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Enthesopathy and the Cutaneous Disease Activities in Psoriatic Arthritis

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Author(s): Mohieldin M Ahmed | Naglaa M Sayed | Aziz K Alfeeli | Ayyoub B Baqer

Journal: Macedonian Journal of Medical Sciences
ISSN 1857-5749

Volume: 6;
Issue: 2;
Start page: 162;
Date: 2013;
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Keywords: Psoriatic arthritis (PsA) | enthesopathy | Leeds Enthesitis Index (LEI) | CRP and Psoriasis Area and Severity Index (PASI).

ABSTRACT
Aim: To investigate entheseal abnormalities by using Leeds Enthesitis Index (LEI) score in Psoriatic arthritis (PsA). Also, to find the correlation of LEI score and parameters of the activities of the cutaneous disease at baseline and after 6 months of treatment in PsA. Furthermore, to find correlation between LEI score and C-reactive protein (CRP) and Psoriasis Area and Severity Index (PASI) score as well as acute phase reactants.Materials and Methods: A total of thirty-nine patients with PsA and thirty-five age and sex matched healthy subjects were recruited. Clinical and laboratory assessment of disease activity included LEI score, PASI score, erythrocyte sedimentation rate (ESR) and CRP and were measured at baseline and after 6 months of treatment. Results: Enthesopathy showed a significant prevalence among PsA of 20.5%. We found a highly significant decreased in LEI score, PASI score, ESR and CRP at baseline compared to results after 6 months of treatment in PsA. A significant correlation between PASI score and LEI score was found. Also, PASI score was significant correlated with ESR and CRP in PsA.Conclusion: Enthesopathy showed a significant prevalence among PsA. The good potential parameters for PsA were LEI score, PASI score, ESR and CRP in PsA. Also, they may be the predictive value of changes induced by biological treatment in PsA.
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