley Denise | Fleck Timothy | Ellerbrook Brenda | Stratman Nancy | Zhou Xiangdong | Himes Carol | Nye Jeffrey | Tomasselli Alfredo | Yan Riqiang
Volume: 3
Issue: 1
Year: 2008
Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein

Author(s): Zerbinatti Celina | Cordy Joanna | Chen Ci-Di | Guillily Maria | Suon Sokreine | Ray William | Seabrook Guy | Abraham Carmela | Wolozin Benjamin
Volume: 3
Issue: 1
Year: 2008
Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons

Author(s): Wang Danling | Tang Beisha | Zhao Guohua | Pan Qian | Xia Kun | Bodmer Rolf | Zhang Zhuohua
Volume: 3
Issue: 1
Year: 2008
A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation

Author(s): Liu Qing | Lei Joy | Sikorska Marianna | Liu Rugao
Volume: 3
Issue: 1
Year: 2008
Ginkgolides protect against amyloid-β1–42-mediated synapse damage in vitro

Author(s): Bate Clive | Tayebi Mourad | Williams Alun
Volume: 3
Issue: 1
Year: 2008
Presenilins are required for maintenance of neural stem cells in the developing brain

Author(s): Kim Woo-Young | Shen Jie
Volume: 3
Issue: 1
Year: 2008
Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding

Author(s): Ikin Annat | Causevic Mirsada | Pedrini Steve | Benson Lyndsey | Buxbaum Joseph | Suzuki Toshiharu | Lovestone Simon | Higashiyama Shigeki | Mustelin Tomas | Burgoyne Robert | Gandy Sam
Volume: 2
Issue: 1
Year: 2007
Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene

Author(s): Wishart Thomas | MacDonald Stephen | Chen Philip | Shipston Michael | Coleman Michael | Gillingwater Thomas | Ribchester Richard
Volume: 2
Issue: 1
Year: 2007
Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

Author(s): Kayed Rakez | Head Elizabeth | Sarsoza Floyd | Saing Tommy | Cotman Carl | Necula Mihaela | Margol Lawrence | Wu Jessica | Breydo Leonid | Thompson Jennifer | Rasool Suhail | Gurlo Tatyana | Butler Peter | Glabe Charles
Volume: 2
Issue: 1
Year: 2007
Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau

Author(s): Santa-Maria Ismael | Hernández Félix | Del Rio Joaquín | Moreno Francisco | Avila Jesús
Volume: 2
Issue: 1
Year: 2007
An AICD-based functional screen to identify APP metabolism regulators

Author(s): Zhang Can | Khandelwal Preeti | Chakraborty Ranjita | Cuellar Trinna | Sarangi Srikant | Patel Shyam | Cosentino Christopher | O'Connor Michael | Lee Jeremy | Tanzi Rudolph | Saunders Aleister
Volume: 2
Issue: 1
Year: 2007
Design of an improved set of oligonucleotide primers for genotyping MeCP2tm1.1Bird KO mice by PCR

Author(s): Miralvès Julie | Magdeleine Eddy | Joly Etienne
Volume: 2
Issue: 1
Year: 2007
ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity

Author(s): Fuentealba Rodrigo | Barría Maria | Lee Jiyeon | Cam Judy | Araya Claudia | Escudero Claudia | Inestrosa Nibaldo | Bronfman Francisca | Bu Guojun | Marzolo Maria-Paz
Volume: 2
Issue: 1
Year: 2007
Tau phosphorylation by GSK-3β promotes tangle-like filament morphology

Author(s): Rankin Carolyn | Sun Qian | Gamblin Truman
Volume: 2
Issue: 1
Year: 2007
Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Aβ levels

Author(s): Lawlor Patricia | Bland Ross | Das Pritam | Price Robert | Holloway Vallie | Smithson Lisa | Dicker Bridget | During Matthew | Young Deborah | Golde Todd
Volume: 2
Issue: 1
Year: 2007
Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons

Author(s): Gong Jian-Sheng | Morita Shin-ya | Kobayashi Mariko | Handa Tetsurou | Fujita Shinobu | Yanagisawa Katsuhiko | Michikawa Makoto
Volume: 2
Issue: 1
Year: 2007
Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease

Author(s): Gu Xiaofeng | André Véronique | Cepeda Carlos | Li Shi-Hua | Li Xiao-Jiang | Levine Michael | Yang X William
Volume: 2
Issue: 1
Year: 2007
Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease

Author(s): Stobart Michael | Parchaliuk Debra | Simon Sharon | LeMaistre Jillian | Lazar Jozef | Rubenstein Richard | Knox J David
Volume: 2
Issue: 1
Year: 2007
Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms

Author(s): Wahrle Suzanne | Shah Aarti | Fagan Anne | Smemo Scott | Kauwe John | Grupe Andrew | Hinrichs Anthony | Mayo Kevin | Jiang Hong | Thal Leon | Goate Alison | Holtzman David
Volume: 2
Issue: 1
Year: 2007
Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism

Author(s): Vetrivel Kulandaivelu | Gong Ping | Bowen James | Cheng Haipeng | Chen Ying | Carter Meghan | Nguyen Phuong | Placanica Lisa | Wieland Felix | Li Yue-Ming | Kounnas Maria | Thinakaran Gopal
Volume: 2
Issue: 1
Year: 2007
Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra

Author(s): Grammatopoulos Tom | Jones Susan | Ahmadi Ferogh | Hoover Brian | Snell Lawrence | Skoch Jesse | Jhaveri Vimal | Poczobutt Andy | Weyhenmeyer James | Zawada W Michael
Volume: 2
Issue: 1
Year: 2007
Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo

Author(s): Chakrabarty Paramita | Herring Amanda | Ceballos-Diaz Carolina | Das Pritam | Golde Todd
Volume: 6
Issue: 1
Year: 2011
TRPM8 and Nav1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons

Author(s): Gasperini Robert | Hou Xu | Parkington Helena | Coleman Harry | Klaver David | Vincent Adele | Foa Lisa | Small David
Volume: 6
Issue: 1
Year: 2011
Differential regulation of BACE1 expression by oxidative and nitrosative signals

Author(s): Kwak Young-Don | Wang Ruishan | Li Jing | Zhang Yun-Wu | Xu Huaxi | Liao Francesca-Fang
Volume: 6
Issue: 1
Year: 2011
A new role for interferon gamma in neural stem/precursor cell dysregulation

Author(s): Walter Janine | Honsek Silke | Illes Sebastian | Wellen Jennifer | Hartung Hans-Peter | Rose Christine | Dihné Marcel
Volume: 6
Issue: 1
Year: 2011
Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse

Author(s): Takamura Ayumi | Okamoto Yasuhide | Kawarabayashi Takeshi | Yokoseki Tatsuki | Shibata Masao | Mouri Akihiro | Nabeshima Toshitaka | Sun Hui | Abe Koji | Urisu Tsuneo | Yamamoto Naoki | Shoji Mikio | Yanagisawa Katsuhiko | Michikawa Makoto | Matsubara Etsuro
Volume: 6
Issue: 1
Year: 2011
Transcriptional Regulation of TMP21 by NFAT

Author(s): Liu Shengchun | Zhang Si | Bromley-Brits Kelley | Cai Fang | Zhou Weihui | Xia Kun | Mittelholtz Jill | Song Weihong
Volume: 6
Issue: 1
Year: 2011
Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction

Author(s): Abdul Muneer P | Alikunju Saleena | Szlachetka Adam | Murrin L Charles | Haorah James
Volume: 6
Issue: 1
Year: 2011
Generation and Characterization of a genetic zebrafish model of SMA carrying the human SMN2 gene

Author(s): Hao Le | Burghes Arthur | Beattie Christine
Volume: 6
Issue: 1
Year: 2011
NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

Author(s): Kwak Young-Don | Ma Tao | Diao Shiyong | Zhang Xue | Chen Yaomin | Hsu Janet | Lipton Stuart | Masliah Eliezer | Xu Huaxi | Liao Francesca-Fang
Volume: 5
Issue: 1
Year: 2010
Age-related synaptic loss of the medial olivocochlear efferent innervation

Author(s): Fu Benjamin | Le Prell Colleen | Simmons Dwayne | Lei Debin | Schrader Angela | Chen Amelia | Bao Jianxin
Volume: 5
Issue: 1
Year: 2010
ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics

Author(s): Lee Shuchen | Yang Guang | Yong Yue | Liu Ying | Zhao Liyun | Xu Jing | Zhang Xiaomin | Wan Yanjie | Feng Chun | Fan Zhiqin | Liu Yong | Luo Jia | Ke Zun-Ji
Volume: 5
Issue: 1
Year: 2010
ER stress response plays an important role in aggregation of α-synuclein

Author(s): Jiang Peizhou | Gan Ming | Ebrahim Abdul | Lin Wen-Lang | Melrose Heather | Yen Shu-Hui
Volume: 5
Issue: 1
Year: 2010
Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans

Author(s): Keowkase Roongpetch | Aboukhatwa Marwa | Adam Bao-Ling | Beach J Warren | Terry Alvin | Buccafussco Jerry | Luo Yuan
Volume: 5
Issue: 1
Year: 2010
α-synuclein induced synapse damage is enhanced by amyloid-β1-42

Author(s): Bate Clive | Gentleman Steve | Williams Alun
Volume: 5
Issue: 1
Year: 2010
DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease

Author(s): Chen Jianmin | Cohen Mark | Lerner Alan | Yang Yan | Herrup Karl
Volume: 5
Issue: 1
Year: 2010
Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors

Author(s): Kegel Kimberly | Sapp Ellen | Alexander Jonathan | Reeves Patrick | Bleckmann Dorothee | Sobin Linsday | Masso Nicholas | Valencia Antonio | Jeong Hyunkyung | Krainc Dimitri | Palacino James | Curtis Daniel | Kuhn Rainer | Betschart Claudia | Sena-Esteves Miguel | Aronin Neil | Paganetti Paolo | DiFiglia Marian
Volume: 5
Issue: 1
Year: 2010
Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

Author(s): Kayed Rakez | Canto Isabel | Breydo Leonid | Rasool Suhail | Lukacsovich Tamas | Wu Jessica | Albay Ricardo | Pensalfini Anna | Yeung Stephen | Head Elizabeth | Marsh J Lawrence | Glabe Charles
Volume: 5
Issue: 1
Year: 2010
Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease

Author(s): Che Hong Van | Metzger Silke | Portal Esteban | Deyle Carolin | Riess Olaf | Nguyen Huu
Volume: 6
Issue: 1
Year: 2011
Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit

Author(s): Gersbacher Manuel | Kim Doo | Bhattacharyya Raja | Kovacs Dora
Volume: 5
Issue: 1
Year: 2010
MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease

Author(s): Michaud Jean-Philippe | Richard Karine | Rivest Serge
Volume: 6
Issue: 1
Year: 2011
Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

Author(s): Wang Jun | Ferruzzi Mario | Varghese Merina | Qian Xianjuan | Cheng Alice | Xie Mathew | Zhao Wei | Ho Lap | Pasinetti Giulio
Volume: 6
Issue: 1
Year: 2011
Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons

Author(s): Lambert Wendi | Ruiz Lupe | Crish Samuel | Wheeler Larry | Calkins David
Volume: 6
Issue: 1
Year: 2011
Protein kinase C and rho activated coiled coil protein kinase 2 (ROCK2) modulate Alzheimer's APP metabolism and phosphorylation of the Vps10-domain protein, SorL1

Author(s): Lane Rachel | Gatson Joshua | Small Scott | Ehrlich Michelle | Gandy Sam
Volume: 5
Issue: 1
Year: 2010
Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

Author(s): Davis Richard | Marsden Ian | Maloney Michael | Minamide Laurie | Podlisny Marcia | Selkoe Dennis | Bamburg James
Volume: 6
Issue: 1
Year: 2011
Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

Author(s): Bellinger Frederick | Bellinger Miyoko | Seale Lucia | Takemoto Andrea | Raman Arjun | Miki Takanori | Manning-Boğ Amy | Berry Marla | White Lon | Ross G
Volume: 6
Issue: 1
Year: 2011
Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Author(s): Woodruff Trent | Thundyil John | Tang Sung-Chun | Sobey Christopher | Taylor Stephen | Arumugam Thiruma
Volume: 6
Issue: 1
Year: 2011
Inhibition of RhoA GTPase and the subsequent activation of PTP1B protects cultured hippocampal neurons against amyloid β toxicity

Author(s): Chacon Pedro | Garcia-Mejias Rosa | Rodriguez-Tebar Alfredo
Volume: 6
Issue: 1
Year: 2011
Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway

Author(s): Guo Huang | Barrett Theresa | Zhong Zhihui | Fernández José | Griffin John | Freeman Robert | Zlokovic Berislav
Volume: 6
Issue: 1
Year: 2011
Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1

Author(s): Chitramuthu Babykumari | Baranowski David | Kay Denis | Bateman Andrew | Bennett Hugh
Volume: 5
Issue: 1
Year: 2010
Aminopeptidases do not directly degrade tau protein

Author(s): Chow K | Guan Hanjun | Hersh Louis
Volume: 5
Issue: 1
Year: 2010
Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-β peptides in the cerebral spinal fluid of rats

Author(s): Suon Sokreine | Zhao Jie | Villarreal Stephanie | Anumula Nikesh | Liu Mali | Carangia Linda | Renger John | Zerbinatti Celina
Volume: 5
Issue: 1
Year: 2010
Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation

Author(s): Caccamo Antonella | Magrí Andrea | Oddo Salvatore
Volume: 5
Issue: 1
Year: 2010
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

Author(s): O'Leary John | Li Qingyou | Marinec Paul | Blair Laura | Congdon Erin | Johnson Amelia | Jinwal Umesh | Koren John | Jones Jeffrey | Kraft Clara | Peters Melinda | Abisambra Jose | Duff Karen | Weeber Edwin | Gestwicki Jason | Dickey Chad
Volume: 5
Issue: 1
Year: 2010
Presenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's disease

Author(s): De Gasperi Rita | Sosa Miguel | Dracheva Stella | Elder Gregory
Volume: 5
Issue: 1
Year: 2010
The biochemical aftermath of anti-amyloid immunotherapy

Author(s): Maarouf Chera | Daugs Ian | Kokjohn Tyler | Kalback Walter | Patton R Lyle | Luehrs Dean | Masliah Eliezer | Nicoll James | Sabbagh Marwan | Beach Thomas | Castaño Eduardo | Roher Alex
Volume: 5
Issue: 1
Year: 2010
Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

Author(s): Vieira Sandra | Rebelo Sandra | Esselmann Hermann | Wiltfang Jens | Lah James | Lane Rachel | Small Scott | Gandy Sam | da Cruz e Silva Edgar | da Cruz e Silva Odete
Volume: 5
Issue: 1
Year: 2010
No dramatic age-related loss of hair cells and spiral ganglion neurons in Bcl-2 over-expression mice or Bax null mice

Author(s): Shen Haiyan | Matsui Jonathan | Lei Debin | Han Lirong | Ohlemiller Kevin | Bao Jianxin
Volume: 5
Issue: 1
Year: 2010
Localization of BDNF mRNA with the Huntington's disease protein in rat brain

Author(s): Ma Bin | Culver Brady | Baj Gabriele | Tongiorgi Enrico | Chao Moses | Tanese Naoko
Volume: 5
Issue: 1
Year: 2010
ApoE mimetic peptide decreases Aβ production in vitro and in vivo

Author(s): Minami S Sakura | Cordova Antoinette | Cirrito John | Tesoriero Joseph | Babus Lenard | Davis Gary | Dakshanamurthy Sivanesan | Turner R Scott | Pak Daniel | Rebeck G William | Paige Mikell | Hoe Hyang-Sook
Volume: 5
Issue: 1
Year: 2010
Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy

Author(s): Fuhrmann Nico | Schimpf Simone | Kamenisch York | Leo-Kottler Beate | Alexander Christiane | Auburger Georg | Zrenner Eberhart | Wissinger Bernd | Alavi Marcel
Volume: 5
Issue: 1
Year: 2010
First evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia

Author(s): Zhou Li | Diefenbach Eve | Crossett Ben | Tran Sieu | Ng Thomas | Rizos Helen | Rua Rejane | Wang Bin | Kapur Amit | Gandhi Kaushal | Brew Bruce | Saksena Nitin
Volume: 5
Issue: 1
Year: 2010
The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

Author(s): Fox Jonathan | Connor Teal | Chopra Vanita | Dorsey Kate | Kama Jibrin | Bleckmann Dorothee | Betschart Claudia | Hoyer Daniel | Frentzel Stefan | DiFiglia Marian | Paganetti Paolo | Hersch Steven
Volume: 5
Issue: 1
Year: 2010
High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function

Author(s): Fallini Claudia | Bassell Gary | Rossoll Wilfried
Volume: 5
Issue: 1
Year: 2010
Phospholipase A2 inhibitors protect against prion and Aβ mediated synapse degeneration

Author(s): Bate Clive | Tayebi Mourad | Williams Alun
Volume: 5
Issue: 1
Year: 2010
Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease

Author(s): Schneider Lonnie | Zhang Jianhua
Volume: 5
Issue: 1
Year: 2010
Tetrabenazine is neuroprotective in Huntington's disease mice

Author(s): Wang Hongyu | Chen Xi | Li Yuemei | Tang Tie-Shan | Bezprozvanny Ilya
Volume: 5
Issue: 1
Year: 2010
Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells

Author(s): Dietrich Hans | Xiang Chuanxi | Han Byung | Zipfel Gregory | Holtzman David
Volume: 5
Issue: 1
Year: 2010
The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein

Author(s): Kim Jihoon | Harada Ryuichi | Kobayashi Masaki | Kobayashi Natsuki | Sode Koji
Volume: 5
Issue: 1
Year: 2010
Effect of Apolipoprotein E ε4 on the association between health behaviors and cognitive function in late midlife

Author(s): Sabia Séverine | Kivimaki Mika | Kumari Meena | Shipley Martin | Singh-Manoux Archana
Volume: 5
Issue: 1
Year: 2010
ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions

Author(s): Keeney Paula | Bennett James
Volume: 5
Issue: 1
Year: 2010
Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease

Author(s): Aboukhatwa Marwa | Dosanjh Laura | Luo Yuan
Volume: 5
Issue: 1
Year: 2010
Distinct cerebrospinal fluid amyloid β peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease

Author(s): Portelius Erik | Andreasson Ulf | Ringman John | Buerger Katharina | Daborg Jonny | Buchhave Peder | Hansson Oskar | Harmsen Andreas | Gustavsson Mikael | Hanse Eric | Galasko Douglas | Hampel Harald | Blennow Kaj | Zetterberg Henrik
Volume: 5
Issue: 1
Year: 2010
Wnt-5a occludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons

Author(s): Cerpa Waldo | Farías Ginny | Godoy Juan | Fuenzalida Marco | Bonansco Christian | Inestrosa Nibaldo
Volume: 5
Issue: 1
Year: 2010
Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease

Author(s): Kajiwara Yuji | Franciosi Sonia | Takahashi Nagahide | Krug Lisa | Schmeidler James | Taddei Kevin | Haroutunian Vahram | Fried Ulrik | Ehrlich Michelle | Martins Ralph | Gandy Samuel | Buxbaum Joseph
Volume: 5
Issue: 1
Year: 2010
Amyloid-β-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Aβ peptide. Implications for the pathogenesis of Alzheimer's disease

Author(s): Dinamarca Margarita | Sagal Juan | Quintanilla Rodrigo | Godoy Juan | Arrázola Macarena | Inestrosa Nibaldo
Volume: 5
Issue: 1
Year: 2010
PrPSc accumulation in neuronal plasma membranes links Notch-1 activation to dendritic degeneration in prion diseases

Author(s): DeArmond Stephen | Bajsarowicz Krystyna
Volume: 5
Issue: 1
Year: 2010
Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons

Author(s): Lazo Oscar | Mauna Jocelyn | Pissani Claudia | Inestrosa Nibaldo | Bronfman Francisca
Volume: 5
Issue: 1
Year: 2010
Dynamic transport and localization of alpha-synuclein in primary hippocampal neurons

Author(s): Yang Mong-Lin | Hasadsri Linda | Woods Wendy | George Julia
Volume: 5
Issue: 1
Year: 2010
Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration

Author(s): Krüger Johanna | Hinttala Reetta | Majamaa Kari | Remes Anne
Volume: 5
Issue: 1
Year: 2010
ZnT3 mRNA levels are reduced in Alzheimer's disease post-mortem brain

Author(s): Beyer Nancy | Coulson David | Heggarty Shirley | Ravid Rivka | Irvine G Brent | Hellemans Jan | Johnston Janet
Volume: 4
Issue: 1
Year: 2009
Effects of chronic low dose rotenone treatment on human microglial cells

Author(s): Shaikh Shamim | Nicholson Louise
Volume: 4
Issue: 1
Year: 2009
Acute dosing of latrepirdine (Dimebon™), a possible Alzheimer therapeutic, elevates extracellular amyloid-β levels in vitro and in vivo

Author(s): Steele John | Kim Soong | Cirrito John | Verges Deborah | Restivo Jessica | Westaway David | Fraser Paul | Hyslop Peter | Sano Mary | Bezprozvanny Ilya | Ehrlich Michelle | Holtzman David | Gandy Sam
Volume: 4
Issue: 1
Year: 2009
The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line

Author(s): Duncan R Scott | Chapman Kent | Koulen Peter
Volume: 4
Issue: 1
Year: 2009
Does neuroinflammation fan the flame in neurodegenerative diseases?

Author(s): Frank-Cannon Tamy | Alto Laura | McAlpine Fiona | Tansey Malú
Volume: 4
Issue: 1
Year: 2009
Development of monoclonal antibodies and quantitative ELISAs targeting insulin-degrading enzyme

Author(s): DelleDonne Anthony | Kouri Naomi | Reinstatler Lael | Sahara Tomoko | Li Lilin | Zhao Ji | Dickson Dennis | Ertekin-Taner Nilufer | Leissring Malcolm
Volume: 4
Issue: 1
Year: 2009
Meeting report: 2009 international conference on molecular neurodegeneration May 18-20, 2009, Xiamen, China

Author(s): Zhang Yunwu | Owens Lisa | Bu Guojun
Volume: 4
Issue: 1
Year: 2009
Dietary composition modulates brain mass and solubilizable Aβ levels in a mouse model of aggressive Alzheimer's amyloid pathology

Author(s): Pedrini Steve | Thomas Carlos | Brautigam Hannah | Schmeidler James | Ho Lap | Fraser Paul | Westaway David | Hyslop Peter | Martins Ralph | Buxbaum Joseph | Pasinetti Giulio | Dickstein Dara | Hof Patrick | Ehrlich Michelle | Gandy Sam
Volume: 4
Issue: 1
Year: 2009
Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

Author(s): Grear Karrie | Ling I-Fang | Simpson James | Furman Jennifer | Simmons Christopher | Peterson Shawn | Schmitt Frederick | Markesbery William | Liu Qiang | Crook Julia | Younkin Steven | Bu Guojun | Estus Steven
Volume: 4
Issue: 1
Year: 2009
Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

Author(s): Montag Judith | Hitt Reiner | Opitz Lennart | Schulz-Schaeffer Walter | Hunsmann Gerhard | Motzkus Dirk
Volume: 4
Issue: 1
Year: 2009
What have worm models told us about the mechanisms of neuronal dysfunction in human neurodegenerative diseases?

Author(s): Teschendorf Dawn | Link Christopher
Volume: 4
Issue: 1
Year: 2009
Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis

Author(s): Tovar-y-Romo Luis | Santa-Cruz Luz | Tapia Ricardo
Volume: 4
Issue: 1
Year: 2009
Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons

Author(s): Daher João | Ying Mingyao | Banerjee Rebecca | McDonald Rebecca | Hahn Myriam | Yang Lichuan | Flint Beal M | Thomas Bobby | Dawson Valina | Dawson Ted | Moore Darren
Volume: 4
Issue: 1
Year: 2009
Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

Author(s): Yamin Rina | Zhao Cheng | O'Connor Peter | McKee Ann | Abraham Carmela
Volume: 4
Issue: 1
Year: 2009
Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy

Author(s): Trimmer Patricia | Schwartz Kathleen | Borland M Kathleen | De Taboada Luis | Streeter Jackson | Oron Uri
Volume: 4
Issue: 1
Year: 2009
GSK-3β phosphorylation of functionally distinct tau isoforms has differential, but mild effects

Author(s): Voss Kellen | Gamblin T Chris
Volume: 4
Issue: 1
Year: 2009
Existing plaques and neuritic abnormalities in APP:PS1 mice are not affected by administration of the gamma-secretase inhibitor LY-411575

Author(s): Garcia-Alloza Monica | Subramanian Meenakshi | Thyssen Diana | Borrelli Laura | Fauq Abdul | Das Pritam | Golde Todd | Hyman Bradley | Bacskai Brian
Volume: 4
Issue: 1
Year: 2009
Calcium signaling in neurodegeneration

Author(s): Marambaud Philippe | Dreses-Werringloer Ute | Vingtdeux Valérie
Volume: 4
Issue: 1
Year: 2009
Calnuc plays a role in dynamic distribution of Gαi but not Gβ subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells

Author(s): Lin Ping | Fischer Thierry | Lavoie Christine | Huang Haining | Farquhar Marilyn
Volume: 4
Issue: 1
Year: 2009
The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events

Author(s): Bhaskar Kiran | Miller Megan | Chludzinski Alexandra | Herrup Karl | Zagorski Michael | Lamb Bruce
Volume: 4
Issue: 1
Year: 2009
The role of tau in neurodegeneration

Author(s): Gendron Tania | Petrucelli Leonard
Volume: 4
Issue: 1
Year: 2009
Independent component analysis of Alzheimer's DNA microarray gene expression data

Author(s): Kong Wei | Mou Xiaoyang | Liu Qingzhong | Chen Zhongxue | Vanderburg Charles | Rogers Jack | Huang Xudong
Volume: 4
Issue: 1
Year: 2009
Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Aβ and insulin degradation

Author(s): Bulloj Ayelén | Leal María | Surace Ezequiel | Zhang Xue | Xu Huaxi | Ledesma Maria | Castaño Eduardo | Morelli Laura
Volume: 3
Issue: 1
Year: 2008
Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains

Author(s): Baulac Stéphanie | Lu Hope | Strahle Jennifer | Yang Ting | Goldberg Matthew | Shen Jie | Schlossmacher Michael | Lemere Cynthia | Lu Qun | Xia Weiming
Volume: 4
Issue: 1
Year: 2009
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on β-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells

Author(s): Prasanthi Jaya | Huls Amber | Thomasson Sarah | Thompson Alex | Schommer Eric | Ghribi Othman
Volume: 4
Issue: 1
Year: 2009
Inducible mutant huntingtin expression in HN10 cells reproduces Huntington's disease-like neuronal dysfunction

Author(s): Weiss Andreas | Roscic Ana | Paganetti Paolo
Volume: 4
Issue: 1
Year: 2009
Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells

Author(s): Borland M Kathleen | Trimmer Patricia | Rubinstein Jeremy | Keeney Paula | Mohanakumar KP | Liu Lei | Bennett James
Volume: 3
Issue: 1
Year: 2008
Insulin-degrading enzyme is exported via an unconventional protein secretion pathway

Author(s): Zhao Ji | Li Lilin | Leissring Malcolm
Volume: 4
Issue: 1
Year: 2009
Intracellular amyloid formation in muscle cells of Aβ-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification

Author(s): Minniti Alicia | Rebolledo Daniela | Grez Paula | Fadic Ricardo | Aldunate Rebeca | Volitakis Irene | Cherny Robert | Opazo Carlos | Masters Colin | Bush Ashley | Inestrosa Nibaldo
Volume: 4
Issue: 1
Year: 2009
The gene coding for PGC-1α modifies age at onset in Huntington's Disease

Author(s): Weydt Patrick | Soyal Selma | Gellera Cinzia | DiDonato Stefano | Weidinger Claus | Oberkofler Hannes | Landwehrmeyer G Bernhard | Patsch Wolfgang
Volume: 4
Issue: 1
Year: 2009
Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

Author(s): Maarouf Chera | Daugs Ian | Spina Salvatore | Vidal Ruben | Kokjohn Tyler | Patton R Lyle | Kalback Walter | Luehrs Dean | Walker Douglas | Castaño Eduardo | Beach Thomas | Ghetti Bernardino | Roher Alex
Volume: 3
Issue: 1
Year: 2008
Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin

Author(s): Shin Thuzar | Isas J Mario | Hsieh Chia-Ling | Kayed Rakez | Glabe Charles | Langen Ralf | Chen Jeannie
Volume: 3
Issue: 1
Year: 2008
Evaluation of Dimebon in cellular model of Huntington's disease

Author(s): Wu Jun | Li Qin | Bezprozvanny Ilya
Volume: 3
Issue: 1
Year: 2008
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease

Author(s): Bryan Kathryn | Zhu Xiongwei | Harris Peggy | Perry George | Castellani Rudy | Smith Mark | Casadesus Gemma
Volume: 3
Issue: 1
Year: 2008
Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role

Author(s): Giliberto Luca | Zhou Dawang | Weldon Richard | Tamagno Elena | De Luca Pasquale | Tabaton Massimo | D'Adamio Luciano
Volume: 3
Issue: 1
Year: 2008
Prion protein lacks robust cytoprotective activity in cultured cells

Author(s): Christensen Heather | Harris David
Volume: 3
Issue: 1
Year: 2008
A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport

Author(s): Wang Lina | Brown Anthony
Volume: 5
Issue: 1
Year: 2010
Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

Author(s): Scales Timothy | Derkinderen Pascal | Leung Kit-Yi | Byers Helen | Ward Malcolm | Price Caroline | Bird Ian | Perera Timothy | Kellie Stuart | Williamson Ritchie | Anderton Brian | Reynolds C Hugh
Volume: 6
Issue: 1
Year: 2011
Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model

Author(s): Wang Xu | Zheng Wei | Xie Jing-Wei | Wang Tao | Wang Si-Ling | Teng Wei-Ping | Wang Zhan-You
Volume: 5
Issue: 1
Year: 2010
BACE1 gene variants do not influence BACE1 activity, levels of APP or Aβ isoforms in CSF in Alzheimer's disease

Author(s): Sjölander Annica | Zetterberg Henrik | Andreasson Ulf | Minthon Lennart | Blennow Kaj
Volume: 5
Issue: 1
Year: 2010
Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?

Author(s): Akram Afia | Schmeidler James | Katsel Pavel | Hof Patrick | Haroutunian Vahram
Volume: 5
Issue: 1
Year: 2010
Endocytic pathways mediating oligomeric Aβ42 neurotoxicity

Author(s): Yu Chunjiang | Nwabuisi-Heath Evelyn | Laxton Kevin | LaDu Mary
Volume: 5
Issue: 1
Year: 2010
Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's disease

Author(s): Zetterberg Madeleine | Sjölander Annica | von Otter Malin | Palmér Mona | Landgren Sara | Minthon Lennart | Wallin Anders | Andreasen Niels | Blennow Kaj | Zetterberg Henrik
Volume: 5
Issue: 1
Year: 2010
GSK3 and p53 - is there a link in Alzheimer's disease?

Author(s): Proctor Carole | Gray Douglas
Volume: 5
Issue: 1
Year: 2010
Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF

Author(s): Choi Se | Li Yun | Parada Luis | Sisodia Sangram
Volume: 4
Issue: 1
Year: 2009
Alzheimer's disease: synaptic dysfunction and Aβ

Author(s): Shankar Ganesh | Walsh Dominic
Volume: 4
Issue: 1
Year: 2009
Neuroprotective effects of blockers for T-type calcium channels

Author(s): Wildburger Norelle | Lin-Ye Avary | Baird Michelle | Lei Debin | Bao Jianxin
Volume: 4
Issue: 1
Year: 2009
Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients

Author(s): Zhong Zhenyu | Nural Hikmet | He Ping | Civarella Gina | Beach Thomas | Sue Lucia | Adler Charles | Shill Holly | Caviness John | Xia Weiming | Shen Yong
Volume: 4
Issue: 1
Year: 2009
Emerging role of LRRK2 in human neural progenitor cell cycle progression, survival and differentiation

Author(s): Milosevic Javorina | Schwarz Sigrid | Ogunlade Vera | Meyer Anne | Storch Alexander | Schwarz Johannes
Volume: 4
Issue: 1
Year: 2009
Dissembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients

Author(s): Nural Hikmet | He Ping | Beach Thomas | Sue Lucia | Xia Weiming | Shen Yong
Volume: 4
Issue: 1
Year: 2009
All-you-can-eat: autophagy in neurodegeneration and neuroprotection

Author(s): Jaeger Philipp | Wyss-Coray Tony
Volume: 4
Issue: 1
Year: 2009
α-Synuclein and neuronal cell death

Author(s): Cookson Mark
Volume: 4
Issue: 1
Year: 2009
PGC-1alpha as modifier of onset age in Huntington disease

Author(s): Taherzadeh-Fard Elahe | Saft Carsten | Andrich Jürgen | Wieczorek Stefan | Arning Larissa
Volume: 4
Issue: 1
Year: 2009
The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease

Author(s): Inestrosa Nibaldo | Toledo Enrique
Volume: 3
Issue: 1
Year: 2008
Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice

Author(s): Mirnics Károly | Norstrom Eric | Garbett Krassimira | Choi Se | Zhang Xiaoqiong | Ebert Philip | Sisodia Sangram
Volume: 3
Issue: 1
Year: 2008
Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment

Author(s): Lefterov Iliya | Bookout Angie | Wang Zhu | Staufenbiel Matthias | Mangelsdorf David | Koldamova Radosveta
Volume: 2
Issue: 1
Year: 2007
The Alzheimer's disease β-secretase enzyme, BACE1

Author(s): Cole Sarah | Vassar Robert
Volume: 2
Issue: 1
Year: 2007
From a Parkinson's disease expert: Rasagiline and the Future of Therapy

Author(s): Lakhan Shaheen
Volume: 2
Issue: 1
Year: 2007
Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice

Author(s): Yamaguchi Hiroo | Shen Jie
Volume: 2
Issue: 1
Year: 2007
Lack of α-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease

Author(s): Kallhoff Verena | Peethumnongsin Erica | Zheng Hui
Volume: 2
Issue: 1
Year: 2007
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease

Author(s): Casadesus Gemma | Smith Mark | Basu Samar | Hua Jing | Capobianco Dae | Siedlak Sandra | Zhu Xiongwei | Perry George
Volume: 2
Issue: 1
Year: 2007
Multiple pathways contribute to the pathogenesis of Huntington disease

Author(s): Li Shihua | Li Xiao-Jiang
Volume: 1
Issue: 1
Year: 2006
MicroRNAs can regulate human APP levels

Author(s): Patel Neha | Hoang David | Miller Nathan | Ansaloni Sara | Huang Qihong | Rogers Jack | Lee Jeremy | Saunders Aleister
Volume: 3
Issue: 1
Year: 2008
Tau exon 10 alternative splicing and tauopathies

Author(s): Liu Fei | Gong Cheng-Xin
Volume: 3
Issue: 1
Year: 2008
Dopaminergic regeneration by neurturin-overexpressing c17.2 neural stem cells in a rat model of Parkinson's disease

Author(s): Liu Wei-Guo | Wang Xi-Jing | Lu Guo-Qiang | Li Biao | Wang Gang | Chen Sheng-Di
Volume: 2
Issue: 1
Year: 2007
APP-BP1 inhibits Aβ42 levels by interacting with Presenilin-1

Author(s): Chen Yuzhi | Bodles Angela | McPhie Donna | Neve Rachael | Mrak Robert | Griffin W Sue
Volume: 2
Issue: 1
Year: 2007
T cell mediated cerebral hemorrhages and microhemorrhages during passive Aβ immunization in APPPS1 transgenic mice

Author(s): Meyer-Luehmann Melanie | Mora J Rodrigo | Mielke Matthew | Spires-Jones Tara | de Calignon Alix | von Andrian Ulrich | Hyman Bradley
Volume: 6
Issue: 1
Year: 2011
Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy

Author(s): Barbeito Ana | Levade Thierry | Delisle Marie | Ghetti Bernardino | Vidal Ruben
Volume: 5
Issue: 1
Year: 2010
6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death

Author(s): Bernstein Alison | Garrison Sean | Zambetti Gerard | O'Malley Karen
Volume: 6
Issue: 1
Year: 2011
Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD)

Author(s): Salemi Jon | Obregon Demian | Cobb Anthony | Reed Spenser | Sadic Edin | Jin Jingji | Fernandez Francisco | Tan Jun | Giunta Brian
Volume: 6
Issue: 1
Year: 2011
Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease?

Author(s): Greggio Elisa | Bisaglia Marco | Civiero Laura | Bubacco Luigi
Volume: 6
Issue: 1
Year: 2011
Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation

Author(s): Uemura Kengo | Farner Katherine | Nasser-Ghodsi Navine | Jones Phill | Berezovska Oksana
Volume: 6
Issue: 1
Year: 2011
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model

Author(s): Khandelwal Preeti | Dumanis Sonya | Feng Li | Maguire-Zeiss Kathleen | Rebeck GW | Lashuel Hilal | Moussa Charbel
Volume: 5
Issue: 1
Year: 2010
Heat shock protein 90 in neurodegenerative diseases

Author(s): Luo Wenjie | Sun Weilin | Taldone Tony | Rodina Anna | Chiosis Gabriela
Volume: 5
Issue: 1
Year: 2010
Microglia in the aging brain: relevance to neurodegeneration

Author(s): Luo Xiao-Guang | Ding Jian-Qing | Chen Sheng-Di
Volume: 5
Issue: 1
Year: 2010
Novel cerebrovascular pathology in mice fed a high cholesterol diet

Author(s): Franciosi Sonia | Gama Sosa Miguel | English Daniel | Oler Elizabeth | Oung Twethida | Janssen William | De Gasperi Rita | Schmeidler James | Dickstein Dara | Schmitz Christoph | Gandy Sam | Hof Patrick | Buxbaum Joseph | Elder Gregory
Volume: 4
Issue: 1
Year: 2009
Apolipoprotein E4 (1–272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells

Author(s): Nakamura Toshiyuki | Watanabe Atsushi | Fujino Takahiro | Hosono Takashi | Michikawa Makoto
Volume: 4
Issue: 1
Year: 2009
Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

Author(s): Su Bo | Liu Haihua | Wang Xinglong | Chen Shu | Siedlak Sandra | Kondo Eisaku | Choi Raymond | Takeda Atsushi | Castellani Rudy | Perry George | Smith Mark | Zhu Xiongwei | Lee Hyoung-gon
Volume: 4
Issue: 1
Year: 2009
The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

Author(s): Tamayev Robert | Zhou Dawang | D'Adamio Luciano
Volume: 4
Issue: 1
Year: 2009
ApoE isoform-dependent changes in hippocampal synaptic function

Author(s): Korwek Kimberly | Trotter Justin | LaDu Mary | Sullivan Patrick | Weeber Edwin
Volume: 4
Issue: 1
Year: 2009
An exo-cell assay for examining real-time γ-secretase activity and inhibition

Author(s): Shelton Christopher | Tian Yuan | Frattini Mark | Li Yue-Ming
Volume: 4
Issue: 1
Year: 2009
LRP1 shedding in human brain: roles of ADAM10 and ADAM17

Author(s): Liu Qiang | Zhang Juan | Tran Hien | Verbeek Marcel | Reiss Karina | Estus Steven | Bu Guojun
Volume: 4
Issue: 1
Year: 2009
In vivo silencing of alpha-synuclein using naked siRNA

Author(s): Lewis Jada | Melrose Heather | Bumcrot David | Hope Andrew | Zehr Cynthia | Lincoln Sarah | Braithwaite Adam | He Zhen | Ogholikhan Sina | Hinkle Kelly | Kent Caroline | Toudjarska Ivanka | Charisse Klaus | Braich Ravi | Pandey Rajendra | Heckman Michael | Maraganore Demetrius | Crook Julia | Farrer Matthew
Volume: 3
Issue: 1
Year: 2008
Retraction: Dopaminergic regeneration by neurturin-overexpressing c17.2 neural stem cells in a rat model of Parkinson's disease

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