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Bacteriophages in Escherichia coli antimicrobial resistance

Author(s): Archana Iyer | Elie Barbour | Esam Azhar | Ishtiaq Qadri | Adeel Chaudhary | Adel Abuzenadah | Taha Kumosani | Ghazi Damanhouri | Suhad Bahijri | Ahmed Al-Hejin | Afif M. Abdel Nour | Steve Harakeh

Journal: Advances in Bioscience and Biotechnology
ISSN 2156-8456

Volume: 04;
Issue: 03;
Start page: 469;
Date: 2013;
Original page

Keywords: Bacteriophages | Escherischia coli | Antimicrobial Resistance

The continuous battle between humans and the multitude of pathogenic microorganisms in the environment has sought relief in the form of antimicrobials. But the counter attack by pathogenic organisms in the form of multidrug resistance, acquired by various mechanisms such as transformation, transposition, conjugation and transduction is a major reason for concern. Bacteriophages have contributed in a significant way to dissemination of genes encoding antimicrobial resistance, heavy metal resistance and virulence factors through the phenomenon of transduction. This review aims at compiling information about the different mechanisms by which bacteriophages aid in transferring genes involved in antimicrobial resistance to Escherischia coli in various environments.
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