Author(s): Petrović-Kosanović Dragana | Ajdžanović V. | Čakić-Milošević Maja | Koko Vesna | Milošević Verica
Journal: Archives of Biological Sciences
ISSN 0354-4664
Volume: 65;
Issue: 3;
Start page: 905;
Date: 2013;
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Original page
Keywords: Acute heat stress | rat | adrenal cortex | proliferation | apoptosis
ABSTRACT
Hyperthermia can cause significant structural and functional reorganization of tissues and organs. The proliferative and apoptotic processes of rat adrenal cortex were analyzed by light and electron microscopy after an acute exposure to high ambient temperature. Animals were divided in two groups. The first group consisted of intact controls. The rats from the second group were exposed to a high ambient temperature of 38°C for 60 min. Mitotic chromosomes and the largest number of immunoreactive nuclei for the Ki-67 were observed in the zona reticularis (ZR) of the control animals. The relative number of mitoses after heat stress showed a significant decrease in the zona glomerulosa (ZG; 66.8%), zona fasciculata (ZF; 27.8%) and ZR (86.7%) (for all zones p
Journal: Archives of Biological Sciences
ISSN 0354-4664
Volume: 65;
Issue: 3;
Start page: 905;
Date: 2013;
VIEW PDF
DOWNLOAD PDF Original pageKeywords: Acute heat stress | rat | adrenal cortex | proliferation | apoptosis
ABSTRACT
Hyperthermia can cause significant structural and functional reorganization of tissues and organs. The proliferative and apoptotic processes of rat adrenal cortex were analyzed by light and electron microscopy after an acute exposure to high ambient temperature. Animals were divided in two groups. The first group consisted of intact controls. The rats from the second group were exposed to a high ambient temperature of 38°C for 60 min. Mitotic chromosomes and the largest number of immunoreactive nuclei for the Ki-67 were observed in the zona reticularis (ZR) of the control animals. The relative number of mitoses after heat stress showed a significant decrease in the zona glomerulosa (ZG; 66.8%), zona fasciculata (ZF; 27.8%) and ZR (86.7%) (for all zones p
