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Clinical updates on diagnosing glutensensitive enteropathy

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Author(s): Faruk Hadziselimovic | Annemarie Bürgin-Wolff

Journal: Acta Medica Academica
ISSN 1840-1848

Volume: 40;
Issue: 2;
Start page: 105;
Date: 2011;
Original page

Keywords: Coeliac disease | Antibodies | Intestinal biopsy | Diagnosis

ABSTRACT
In the last twenty years serology for the diagnosis of coeliac disease has improved substantially. As the result of our serological studies in 1998 we proposed a gentle, low-risk, and cost effective algorithm for diagnosing various forms of gluten sensitive enteropathy, using a combination of different antibody determinations, namely IgA Endomysium antibodies (EMA), Tissue-transglutaminase antibodies (IgA anti tTG, IgG anti tTG), IgA-and IgG antigliadin-antibodies. Performing routinely serologic testing contributes to a decreased rate of endoscopic interventions and improves the quality of the patient’s life.
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