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Determination of methylxanthines in samples of guarana (Paullinia cupana Kunth) powder sold in pharmacies Feira de Santana, Bahia

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Author(s): Jonaldo André da Costa, Monick Oliveira Ribeiro, Ivonildo Almeida dos Santos, Raquel Bianca Marchesine de Almeida, Amanda dos Santos Teles | Hugo Neves Brandão

Journal: Exatas Online
ISSN 2178-0471

Volume: 2;
Issue: 2;
Start page: 1;
Date: 2011;
Original page

Keywords: methylxantines | Paullinia cupana Kunth | spectrophotometry

ABSTRACT
Guarana (Paullinia cupana Kunth) is a species native to the Amazon region of Brazil, which haspharmacological activity stimulant of central nervous system. This is attributed to the presence ofsecondary metabolites known as methylxanthines (caffeine, theophylline and theobromine) found in theseeds. Due to the large consumption and marketing of food supplements based on guarana seeds, thisstudy aims to determine the levels of methylxanthines in commercial samples of powdered seeds ofPaullinia cupana Kunth. The methylxanthines content was determined by spectrophotometry (λ = 271nm), as recommended in the Brazilian Pharmacopoeia 4th edition and establishes a minimum content of5% of methylxanthines. Two of three samples analysed showed lower levels of methylxanthines thatrecommended by the Pharmacopeia.

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