Academic Journals Database
Disseminating quality controlled scientific knowledge

CHANGE IN BLOOD GELSOLIN CONCENTRATION IN RESPONSE TO PHYSICAL EXERCISE

ADD TO MY LIST
 
Author(s): Chih-Chieh Yu | Małgorzata Żendzian-Piotrowska | Małgorzata Charmas | Barbara Długołęcka | Marcin Baranowski | Jan Górski | Robert Bucki

Journal: Biology of Sport
ISSN 0860-021X

Volume: 30;
Issue: 3;
Start page: 169;
Date: 2013;
Original page

Keywords: Blood | Exercise | Gelsolin

ABSTRACT
Plasma gelsolin (pGSN) produced by muscle is an abundant protein of extracellular fluids capable of severing actin filaments and eliminating actin from the circulation. Additionally, pGSN modulates the cellular effects of some bioactive lipids. In this study we test the hypothesis that hormonal and metabolic adaptations to exercise are associated with changes in gelsolin concentration in blood. Plasma samples were collected from twenty healthy males recruited from untrained (UT, n=10) and endurance trained (ET, n=10) groups that performed 30-60 minutes of exercise on a cycloergometer at a workload corresponding to 700of VO2max. Gelsolin concentration was determined by quantitative Western blot analysis with an anti-human gelsolin antibody. The gelsolin concentration in UT and ET subjects before starting exercise ranged from 104 to 330 and 163 to 337 µg•ml-1 respectively. After 30 minutes of exercise we observed a significant decrease of plasma gelsolin in the UT group (p
RPA Switzerland

RPA Switzerland

Robotic process automation

    

Tango Jona
Tangokurs Rapperswil-Jona