Author(s): Bagel J
Journal: Psoriasis : Targets and Therapy
ISSN 2230-326X
Volume: 2011;
Issue: default;
Start page: 1;
Date: 2011;
Original page
ABSTRACT
Jerry BagelPsoriasis Treatment Center of Central New Jersey, East Windsor, NJ, USATwenty-five years ago, inpatient Goekerman therapy was considered to be the "gold standard" treatment for psoriasis. We thought PUVA (psoralen + ultraviolet A light) worked because it intercalated keratinocytes inhibiting cell division, methotrexate affected keratinocytic proliferation, and broadband ultraviolet B creating thymine dimers which also prevented keratinocytic proliferation. The idea that psoriasis was an immunologic disease was in its embryonic development.
Journal: Psoriasis : Targets and Therapy
ISSN 2230-326X
Volume: 2011;
Issue: default;
Start page: 1;
Date: 2011;
Original page
ABSTRACT
Jerry BagelPsoriasis Treatment Center of Central New Jersey, East Windsor, NJ, USATwenty-five years ago, inpatient Goekerman therapy was considered to be the "gold standard" treatment for psoriasis. We thought PUVA (psoralen + ultraviolet A light) worked because it intercalated keratinocytes inhibiting cell division, methotrexate affected keratinocytic proliferation, and broadband ultraviolet B creating thymine dimers which also prevented keratinocytic proliferation. The idea that psoriasis was an immunologic disease was in its embryonic development.
