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Antiinflammatory activity of seeds of syzygium cumini linn.

Author(s): D.C. Modi | J.K.Patel | B. N. Shah | B. S. Nayak

Journal: Journal of Pharmaceutical Education and Research
ISSN 0976-8173

Volume: 1;
Issue: 1;
Start page: 68;
Date: 2010;
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Keywords: Anti-inflammatory | Syzygium cumini | Carragennan

Anti-inflammatory activity of the methanolic and aqueous extracts of the seeds of Syzygium cumini Linn was studied in Wistar rats using the carrageenan induced left hind paw edema. The methanolic and aqueous extracts at a dose of 250 mg/kg body wt shows moderate to significant anti-inflammatory activity. The methanolic andaqueous extracts of Syzygium cumini reduced the edema induced by carrageenan by 48.29 % and 68.85 % respectively on oral administration of 250 mg/kg body wt, as compared to the untreated control group. Diclofenac sodium at 100 mg/kg body wt inhibited the edema volume by 75.08 %. The results indicated that the aqueousextract shows more significant anti-inflammatory activity then methanolic extracts when compared with the standard and untreated control.
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