Author(s): S. Kousar | N. Jahan | Khalil-ur-Rehman | S. Nosheen
Journal: Bioscience Research
ISSN 1811-9506
Volume: 8;
Issue: 1;
Start page: 8;
Date: 2011;
Original page
Keywords: Coriandrum Sativum | Coriander | Medicinal plants | Antilipidemic activity
ABSTRACT
Myocardial infraction is a most common cause of death all over the world. The high level of blood cholesterol is a big risk for heart diseases. The basic purpose of this research work was to determine the antilipidemic activity of fresh leaves of coriandrum sativum against salbutamol induced cardiac injury in rabbits. Salbutamol administered rabbits (50mg/kg) showed elevated level of serum lipids (LDL-Cholesterol, Triglyceride) and decreased level of HDL-Cholesterol and antioxidant enzymes (SOD, CAT). Both the pre- and post treatment of plant extract (100mg/kg) for three weeks exert a significant antilipidemic effect against salbutamol-induced myocardial infraction by lowering the level of serum LDL-Cholesterol, Triglycerides and Peroxidase and increasing the level of HDL-Cholesterol and antioxidant enzymes. The results showed that coriandrum sativum possess antilipidemic activity.
Journal: Bioscience Research
ISSN 1811-9506
Volume: 8;
Issue: 1;
Start page: 8;
Date: 2011;
Original page
Keywords: Coriandrum Sativum | Coriander | Medicinal plants | Antilipidemic activity
ABSTRACT
Myocardial infraction is a most common cause of death all over the world. The high level of blood cholesterol is a big risk for heart diseases. The basic purpose of this research work was to determine the antilipidemic activity of fresh leaves of coriandrum sativum against salbutamol induced cardiac injury in rabbits. Salbutamol administered rabbits (50mg/kg) showed elevated level of serum lipids (LDL-Cholesterol, Triglyceride) and decreased level of HDL-Cholesterol and antioxidant enzymes (SOD, CAT). Both the pre- and post treatment of plant extract (100mg/kg) for three weeks exert a significant antilipidemic effect against salbutamol-induced myocardial infraction by lowering the level of serum LDL-Cholesterol, Triglycerides and Peroxidase and increasing the level of HDL-Cholesterol and antioxidant enzymes. The results showed that coriandrum sativum possess antilipidemic activity.
