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Clinical aspects and laboratory tests of Kawasaki Disease in Iran

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Author(s): Mohammad Bagher Rahmati | Keramat Allah Jahanshahi | Zahra Jahangiri | Hamidreza Mahboobi | Tahereh Khorgoei

Journal: Electronic Physician
ISSN 2008-5842

Volume: 4;
Issue: 1;
Start page: 461;
Date: 2012;
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Keywords: Kawasaki Disease | Clinical Aspects | Laboratory Tests

ABSTRACT
Background: Kawasaki Disease (KD) is a self-limiting vasculitis and is the main cause of acquired cardiac diseasein childhood in developed countries. Early diagnosis and treatment of KD is necessary for prevention of cardiaccomplications in adolescence. The aim of the present study is to assess clinical aspects and laboratory tests in KD inIran.Methods: The study, undertaken in 2009, included all patients admitted to Kudakan hospital in Bandarabbas with adiagnosis of KD during 1997 to 2008. Forty-two children were included in this study. Seven patients were excludedbecause of incomplete records. All eligible patients’ records were reviewed and data including age, sex, clinicalfindings, and laboratory test results were summarized in a structured checklist. Data were analyzed using SPSS 13.0for Windows (SPSS Inc., Chicago, Illinois, USA) software.Results: Among the 35 patients studied, seven (20%) were female, and 28 (80%) were male. Mean age of thepatients was 3.35±2.4. Fever was seen in 35(100%) patients, noninfectious bilateral conjunctivitis in 16(45.71%),noninfectious unilateral conjunctivitis in two (5.7%), lip color change in 18(51.4%), involvement of oropharynx in19(54.3%), strawberry tongue in 11(31.4%), maculopapular rash in 18(51.4%), and erythmatous skin in six (17.1%).Ten patients had an erythrocyte sediment rate (ESR) less than 30.Conclusion: Prevalence of clinical findings in Iran is variable among different areas. Thus KD should be consideredin all children with fever lasting five days or longer to prevent cardiac complications in future.
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