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Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications

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Author(s): Danny Jian Hang Tng | Rui Hu | Peiyi Song | Indrajit Roy | Ken-Tye Yong

Journal: Micromachines
ISSN 2072-666X

Volume: 3;
Issue: 4;
Start page: 615;
Date: 2012;
Original page

Keywords: MEMS device | drug delivery | biomedical applications | implantable

ABSTRACT
Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their unique properties, microelectromechanical systems (MEMS) technology has been recently engineered as implantable drug delivery systems for disease therapy. This review examines the challenges faced in implementing implantable MEMS drug delivery systems in vivo and the solutions available to overcome these challenges.
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