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Cervical Neoplasia-Cyto-Histological Correlation (Bethesda System) A Study of 276 Cases

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Author(s): Vaishali Jain | AS Vyas

Journal: Journal of Cytology & Histology
ISSN 2157-7099

Volume: 01;
Issue: 02;
Start page: 001;
Date: 2010;
Original page

Keywords: Cervical cytology | Histology | Correlation

ABSTRACT
Carcinoma uterine cervix is one of the leading causes of cancer death among women worldwide. To detect this widely prevalent cancer at an early stage, the simplest test has been a pap smear. Reporting of pap smears is done by using The Bethesda System 2001 prior to which many classification systems were developed [1,2,3,4]. To check the sensitivity and specificity of Bethesda system, the cytological findings have to be correlated with histology considering histopathology as gold standard. In our study, we have correlated cytological findings (pap smears) with corresponding histology after follow up of the symptomatic patients in the age range of 20 to 80 years. The main objectives were to study usefulness of cytology in detecting various preneoplastic and neoplastic lesions of cervix, to evaluate and to interpret the cases of epithelial lesions according to The Bethesda 2001 classification system [5] and correlation of cytological findings with follow-up histology sections. Analysis of different factors causing discrepancies was done.Aims: The study was conducted to study usefulness of cervical cytology by PAP smear and the application of the Bethesda 2001 system in classifying different preneoplastic and neoplastic lesions of cervix.Setting and design: With the use of PAP test and applying the BETHESDA 2001 classification 5, in the present study we have examined cervical smears of symptomatic patients in the age group ranging from 25 to 70 years. Inflammatory & unsatisfactory smears were excluded. The remaining cases showing epithelial abnormalities were followed up and biopsy slides were studied. Cytohistological correlation was done in those cases and results were obtained.
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