Academic Journals Database
Disseminating quality controlled scientific knowledge

A clinicopathologic study of excised conjunctival lesions

Author(s): Mohamad Elshazly Laila

Journal: Middle East African Journal of Ophthalmology
ISSN 0974-9233

Volume: 18;
Issue: 1;
Start page: 48;
Date: 2011;
Original page

Keywords: Conjunctiva | Hemangioma | Nevus | Ocular Surface Squamous Neoplasia | Papilloma

Purpose : This study was aimed at to determine the frequency of excised conjunctival lesions in a patient population treated over a 10-year period. Materials and Methods : The data of all excised conjunctival lesions with tissue diagnoses from 1998 to 2008 in the pathology department were analyzed. Results : The patient group comprised 192 conjunctival specimens; 106 (55.2%) obtained from male patients and 86 (44.8 %) from female patients. The age range was 75 years with a mean age of 27.07 ± 17 years. The most frequent excised lesions were pyogenic granulomas, which represented 30.7% (59 cases). Pigmented epithelial tumors were the second most common benign conjunctival lesions (44 cases, 22.9%). Out of these cases, compound nevus represented 86.4% (38 cases) and junctional nevus represented 6.8% (3 cases). Primary acquired melanosis and subepithelial nevus were reported in two cases (4.5%) and one case (2.3%), respectively. Cystic lesions represented 12% (23 cases). These were mostly ductal retention cysts in 16 cases (70%), occupying the fornix in eight cases. Ocular surface squamous neoplasia (OSSN) was detected in 21 cases (10.9%) significantly affecting an older age group as compared to other lesions (mean age 45.9 ± 16.7). Other less frequent lesions included papilloma (10 cases, 2.5%), dermolipoma (8 cases, 4.2%), solid dermoid (3 cases, 1.6%), hemangioma (15 cases, 7.8%), and benign reactive lymphoid hyperplasia (four cases, 2.1%). Conclusion : Benign lesions were the most frequent histologically diagnosed conjunctival lesions. The true malignant lesions were lower than what has been described in many reports. The significant proportion of precancerous OSSN can be attributed to sun exposure and ultraviolet light in Egypt.
RPA Switzerland

RPA Switzerland

Robotic process automation


Tango Jona
Tangokurs Rapperswil-Jona