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Comparative Characteristics of Erythrocytes Charge Balance in Patients with Chronic Obstructive Pulmonary Disease

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Author(s): Larissa E. Muravlyova | Vilen B. Molotov-Luchanskiy | Dmitriy A. Klyuyev | Evgeniya A. Kolesnikova

Journal: European Researcher
ISSN 2219-8229

Volume: 58;
Issue: 9-1;
Start page: 2263;
Date: 2013;
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Keywords: chronic obstructive pulmonary disease | charge balance | erythrocytes.

ABSTRACT
The aim of the investigation is studying of erythrocytes charge balance in patients with chronic obstructive pulmonary disease (COPD) of bronchitic and mixed types. The similar trend of change Δ pH of erythrocytes in patients with COPD was observed during the incubation of red blood cells in the range of 37-58 ˚C. The thermograms represented decreasing curve, Δ pH ranged from -0.326 to -0.453 (the average value was -0.383). During subsequent 20- minute incubation of erythrocyte suspension at 58 ˚C, two main types of thermal images, depending on the degree of respiratory failure were recorded. Possible mechanisms of the erythrocytes charge balance alterations in patients with COPD are discussed.

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