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“CORONARY ARTERY DISEASE ON AUTOPSY”: A FIVE YEARS CLINICOPATHOLOGICAL STUDY (NOVEMBER-2007 TO OCTOBER-2012)

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Author(s): Dr Amit H Agravat | Dr Gauravi Animesh Dhruva | Dr Khyati Ranchhodbhai Babaria | Dr Kalpesh G Rathod

Journal: International Journal of Biomedical and Advance Research
ISSN 2229-3809

Volume: 4;
Issue: 2;
Start page: 105;
Date: 2013;
Original page

Keywords: Autopsy | Coronary aretery Disease | Risk Factor | atherosclerosis

ABSTRACT
BackgroundThis study was done to investigate the cause of death due to coronary artery pathology found on autopsies received between November 2007 to October 2012. The study was conducted at the Histopathology laboratory, Pathology Department, P. D. U. Medical College, Rajkot, Gujarat, India.MethodsIn the present study, total 350 postmortem cases with coronary artery specimen received from Saurashtra region(formed by seven districts of Gujarat,India) from November 2008 to October 2012 were considered. Histopathological sectioning of these specimens was done & slides were prepared & stained by Hematoxylin & Eosin stains, examined microscopically for coronary artery pathology. Each and every autopsy cases received irrespective of natural, unnatural or sudden death were considered for this study. Patients’ relatives were approached and detailed history about the life style, habit & clinical complains of the patient was noted for further evaluation.ResultsA direct relationship was observed between death due to coronary artery disease and personal history including risk factors like sedentary life style, smoking, alcohol, obesity, diabetes & also with particular age groups viz. 45-65 years.ConclusionsOur study confirms that coronary artery diseases are more common among the population with sedentary life style, habit of smoking, alcohol & obesity. Also relationships with diabetes & hypertension were observed. These signify, increasing incidence of coronary artery diseases with modernization & adaptation of western lifestyle in the developing countries as emphasized by this study in our study population. These informations are valuable in policy formation for the control of coronary as artery diseases.
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