Author(s): Helmut Spreitzer | Christiane Puschmann
Journal: Molbank
ISSN 1422-8599
Volume: 2012;
Issue: 4;
Start page: M781;
Date: 2012;
Original page
Keywords: pyrrole | DNA-alkylation | anticancer
ABSTRACT
An aziridine-containing side chain is attached to an oxonaphthalene-annelated pyrrole in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.
Journal: Molbank
ISSN 1422-8599
Volume: 2012;
Issue: 4;
Start page: M781;
Date: 2012;
Original page
Keywords: pyrrole | DNA-alkylation | anticancer
ABSTRACT
An aziridine-containing side chain is attached to an oxonaphthalene-annelated pyrrole in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.