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Conservative Therapy of Inflammatory Diseases of Large Intenstine

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Author(s): MATKARIMOV S.R. | RUSTAMOV A.E. | RAHMONOV S.T.

Journal: European Medical, Health and Pharmaceutical Journal
ISSN 1804-5804

Volume: 1;
Start page: 30;
Date: 2011;
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Keywords: CROHN'S DISEASE | NONSPECIFIC ULCEROUS COLITIS | SALOFALK | REMICADE

ABSTRACT
The target of research was the implementation of thecomparative analysis of conservative therapy of preparationof basic therapy and also new methods of treatment(anticytokine therapy). Appointment of salofalk intwos tablets (0, 5) 34 times a day per os, and also 2,0 gr in theform of a rectal enema unitary for a period of seven days,then had transferd the patients to reception 2,0 gr salofalkper os, allowed to achieve substantial improvementpatientsÂ’ cliniclaboratory and endoscopic symptoms witha heavy intensification of ulcer colitis variation, providing fullcliniclabaratory remissions achievements of disease at 8(34 %) patients. In the Minister of the Uzbek Public Healthof the Republican Science Coloproctological Center at 10patients with the IDI have spent the therapy remicade,7 of them had NUC and 3 patients had the Crohn's disease.Therefore, all patients no longer than on the first week afterintroduction of remicade had improvement of a coursedisease which was expressed in defering stool, extinctionor reduction of pathological impurity in excrement andsubsidence bellyaches. During colonoscopical inspection,in 1218 weeks after the first infusion at 80% of the patientshad observed disappearance of ulcers and erosion. In termsof 6 months of supervision of relapse of disease was notnoted. All new directions in treatment of the IDI, apparently,are perspective, but while are proved only theoretically andhad no practical development. Unique and enough effectiveand safe method at the IDI and already has clinicalacknowledgement is remicade.

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