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Analysis of the genetic diversity of arthritis patients with reference to the factors inducing its onset.

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Author(s): Mujapara A.K. | Bushra Jarullah

Journal: International Journal of Genetics
ISSN 0975-2862

Volume: 1;
Issue: 2;
Start page: 06;
Date: 2009;
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Keywords: RAPD | Arthritis | Seronegative

ABSTRACT
A lot of research on the prevalence of arthritis in India population has been carried out. Howeverno studies on the genetic relationships within groups of arthritic patients in India have been reported. Thecurrent study focuses on analyzing the genetic diversity between patients suffering from the various types ofarthritis with reference to factors inducing its onset. A total of 36 patients suffering from different types ofarthritis were analyzed with reference to the age, gender, BMI, family history, hemoglobin and thyroid profile.The variation in the genetic profile was also analyzed using the RAPD technique. Data analysis showedpatients suffering from arthritis to be at a greater risk of thyroid disorders, however the type of arthritisplayed a significant role. A distinct correlation between the genetic variation and presence of arthritisincluding its type was observed.
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