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Cardiac diseases and metabolic syndrome in HIV infection

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Author(s): Olusegun Adesola Busari | Olusogo Ebenezer Busari

Journal: Arsiv Kaynak Tarama Dergisi
ISSN 1300-3755

Volume: 22;
Issue: 3;
Start page: 377;
Date: 2013;
Original page

Keywords: Cardiovascular diseases | metabolic syndrome | HIV infection | HAART

ABSTRACT
HIV infection remains a pandemic and a leading cause of morbidity and mortality particularly in sub Sahara Africa. Although highly active antiretroviral therapy has brought about a marked reduction in morbidity and mortality, there are growing concerns on increasing non-communicable complications particularly cardiovascular and metabolic diseases in HIV disease. The objective was to do a systematic review of the clinical entities and pathogenesis of cardiovascular diseases and metabolic syndrome in HIV disease. The result shows that HIV infection and the resultant chronic immune activation; HAAR; opportunistic infections and some of the drugs use for them; and traditional cardiovascular risk factors are some of the conditions associated with cardiovascular diseases and metabolic syndrome in HIV infection. Standard cardiovascular disease screening and risk-reducing interventions should be routinely undertaken for HIV-infected persons. [Archives Medical Review Journal 2013; 22(3.000): 377-392]
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