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Diastolic dysfunction assessment by pulsed-wave and tissue Doppler imaging in diabetic patients with nonalcoholic fatty liver disease

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Author(s): Adela Şerban | Florin Casoinic | Cătălina Bădău

Journal: Human & Veterinary Medicine
ISSN 2066-7655

Volume: 4;
Issue: 2;
Start page: 58;
Date: 2012;
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Keywords: nonalcoholic fatty liver disease | type 2 diabetes mellitus | tissue Doppler imaging | diastolic dysfunction

ABSTRACT
Objective: The purpose of the study was to assess if nonalcoholic fatty liver disease (NAFLD) in diabetic patients increases the riskand/or severity of diastolic dysfunction. Material and methods: 73 diabetic patients with NAFLD and a control group of 70 diabetic patientswithout NAFLD were studied. All patients had normal left ventricular systolic function and blood pressure values under medication. Left ventriculardiastolic dysfunction was assessed by pulsed wave Doppler and tissue Doppler imaging, studying mitral inflow patterns and E wave,E’ wave velocities, E/A and E/E’ ratios. Results and conclusions: The frequency of diastolic dysfunction was significantly higher in diabeticpatients with NAFLD versus controls, with a higher severity.

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