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The activities of endothelial elastase and cathepsin G in rats at oxidative stress caused by heavy metals salts

Author(s): Nickolaj F. Starodub | Ljubov M. Samokhina

Journal: Advances in Biological Chemistry
ISSN 2162-2183

Volume: 03;
Issue: 02;
Start page: 208;
Date: 2013;
Original page

Keywords: Endothelial Elastase | Cathepsin G | Cobalt Chloride | Mercury Chloride | Rats

stase (EEl) in kidney that indicated the development of destructive processes. CoCl2 introduction decreased EEl and cathepsin G activities in blood serum and cathepsin G in lungs. HgCl2 injection decreased EEl in blood serum, heart, liver, kidney and cathepsin G in blood serum. These decreasing of proteinases activities may be caused by cytotoxic effects of heavy metals and/or the inclusion of these proteases in the destructive processes and absence of their synthesis and/or release.
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