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Early outcome of aortic valve replacement with mechanical prosthesis in patients with aortic stenosis. Is patient-prosthesis mismatch a significant clinical problem?

Author(s): Sławomir Jander | Mirosław Bitner | Bogdan Jegier | Stanisław Ostrowski | Ryszard Jaszewski

Journal: Archives of Medical Science
ISSN 1734-1922

Volume: 3;
Issue: 1;
Start page: 57;
Date: 2007;
Original page

Keywords: aortic valve replacement | patient-prosthesis mismatch

ntroduction: Prevalence of aortic valve disease increases with a population’s aging. Aortic valve replacement (AVR) is one of the most frequently performed procedures in cardiac surgery centres. Patient-prosthesis mismatch (PPM) is believed by some authors to be a significant clinical problem. The aim of the present study was to assess early results of AVR in patients with isolated aortic valve stenosis, with special regard to haemodynamic parameters and PPM. Material and methods: Forty-eight consecutive patients (28 men and 20 women) aged mean 59.3±12.1 years, who underwent AVR with a mechanical prosthesis, in the Department of Cardiac Surgery, Medical University of Lodz, Poland in 2003, were retrospectively analyzed. Results: The in-hospital postoperative mortality in the study group was 4.2%. The most common postoperative complications were arrhythmia and low cardiac output syndrome (LCOS), which occurred in 5 patients (10.4%) each. At discharge from hospital no patient met the criterion of PPM (effective orifice area index – EOAI of 0.85 cm2/m2 or lower). Significant improvement was observed in mean New York Heart Association (NYHA) class and mean maximal valvular gradient (respectively 2.3±0.5 vs. 1.4±0.7 and 87.1±19.1mmHg vs. 26.4±6.5 mmHg, p
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