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Comparative evaluation of efficiency of proton pomp inhibitors of the first and second generations in treating gastroesophageal reflux disease

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Author(s): Mirvasit KARIMOV | Abdujabar AKHMATKHODJAEV

Journal: European Medical, Health and Pharmaceutical Journal
ISSN 1804-5804

Volume: 2;
Start page: 36;
Date: 2011;
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Keywords: Gastroesophageal Reflux Disease | Rabeprazole | Omeprazole

ABSTRACT
Comparative assessment of clinical efficiency of omeprazole and rabeprazole in treating gastroesophageal reflux disease(GERD). 65 patients with a verified diagnosis GERD were examined. Comparative clinical investigations of using ofomeprazole and rabeprazole have revealed effectiveness of both drugs in the therapy of GERD. However, rabeprazoleshowed antisecretory action in the earlier periods, providing stable clinical remission of GERD and early scarring of erosivelesions of the esophageal mucosa, compared with omeprazole.
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