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Analysis of the densitometric method of hand bone radiograms and assessment of early changes of bone structure in the children with Gaucher's disease on enzyme replacement therapy (ERT) --- Analiza radiogramów kości ręki metodą densytometryczną w ocenie wczesnych zmian w strukturze kości u dzieci z choroba Gauchera leczonych enzymatycznie

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Author(s): Anna Tylki-Szymańska | Waldemar Skawiński | Grażyna Łysoń-Wojciechowska

Journal: Pediatric Endocrinology, Diabetes and Metabolism
ISSN 1234-625X

Volume: 13;
Issue: 3;
Start page: 159;
Date: 2007;
Original page

ABSTRACT
In the study of changes of bone structure eighteen children with Gaucher's disease (ERT) at the 4 to 19,8 years, used was densitometric in vivo method of hand bone radiograms. On the basis of the radiogram assessed was the bone age of patient also optical bone density and dimension in the second metacarpal bone. Differential diagnostics was produced based on standarized cortical thickness and optical bone density, according to the norm of Polish population (1989, 2004). The analysis of hand bone radiograms in children with Gaucher's (ERT) showe that 55.5% of patients had normal skeletal status, 38.8% indicated osteopenia traits, one patient had osteoporotic traits.
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