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Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

Author(s): Marko Kreft | Lasse K Bak | Helle S Waagepetersen | Arne Schousboe

Journal: ASN Neuro
ISSN 1759-0914

Volume: 4;
Issue: 3;
Start page: e00086;
Date: 2012;
Original page

Keywords: amino acid | astrocyte | compartmentation | energy | metabolism

Astrocytes are key players in brain function; they are intimately involved in neuronal signalling processes and their metabolism is tightly coupled to that of neurons. In the present review, we will be concerned with a discussion of aspects of astrocyte metabolism, including energy-generating pathways and amino acid homoeostasis. A discussion of the impact that uptake of neurotransmitter glutamate may have on these pathways is included along with a section on metabolic compartmentation.
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