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Elevated prealbumin level following high thyroid hormones levels

Author(s): Hiroyuki Kinoshita | Mutsuko Yasuda | Marina Mori | Fumiatsu Yakushiji

Journal: Endocrinology Studies
ISSN 2038-9515

Volume: 3;
Issue: 1;
Start page: e4;
Date: 2013;
Original page

Keywords: thyroid hormones | thyroid hormone-binding proteins | prealbumin | hyperthyroidism

This study is the first to report about a patient with high prealbumin level [56.8 mg/dL (reference range 22.0-40.0 mg/dL)] following elevation in thyroid hormones levels. Among the thyroid hormones, tetraiodothyronine (free T4 and total T4) level showed an elevation. Triiodothyronine (free T3 and total T3) level was within normal limits. Since prealbumin mainly transports T4, the elevation of prealbumin level along with T4 level is reaso- nable. When patients have chronic hyperthyroidism without thyroid-stimulating hormone receptor antibody (TRAb), a diagnosis will be Negative Graves’ disease. However, a part of patients with Negative Graves’ disease may be High prealbumin syndrome.
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