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Biological Investigations of Dried Fruit of Solanum nigrum Linn.

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Author(s): Utpal Kumar Karmakar | Uttam Kumar Tarafder | Samir Kumar Sadhu | Nripendra Nath Biswas | Manik Chandra Shill

Journal: Stamford Journal of Pharmaceutical Sciences
ISSN 1999-7108

Volume: 3;
Issue: 1;
Start page: 38;
Date: 2010;
Original page

Keywords: Solanum nigrum Linn | analgesic activity | antidiarrheal activity | antimicrobial activity | antioxidant activity | cytotoxic activity.

ABSTRACT
The ethanolic extract of the dried fruit of Solanum nigrum Linn. (Family: Solanaceae) was assessed for its possible analgesic, antidiarrhoeal, antimicrobial, antioxidant and cytotoxic activity. Phytochemical screening of the ethanolic extract revealed the presence of carbohydrate, alkaloids, tannins, saponins, steroids, glycosides, and gums. In acetic acid induced writhing in mice, the ethanolic extract (250 and 500mg/kg) exhibited significant (p
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