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Computer simulation of a novel pharmaceutical silicon nanocarrier

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Author(s): Saeed Soltani | Soroush Sardar | Sima Azadi Soror

Journal: Nanotechnology, Science and Applications
ISSN 1177-8903

Volume: 2010;
Issue: default;
Start page: 149;
Date: 2010;
Original page

ABSTRACT
Saeed Soltani, Soroush Sardari, Sima Azadi SororDrug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, IranAbstract: We show the potential of the nanosilicon structure of the frustules of a typical diatom, Cymatopleura sp., as a new vehicle for drugs. The basic diatom nanostructure is a lattice of SiO2, and computerized methods in a dock project have identified the most likely and the best drug types to load into such a structure.Keywords: diatom, docking, artificial neural network, simulation, computerized methods
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