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Agentes Implicados en infección neonatal nosocomial y patrón de sensibilidad

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Author(s): Juan Useche | Elio Núñez | Humberto Torres

Journal: Salus Online
ISSN 1316-7138

Volume: 16;
Issue: 3;
Start page: 49;
Date: 2012;
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Keywords: neonatal nosocomial sepsis | susceptibility | Gram-negative bacteria

ABSTRACT
In order to determine the agents involved in nosocomial infections and their antimicrobialsusceptibility in neonatology patients, a prospective study was carried out on 101bacterial isolates, and cases of nosocomial sepsis were analyzed. We identified the susceptibility of strains by conventional microbiology with universal and selective culture media. Sensitivity was analyzed for estimation of rates for each 100 admissions. The incidence of nosocomial neonatal sepsis was 36.4%. Gram-negative bacteria (Klebsiella pn., Escherichia coli and nonfermenting)were predominant, 54.4%, followed by Gram-positive bacteria (Staphylococcus aureus and coagulasenegative Staphylococcus) 37.6%, and 7.9% fungi. Susceptibility to aminoglycosides was 28%. Sensitivity to ciprofloxacin for Klebsiella was 56.2%. Sensitivity of non-fermenters tocefepime and 3rd generation cephalosporins was 50%. Regarding meropenem, Escherichia coli was 54.4% sensitive, Klebsiella 65.5%, and non-fermenters 50%.Sensitivity of Escherichia coli, Klebsiella and nonfermenters to piperacillin-tazobactam was 45.4%, 40.6% and 50%, zespectively. Sensitivity to colistin was 83.3% for nonfermenters, 71.8% for Klebsiella and 63.6% for Escherichia coli. Sensitivity of Staphylococcus aureus to oxacillin was 18.7%, and 100% to linezolid and vancomycin teicoplamina. Coagulasenegative Staphylococcus was 100% sensitive to linezolid, teicoplanin and vancomycin, and 46.6% to clindamycin. Results show stability of causal agents in the circulation, predominantly gram-negative bacteria and low susceptibility to antimicrobial therapy used.
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