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Condrosarcoma de celulas claras con diferenciacion neuroendocrina: estudio clinico-patologico e inmunohistoquimico de un caso

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Author(s): Eddy VerĂ³nica Mora | Humberto Pontillo | Aldo Reigosa | Eduardo Caleiras | Jorge Mosquera

Journal: Salus Online
ISSN 1316-7138

Volume: 15;
Issue: 2;
Start page: 73;
Date: 2011;
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Keywords: hondrosarcoma | neuroendocrine features

ABSTRACT
We described a case of skeletal clear-cell chondrosarcoma with neuroendocrine differentiation. Case: A male 56-year old patient with a mass in L1, L2, L3 vertebral body, with extension to the soft tissues, and metastasis to both lungs. Histologically, the tumor structure was a lobullated mass, with medium size clear cells and scanty extracelular chondroid matrix. Immunohistochemical studies showed positivity for S-100 protein, neuron specific enolasa and epithelial membrane antigen. Conclusions: Evidence of extraskeletal chondrosarcoma with neuroendocrine features was described. Here, we present a unique case of clear-cell chondrosarcoma with neuroendocrine features
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