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Dietary Polyphenols and Human Health

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Author(s): V. Mudgal | N. Madaan | A. Mudgal | S. Mishra

Journal: Asian Journal of Biochemistry
ISSN 1815-9923

Volume: 5;
Issue: 3;
Start page: 154;
Date: 2010;
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Keywords: cardiovascular diseases | neurodegenerative disorders | antioxidants | Oxidative stress | cancers | diabetes mellitus | apoptosis

ABSTRACT
in vitro and many of their biological actions have been attributed to their intrinsic reducing capabilities. Research on the effects of dietary polyphenols on human health has developed considerably in the past 10 years. It strongly supports a role for polyphenols in the prevention of degenerative diseases, particularly cardiovascular diseases, osteoporosis, neurodegenerative, diabetes mellitus and cancers. The antioxidant properties of polyphenols have been widely studied, but it has become clear that the mechanisms of action of polyphenols go beyond the modulation of oxidative stress. Polyphenols are currently sold as nutritional supplements. Yet the scientific basis for the health claims for polyphenols is mostly weak. Results from in vitro studies are often directly translated into possible beneficial health effects in humans. However, in the body, polyphenols are quickly and easily converted into polyphenol metabolites. Presented review on Polyphenols and Health, offers an overview of the experimental, clinical and epidemiologic evidence of the effects of polyphenols on health.]]>
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