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Change in quality of life after medical and surgical treatment of graves′ ophthalmopathy

Author(s): Kashkouli Mohsen | Heidari Iraj | Pakdel Farzad | Jam Sara | Honarbakhsh Yasamin | Mirarmandehi Bahareh

Journal: Middle East African Journal of Ophthalmology
ISSN 0974-9233

Volume: 18;
Issue: 1;
Start page: 42;
Date: 2011;
Original page

Keywords: Eyelid Retraction | Graves′ Ophthalmopathy | Proptosis | Quality of Life

Purpose : To assess the changes in quality of life (QOL) of patients after treatment of their Graves′ ophthalmopathy (GO). Materials and Methods : In this prospective, cross-sectional study, the GO-QOL questionnaire was completed by 67 subjects before and at least 6 months after steroid treatment (61 subjects, group 1) or optic neuropathy orbital decompression (6 subjects, group 2). Visual, psychosocial, education and counseling scores (higher score = better health), GO severity and clinical activity scores and minimal clinically important difference (MCID) were recorded and analyzed for correlation and statistical significance. A P-value 0.05). There was no significant effect of duration of thyroid disease and GO and severity and activity of GO on QOL scores either before or after treatment (P > 0.05, all cases). Conclusion : Steroid treatment and orbital decompression significantly improve the QOL in GO. Duration, severity and activity of GO did not have a significant impact on the QOL.
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