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Determinants of coronary collateral circulation in patients with coronary artery disease

Author(s): Cafer Zorkun | Emre Akkaya | Ali Zorlu | İzzet Tandoğan

Journal: Anadolu Kardiyoloji Dergisi
ISSN 1302-8723

Volume: 13;
Issue: 2;
Start page: 146;
Date: 2013;
Original page

Keywords: Coronary collateral circulation | coronary artery disease | high-sensitivity C-reactive protein | regression analysis

Objective: This study aims to identify possible determinants of coronary collaterals in patients with severe coronary artery disease. Methods: The current study has a retrospective cohort design. Seventy four patients with ≥90% stenosis or total occlusion of the left anterior descending artery (LAD) were enrolled; coronary collateral grades, high-sensitive C-reactive protein (hs-CRP), fibrinogen, protein C and S, lipids, uric acid levels and medications applied before coronary angiography were noted and compared. Multiple logistic regression analysis was used for the multivariate analyses of independent variables associated with the development of adequate coronary collateral vessels.Results: The presence of coronary collaterals was significantly higher in males (p=0.018), with higher hs-CRP (p=0.023), prior statin use (p=0.022), and higher Gensini scores (p
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