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Comparison of hematological parameters in untreated and treated subclinical hypothyroidism and primary hypothyroidism patients

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Author(s): Haamid Bashir | Mohmmad Hayat Bhat | Rabia Farooq | Sabhiya Majid | Sheikh Shoib | Rabia Hamid | Arshed Ahmad Mattoo | Tabassum Rashid | Arif Akbar Bhat | Hilal Ahmad Wani | Akbar Masood

Journal: Medical Journal of the Islamic Republic of Iran
ISSN 1016-1430

Volume: 26;
Issue: 4;
Start page: 172;
Date: 2012;
Original page

Keywords: Subclinical hypothyroidism | Primary hypothyroidism | Blood count | Hemoglobin | Red cell distribution | Mean corpuscular volume.

ABSTRACT
 Abstract Backgrounds: Thyroid hormones play an important physiological role in human metabolism. Erythrocyte abnormalities are frequently associated with thyroid disorder. However, they are rarely investigated and related to the subclinical and primary hypothyroidism in Kashmiri Patients. In this study an attempt was made to study hematological parameters in untreated and treated subclinical hypothyroidism and primary hypothyroidism patients. Methods: This retrospective study included 600 subjects, among which were untreated subclinical hypothyroid (n=110), treated subclinical hypothyroid (n=110), untreated primary hypothyroid (n=100), treated primary hypothyroid (n=100) and euthyroid (n=180). This study was carried out at Department of Biochemistry, Government Medical College Srinagar. The hematological parameters and thyroid profile of the subjects were assessed by the Sysmex (Italy) and ECLIA (Germany) 2010 automatic analyzer. Mean, standard deviation (SD), analysis of variance (Two-way ANOVA), and multiple comparisons were used to report our results, with p
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