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COMPARATIVE STUDY FOR ATHEROGENIC INDEX OF PLASMA(AIP) IN PATIENTS WITH TYPE1 DIABETES MELLITUS,TYPE2 DIABETES MELLITUS,BETATHALASSEMIA,AND HYPOTHYROIDISM

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Author(s): Tariq M. Ali Rajab

Journal: International Journal of Chemical Sciences and Research
ISSN 2249-0329

Volume: 02;
Issue: 03;
Start page: 01;
Date: 2012;
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Keywords: Diabetes Mellitus | thalassemia | hypotyrodidism | atherogenic Index of plasma

ABSTRACT
This study will examine the predictive value to atherosclerosis in diabetes mellitus (Type1, and Type2), Beta-thalassemia major (BTM), and hypothyroidism by using the value of AIP, ratio TC/HDL-c and ratio of LDL-c/HDL-c to provide prediction to accelerated development of atherosclerosis in such patients.The present study was performed on patients of both sexes the age ranged between (12-55) years. Sixty seven patients, with different diseases attended different hospitals in Baghdad were included in this study.The patients were grouped as follows: Group I (G1) consist patients of T1 DM (n=15). Their age (12-15 year).Group II (G2) consist patients of BTM (n=18). Their age (12-16 year).Group III (G3) consist patients of T2 DM (n=18). Their age (18-48 year).Group IV (G4) consist patients of Hypothyroidism (n=16). Their age (18-54 year).Two control groups, healthy individuals were also enrolled in this study. (n=30). The first control their age (12-18 year) and the second control their age (20-55 year).A significant increase in plasma Triglyceride of Group 1 and Group 2 compared to control was noticed.A significant increase in plasma Triglyceride and Total cholesterol, also anon significant increases in Low density lipoprotein-cholesterol was found in Group 3 and roup 4 compared to their control.The highest value of AIP was found in group 3 followed by group 1 and group 2. Patients of group 4 were under lower risk than the rest.
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