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Analgesic Effects of Intrathecally Administered Fentanyl in Spinal Anaesthesia for Lower Limb Surgery

Author(s): Olanrewaju N. Akanmu | Olaitan A. Soyannwo | Patience T. Sotunmbi | Adesuwa S. Lawani-Osunde | Ibironke Desalu | Oyebola O. Adekola | Sofela E. Oridota

Journal: Macedonian Journal of Medical Sciences
ISSN 1857-5749

Volume: 6;
Issue: 3;
Start page: 255;
Date: 2013;
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Keywords: intrathecal | subarachnoid block | analgesia | fentanyl | complications.

Background: Intrathecal opioids as adjuvants to local anaesthetics during spinal anaesthesia have been used to augment the analgesia produced by local anaesthetic agents. The aim of this study is to determine the duration of analgesia following addition of fentanyl to 0.5% hyperbaric bupivacaine during open reduction of lower limb fractures.Material and Methods: This prospective randomized study is comparing the effect of addition of 25µg of fentanyl to 10 mg of 0.5% hyperbaric bupivacaine intrathecally on sixty consecutive ASA I and II patients scheduled to undergo elective open reduction and internal fixation of lower limb fractures (ORIF) at the UCH, Ibadan. The patients were randomized into their either bupivacaine saline (SB n=30) 10 mg (2 ml) 0.5% hyperbaric bupivacaine or bupivacaine-fentanyl combination (FB n= 30) through a 25-guage Whitacre spinal needle. Quality and duration of analgesia as well as any sequelae were recorded.Result: Socio-demographic as well as operating data were comparable between the two groups. Fentanyl provided significantly longer duration of complete (239.97 ± 28.58 vs 129.17 ± 11.61), p
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