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Current treatment of post-menopausal osteoporosis

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Author(s): Helena Canhão

Journal: Acta Obstetrica e Ginecologia Portuguesa
ISSN 1646-5830


ABSTRACT
Post-menopausal osteoporosis is a relatively prevalent disease, associated with an increased risk of bone fractures. Fractures cause disability, increased morbidity and mortality and have therefore a high social and economic impact. In recent years, novel pathways in the pathophysiology of osteoporosis have been unravelled. Central regulatory systems such as the RANK-RANKL-OPG have been described and this has allowed the development of new targeted therapies. Further cell and molecular key pathways could in future became potential targets for therapy. In this review, current treatment options for post-menopausal osteoporosis are described, together with possible new targets for future treatments.
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