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ACUTE PHASE PROTEIN RESPONSES IN MICE INFECTED WITH RIVER WATER CONTAMINATED BY PASTEURELLA MULTOCIDA TYPE B: 2

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Author(s): Mohammed Muqdad Khaleel | Faez Firdaus Jesse Abdullah | Lawan Adamu | Abdinasir Yusuf Osman | Abdul Wahid Haron | Mohd Zamri Saad | Abdul Rahman Omar

Journal: American Journal of Animal and Veterinary Sciences
ISSN 1557-4555

Volume: 8;
Issue: 3;
Start page: 159;
Date: 2013;
Original page

Keywords: Serum Amyloid A (SAA) | Haptoglobin (Hp) | Pasteurella Multocida type B: 2 | Different Routes | Contaminated River Water | Infected Mice Carcasses

ABSTRACT
Animals are predisposed to infections through varieties of ways which activate the innate immune systems at the initial phase of acute infections. Hemorrhagic Septicemia (HS) is a devastating septicemic disease of cattle and buffaloes caused by a particular serotypes of Pasteurella multocida and serotype B: 2 is the most important cause of the disease in Asia. Therefore, the present study aims to investigate on acute phase protein responses in mice infected with river water contaminated by Pasteurella multocida type B: 2. Five infected mice were placed in each tank containing river water for 24, 48 and 72 h. The groups comprise of five mice each made up of the control, intraperitoneal, oral and the aerosol routes. There were increased concentrations of Haptoglobin (Hp) in the mice inoculated with infected river water kept for 24 h intraperitoneally (p
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